Diabetes Prevention Clinical Trials

A listing of Diabetes Prevention medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 563 clinical trials
Incretin-mimetic Hypoglycemic Drugs and Severe Retinopathy (ANGIOSAFE2)

Experimental data suggest that GLP-1 promote endothelial cell growth and angiogenesis which may have beneficial effects on the cardiovascular system but harmful effects on the retina . This project investigate the possible link between incretin therapy and Severe Diabetic Retinopathy. The prevalence of severe DR in patients exposed to incretin …

glucagon-like peptide-1
retinopathy
antidiabetic agents
hypoglycemic agents
incretins
  • 0 views
  • 23 Feb, 2022
  • 1 location
SGLT2 Inhibitor or Metformin as Standard Treatment of Early Stage Type 2 Diabetes (SMARTEST)

A real-world, nationwide, register-based, randomised trial (RRCT) comparing SGLT2 inhibitors with metformin as standard treatment in early typ 2 diabetes. An open-label trial addressing efficacy with respect to clinically important macro- and microvascular events.

sglt2
dapagliflozin
sglt2 inhibitor
metformin
  • 78 views
  • 09 Feb, 2022
  • 1 location
Precision Medicine in Chinese Patients With Young Onset Diabetes

Patients with young onset diabetes (YOD) are one of the most challenging groups of patients due to their long disease duration, complex causes, delayed interventions, psychosocial stress, poor adherence and frequent default. The investigator's previous studies indicate that provision of biogenetic information improved satisfaction, reduced ambiguity and improved self-efficacy in …

insulin resistance
sulfonylurea
insulin
  • 1 views
  • 24 Feb, 2022
  • 1 location
Chronotherapy With Low-dose Aspirin for Primary Prevention (CARING)

Brief summary: Aspirin (ASA) has been shown to provide marked benefits in primary and secondary prevention of cardiovascular events. Substantial evidence suggests that low-dose ASA therapy should also be used as a primary prevention strategy in men and women with diabetes who are at high cardiovascular risk. On the other …

fasting
hypertension
aspirin
metabolic syndrome
Accepts healthy volunteers
  • 21 views
  • 23 Jan, 2022
  • 19 locations
Aspirin Twice a Day in Patients With Diabetes and Acute Coronary Syndrome (ANDAMAN)

To compare treatment with Aspirin Protect twice a day (100 mg in the morning and 100 mg in the evening) versus Aspirin Protect 100 mg once per day on a composite end-point of ischemic events in diabetic patients, or in patients with a known risk factor for non-optimal aspirin response …

q waves
glycosylated hemoglobin
chest pain
cardiac troponin
electrocardiogram
  • 0 views
  • 25 Jan, 2022
  • 1 location
A Quality Improvement Process to Support Delivery of Cardiovascular Care in Community Mental Health Organizations

This pilot study will examine whether an implementation strategy will improve delivery of evidence-based care for cardiovascular risk factors for people with serious mental illness.

rehabilitation therapy
Accepts healthy volunteers
  • 0 views
  • 23 Mar, 2022
  • 1 location
Vitamin D in Pregnancy

Danish pregnant women are recommended ad daily vitamin D supplement of 10 g. Despite the fact that 9 out of 10 women take vitamin D supplements, more than 40% of pregnant women are vitamin D deficient, putting them at an increased risk of pregnancy complications like fetal growth restriction and …

  • 0 views
  • 06 May, 2021
  • 2 locations
Evaluation of the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects With Type 2 Diabetes on Insulin Therapy (REVITALIZE 1)

The Revita® system is being investigated to assess the efficacy of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled with insulin therapy. The purpose of this study is to demonstrate the efficacy and safety of the Fractyl …

hemoglobin a1c
insulin
fasting
glycosylated hemoglobin
body mass index
  • 17 views
  • 08 Jun, 2022
  • 20 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

hemoglobin a1c
insulin
c-peptide
fasting
type 2 diabetes mellitus
  • 506 views
  • 19 Jun, 2022
  • 73 locations
Randomized Trial Comparing Two Sirolimus-Eluting Stents in Diabetes Mellitus (INC-DM)

Randomized, controlled, blind, single-center and non-inferiority clinical trial to compare the target lesion failure (TLF) at 12 months in patients with diabetes mellitus who underwent percutaneous coronary intervention with an Orsiro stent vs. Abluminus stent.

sirolimus
diabetes
hba1c
hemoglobin a1c
fasting
  • 0 views
  • 19 Jun, 2022
  • 1 location