Diabetes Prevention Clinical Trials

A listing of Diabetes Prevention medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 43 clinical trials
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Weekly Basal Insulin - Allowing More Flexibility With Treating Type 1 Diabetes. (In the Greater Seattle Area.)

We are currently seeking volunteers who are diagnosed with Type 1 Diabetes and who are treating with multiple daily injections (basal and bolus insulin regimens) for the past 1 year. This is a study of an investigational once weekly basal insulin. Participants will be assigned to one of two groups: …

insulin
sugars
hemoglobin a1c
  • 0 views
  • 11 Jun, 2021
  • 1 location
A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects

The overall objective of the EMERGE trial is to determine whether metformin + usual care, compared to placebo + usual care (introduced at the time of initial diagnosis of GDM), reduces a) the need for insulin use, or hyperglycemia (primary outcome measure); b) excessive maternal weight gain; c) maternal and …

oral glucose tolerance test
insulin
tolerance test
fasting
metformin
  • 280 views
  • 23 Jan, 2021
  • 3 locations
Educational Intervention in the First 18 Months of Life to Prevent/Manage Obesity of Children After Gestational Diabetes

In order to evaluate the effect of an educational intervention on mothers with gestational diabetes and their offspring in the first 18 months of life, The intervention will be applied to mothers with gestational diabetes, and a group of mothers without diabetes, against a control group with the normal post-partum …

diabetes
  • 0 views
  • 25 Jan, 2021
  • 1 location
Study to Evaluate the Efficacy and Safety of ORMD-0801 in Subjects With Type 2 Diabetes Mellitus

In this randomized, double-blind, double-dummy, placebo-controlled study, approximately 675 eligible subjects with type 2 diabetes and inadequate control on at least one and up to 3 oral glucose-lowering agents will undergo an initial 21-day Screening Period, followed by a 26-week Double-Blind Treatment Period and a 26-week Double-Blind Treatment Extension Period.

  • 0 views
  • 29 Jan, 2021
  • 1 location
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to insulin lispro (U100) three times a day in participants with type 2 diabetes that are already on insulin glargine (U100), with or without metformin.

insulin
type 2 diabetes mellitus
hemoglobin a1c
metformin
  • 0 views
  • 13 Jun, 2021
  • 160 locations
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
hemoglobin a1c
  • 593 views
  • 13 Jun, 2021
  • 873 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

c-peptide
insulin
fasting
metformin
body mass index
  • 271 views
  • 14 Jun, 2021
  • 105 locations
Medical Optimization of Management of Type 2 Diabetes Complicating Pregnancy (MOMPOD)

Purpose: The objective of this proposal is to study the safety and efficacy of metformin added to insulin for treatment of type 2 diabetes mellitus (T2DM) among pregnant women. Participants: 950 pregnant women with type 2 diabetes complicating pregnancy from 10 U.S. clinical centers Procedures (methods): Pregnant women with T2DM …

hypoglycemia
prenatal
hypoglycemic agents
type 2 diabetes mellitus
diabetes mellitus
  • 71 views
  • 26 Jan, 2021
  • 10 locations
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

diabetes
glucagon-like peptide-1
hemoglobin a1c
glucagon
  • 0 views
  • 13 Jun, 2021
  • 88 locations
Recent-Onset Type 1 Diabetes Trial Evaluating Efficacy and Safety of Teplizumab

The purpose of this study is to determine whether teplizumab slows the loss of cells and preserves cell function in children and adolescent 8-17 years old who have been diagnosed with T1D in the previous 6 weeks.. Subjects will receive two courses of either teplizumab or placebo treatment 6 months …

diabetes
c-peptide
tolerance test
immune tolerance
  • 320 views
  • 23 Feb, 2021
  • 155 locations