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Breast Cancer Clinical Trials

A listing of Breast Cancer medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.


Found (1991) clinical trials

A Study to Investigate the Regional Brain Kinetics of Brain Drug Transporters Using P-glycoprotein and Breast Cancer Resistance Protein Substrates and by Using the Positron Emission Tomography Ligand 11C-JNJ-63779586 in the Human Brain

The purpose of this study is to investigate the total body biodistribution and radiation dosimetry of 11C-JNJ-63779586 by Positron Emission Tomography (PET) in healthy young adult males (Part A); to estimate and compare the uptake, distribution, and clearance of 11C-JNJ-63779586 in the brain by PET between mild Alzheimer Disease (AD) ...


What Factors Affect Breast Cancer Neoadjuvant Chemotherapy Efficacy?

In this single group longitudinal study, the investigators propose that functional images from magnetic resonance (MR) methods performed at baseline and after 6 cycles of neoadjuvant chemotherapy (NACT) are in agreement with histological findings from pre-treatment biopsy and post-treatment surgically excised tissue. MR methods will be performed at baseline (pre-treatment) ...

Phase N/A

Omission of Radiation in Patients With Her-2 Positive Breast Cancer

Participants, ages 50 and older diagnosed with stage I or stage II her-2 positive, node negative breast cancer patients will be recommended to continue trastuzumab +/- pertuzumab therapy after surgery to complete a full year of therapy as standard of care under the clinical management of the patient's medical oncologist. ...

Phase N/A

Pharmacokinetics of SPI-2012 (Eflapegrastim) in Breast Cancer Patients Receiving Docetaxel and Cyclophosphamide (TC) Chemotherapy

This is a Phase 1, single-arm multicenter study to evaluate the PK and safety of SPI-2012 (a long acting myeloid growth factor) in breast cancer patients treated with TC chemotherapy. Approximately 25 patients will be enrolled. Each cycle will be 21 days and patients will receive 4 cycles of treatment ...


Metronomic PLD in Patients With Primary Endocrine Resistant ABC

Efficacy and Safety of Metronomic Pegylated Liposomal Doxorubicin in Patients with Primary Endocrine Resistant Advanced Breast Cancer


Hypoglossal Acupuncture for Dysgeusia in Patients Undergoing Chemotherapy

Taste disorders are frequent side effects in patients undergoing chemotherapy (CTX). Dysguesia has prevalence rates of 16% to 1000% during CTX with sometimes also persistent courses. Impact of dysguesia on appetite, body weight as well as health-related quality of life was shown. Until now, evidence for adequate treatment options is ...

Phase N/A

Alternative Exercise Program to Improve Skeletal Muscle Function and Fatigue in Cancer Survivors

Exercise training has beneficial effects in cancer survivors to minimize some of the side effects of cancer and its treatment and improve long-term prognosis, but there are numerous hurdles for individuals diagnosed with, and being treated for, cancer to participate in exercise programs. The goal of this research study is ...


Evaluating a Novel Web-based Intervention for Breast Cancer Survivors

Depression and fatigue is common in breast cancer survivors and its presence is associated with personal suffering, increased inflammatory activity, and worse prognosis. While in the phase of acute treatment many women receive short-term psychological support to better cope with the situation, this is not standard of care in the ...

Phase N/A

Prospective Biobanking Study in Ovarian Breast and Head and Neck Cancer Patients Aiming at Better Understand the Link Between the Molecular Alterations of the Tumor Itself Its Microenvironment and Immune Response (SCANDARE)

Patients will have blood and +/- tumor samples at the following times : if eligible for surgery : at surgery (blood + tumor and nodes) after surgery (blood) before cycle 1 of adjuvant chemotherapy (blood + tumor biopsie and nodes if possible) before cycle 2 of adjuvant chemotherapy (blood) at ...

Phase N/A

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

The purpose of this study is to compare using bupivacaine (a numbing medicine) along with the usual medications for post-operative pain control to using the usual medications for post-operative pain control alone. The addition of bupivacaine to the usual pain medications could better manage pain immediately after surgery. This study ...