Diabetes Prevention Clinical Trials

A listing of Diabetes Prevention medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 114 clinical trials
A Real-World Study of a Mobile Device-based Serious Health Game on Session Attendance in the National Diabetes Prevention Program

Prevention Program (National DPP) in 2010 as a framework for diabetes prevention by providing evidence-based, affordable, and high-quality lifestyle change programs (LCPs). The National DPP LCP is a yearlong

Accepts healthy volunteers
diabetes prevention
body mass index
  • 39 views
  • 18 Apr, 2022
  • 1 location
Elements Vital to Treat Obesity Study (EVO)

randomized controlled trial. The investigators will be comparing the previously developed and optimized behavioral weight loss intervention (APP) to the Diabetes Prevention Program (DPP), to evaluate program

Accepts healthy volunteers
  • 87 views
  • 18 May, 2022
  • 1 location
A Randomized Placebo Controlled Trial of the Effectiveness of Metformin in Addition to Usual Care in the Reduction of Gestational Diabetes Mellitus Effects (EMERGE)

The overall objective of the EMERGE trial is to determine whether metformin + usual care, compared to placebo + usual care (introduced at the time of initial diagnosis of GDM), reduces a) the need for insulin use, or hyperglycemia (primary outcome measure); b) excessive maternal weight gain; c) maternal and …

diabetes
tolerance test
oral glucose tolerance test
fasting
insulin
  • 294 views
  • 26 May, 2022
  • 1 location
A Study to Evaluate THR-149 Treatment for Diabetic Macular Oedema (KALAHARI)

Part A of the study is conducted to select the THR-149 dose level. Part B of the study is conducted to assess the efficacy and safety of the selected dose level compared to aflibercept, up to Month 3. As from Month 3, in about half of the subjects, the effect …

diabetes
sd-oct
spectral domain optical coherence tomography
aflibercept
optical coherence tomography
  • 20 views
  • 25 Apr, 2022
  • 48 locations
Technology-Supported Treatment of Sleep Apnea in Prediabetes (TECH)

Despite the efficacy of intensive lifestyle interventions in prediabetes, the incidence of diabetes is rising, and thus there is a critical need for additional strategies to prevent diabetes and to reduce its cardiovascular complications in this high-risk population. Sleep apnea is a highly common condition in prediabetes, but it has …

diabetes
  • 0 views
  • 29 Apr, 2022
  • 1 location
Evaluation of the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects With Type 2 Diabetes on Insulin Therapy (REVITALIZE 1)

The Revita® system is being investigated to assess the efficacy of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled with insulin therapy. The purpose of this study is to demonstrate the efficacy and safety of the Fractyl …

fasting
body mass index
metformin
insulin
glycosylated hemoglobin
  • 17 views
  • 26 Apr, 2022
  • 18 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

c-peptide
fasting
body mass index
type 2 diabetes mellitus
insulin
  • 505 views
  • 16 May, 2022
  • 74 locations
Eversense® Non-adjunctive Use Post Approval Study (NA-PAS)

This is a non-blinded, prospective, multi-center, single arm longitudinal cohort study (patient serving as their own control), to evaluate the effectiveness of diabetes with the Eversense CGM System non-adjunctively compared to self-monitoring of blood glucose (SMBG) using a blood glucose (BG) meter in participants with either Type 1 or Type …

self-monitoring of blood glucose
  • 0 views
  • 09 May, 2022
  • 13 locations
Investigation of Rifampin to Reduce Pedal Amputations for Osteomyelitis in Diabetics (VA INTREPID)

The purpose of this research study is to determine if rifampin, an antibiotic (a medicine that treats infections), is effective in treating osteomyelitis (infection of the bone) of the foot in diabetic patients. Despite use of powerful antibiotics prescribed over a long period of time, many diabetic patients remain at …

diabetes
debridement
oral hypoglycemic
insulin
antibiotics
  • 631 views
  • 24 May, 2022
  • 25 locations
Personalized Responses to Dietary Composition Trial 3

The PREDICT 3 study will build on previous research in over 2,000 individuals to further refine machine learning models that predict individual responses to foods, with the aim of advancing precision nutrition science and individualized dietary advice. The study incorporates both standardized and controlled dietary intervention, for the purpose of …

diabetes
Accepts healthy volunteers
nutrition education
body mass index
  • 0 views
  • 24 Apr, 2022
  • 2 locations