Diabetes Prevention Clinical Trials

We are establishing a registry-based cohort and repository of biological (e.g. blood, urine,saliva, etc.) and environmental (e.g. household dust) specimens (approximately 20,000 participants) in which the donated specimens are linked to the donor s identities, contact information, and some basic demographics through a personal identification number (PIN). Specimens are available ...

The skin is a crucial barrier against external allergens and irritants. Therefore the function of the skin barrier is central regarding evolvement of eczema. In patients with type 1 diabetes (T1D) using insulin pumps and/or glucose sensor, eczema is unfortunately a frequent reaction. The skin consists of three layers: epidermis, ...

Purpose of clinical trial To determine the efficacy, safety and utility of fully automated closed-loop insulin delivery in the home setting in adults with type 2 diabetes requiring maintenance dialysis. Study objectives The study objective is to compare fully automated closed-loop insulin delivery with usual care in adults with type ...

The goal is to help improve counselling and ASA adherence for preeclampsia prevention in pregnant women with SLE. This study could offer the ideal setting for the conduct of a future study assessing the efficacy of ASA for prevention of placenta-mediated complications in SLE pregnancies. For this trial, the investigator ...

The duration of the study per participant will be around 18 weeks :1 or 2 weeks of screening followed by a 4-week run-in period, a 12-week treatment period and a 2 to 4 days follow-up period

In this open-label, parallel-arm randomized controlled trial, adults with T2DM of 7 years duration on 0-2 anti-diabetic medications will be randomized to 8-weeks treatment with either (i) basal insulin glargine, (ii) intensive insulin therapy consisting of glargine and pre-meal insulin lispro, or (iii) glargine and the GLP-1 agonist exenatide (twice ...

Gestational diabetes mellitus (GDM) is a high blood glucose (hyperglycemia) first occurring or first recognized during pregnancy, it is affecting 16.4% of women globally and 36.6 % in this region. It is consistent, strong evidence on the impact of GDM on short and long term health impacts on both mother ...

This local, prospective, non-interventional, company sponsored, multi-center, single-cohort study includes patients treated with Ventavis for PAH. A total of 270 patients (valid for safety analysis) is planned to be enrolled in 5 years. Target population is patients with PAH diagnosis. This study is performed as an all-patient investigation, therefore all ...

There will be two groups of people studied: One group has chosen (independently of this research study) to have weight loss surgery to help them lose weight. Another group will not choose to have any weight loss surgery. All research participants will be tested on thinking and memory processes at ...

Electrical stimulation may offer a unique treatment option to heal complicated and recalcitrant wounds, improve flap and graft survival, and even reduce the likelihood of ulceration. Electrical stimulation has been suggested to reduce infection, improve cellular immunity, increase perfusion, relieve pain, improve plantar sensation, and accelerate wound healing. Electrical stimulation ...