Diabetes Prevention Clinical Trials

A listing of Diabetes Prevention medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 69 clinical trials
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DANHEART (H-HeFT and Met-HeFT)

The present study is testing in a combined design to types of drugs in patients with chronic heart failure: 1) Hydralazine in combination with isosorbide dinitrate (BiDil) and 2) Metformin hydrochloride. The study is double blind, placebo controlled. The first hypothesis is that hydralazine in combination with isosorbide dinitrate can …

fasting
hemoglobin a1c
systolic blood pressure
beta blockers
chronic heart failure
  • 62 views
  • 06 Oct, 2021
  • 33 locations
None
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at …

oral hypoglycemic
rifampin
riboflavin
glycosylated hemoglobin
hemoglobin a1c
  • 514 views
  • 13 Oct, 2021
  • 30 locations
None
Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CFZ533 on preservation of residual pancreatic -cell function in new onset T1DM in pediatric and young adult subjects.

immune tolerance
insulin treatment
c-peptide
tolerance test
insulin
  • 13 views
  • 03 Oct, 2021
  • 12 locations
None
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

diabetes
glucagon
hemoglobin a1c
glucagon-like peptide-1
  • 36 views
  • 16 Oct, 2021
  • 94 locations
None
A Study to Evaluate the Efficacy and Safety of DBPR108 100 mg in Type 2 Diabetes Mellitus Patients

This study will evaluate the efficacy and safety of 100 mg DRBP108 tablets in the treatment of type 2 diabetes mellitus. A total of 750 subjects will be randomly allocated to three groups: DRBP108, active comparator and placebo comparator, in a 3:1:1 ratio. The purpose of this study is to …

oral hypoglycemic
sitagliptin
hemoglobin a1c
type 2 diabetes mellitus
hypoglycemic agents
  • 0 views
  • 04 Oct, 2021
  • 1 location
None
NC Works4Health: Reducing Chronic Disease Risks in Socioeconomically Disadvantaged Unemployed Populations

The proposed study, NC Works4Health (NCW4H), builds on the strengths of long-standing academic-community research partnerships between this UNC at Chapel Hill (UNC) team of investigators and key stakeholders across health, social service, employment, and economic development sectors. The overall goal of this study is to test the effectiveness of a …

diabetes prevention
chronic disease
  • 0 views
  • 01 Oct, 2021
  • 1 location
None
An add-on Study to the FIGARO-DKD Study Called FIGARO-BM to Learn About the Link Between Biomarkers (Substances in the Blood Used as Indicators of Biological Processes Disease Processes or Responses to Medication) and Finerenone in FIGARO-DKD Participants

Researchers are looking for a better way to treat people who have chronic kidney disease (CKD), a long-term, progressive decrease in the kidneys' ability to work properly. When CKD happens in people with type 2 diabetes mellitus, a condition characterized by high blood sugar levels, CKD is also referred to …

type 2 diabetes mellitus
sugars
  • 0 views
  • 15 Oct, 2021
  • 24 locations
None
A Study of LY3502970 in Participants With Type 2 Diabetes Mellitus

The main purpose of this study is to evaluate the efficacy and safety of LY3502970 in participants with type 2 diabetes (T2D) who failed to achieve adequate glycemic control on diet and exercise alone or on a stable dose of metformin. This study will last about 30 weeks.

type 2 diabetes mellitus
metformin
body mass index
  • 6 views
  • 13 Oct, 2021
  • 37 locations
None
Onco-primary Care Networking to Support TEAM-based Care

The proposed ONE TEAM Study is an 18-month, cluster randomized controlled trial. This study will use a sequential multiple assignment randomized trial (SMART) design with a second randomization for the intervention group using a dynamic treatment regimen approach. The investigators propose to randomize 800 adults with newly-diagnosed selected cancers treated …

primary cancer
treatment regimen
cancer
hypercholesterolemia
hypertension
  • 0 views
  • 04 Oct, 2021
  • 1 location
None
Dementia and Diabetes Prevention Program

This is a multicenter, randomized 2-arm clinical trial of two lifestyle interventions varying in intensity and format, in 400 older African American and non-Hispanic whites at increased risk of cognitive decline and dementia in the East San Francisco Bay Area. The trial will include two lifestyle interventions that differ in …

cognitive assessment
dementia
cognitive decline
cognitive impairment
diabetes prevention
  • 0 views
  • 08 Oct, 2021
  • 1 location