Diabetes Prevention Clinical Trials

A listing of Diabetes Prevention medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 57 clinical trials
A Study of Tirzepatide (LY3298176) Compared With Dulaglutide on Major Cardiovascular Events in Participants With Type 2 Diabetes

The purpose of the trial is to assess the efficacy and safety of tirzepatide to dulaglutide in participants with type 2 diabetes and increased cardiovascular risk.

body mass index
cardiovascular disease
hemoglobin a1c
  • 593 views
  • 24 Jun, 2021
  • 881 locations
Ertugliflozin Type 2 Diabetes Mellitus (T2DM) Pediatric Study (MK-8835/PF-04971729) (MK-8835-059)

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

body mass index
type 2 diabetes mellitus
fasting
metformin
hemoglobin a1c
  • 271 views
  • 23 Jun, 2021
  • 106 locations
A Study of Tirzepatide (LY3298176) Versus Insulin Lispro (U100) in Participants With Type 2 Diabetes Inadequately Controlled on Insulin Glargine (U100) With or Without Metformin

The purpose of this study is to compare the safety and efficacy of the study drug tirzepatide to insulin lispro (U100) three times a day in participants with type 2 diabetes that are already on insulin glargine (U100), with or without metformin.

type 2 diabetes mellitus
metformin
hemoglobin a1c
insulin
  • 0 views
  • 23 Jun, 2021
  • 161 locations
Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CFZ533 on preservation of residual pancreatic -cell function in new onset T1DM in pediatric and young adult subjects.

tolerance test
zinc
c-peptide
glutamic acid
diabetes
  • 10 views
  • 23 Jun, 2021
  • 11 locations
A Study of Tirzepatide (LY3298176) in Participants With Type 2 Diabetes Who Have Obesity or Are Overweight

This is a study of tirzepatide in participants with type 2 diabetes who have obesity or are overweight. The main purpose is to learn more about how tirzepatide affects body weight. The study will last 79 weeks (22 visits).

hemoglobin a1c
glucagon
glucagon-like peptide-1
diabetes
  • 0 views
  • 23 Jun, 2021
  • 90 locations
New Heart Imaging Techniques to Evaluate Possible Heart Disease

Background Imaging tests, such as magnetic resonance imaging (MRI), can provide information about heart and blood vessels. The tests let doctors can see the amount of blood vessel narrowing and vessel wall thickness. This information may help diagnose and treat heart disease and other conditions that lead to heart attacks. …

diabetes mellitus
atherosclerosis
diabetes
fats
cardiovascular disease
  • 105 views
  • 22 Jun, 2021
  • 1 location
A Study of Two Doses of Dulaglutide (LY2189265) in Japanese Patients With Type 2 Diabetes

The purpose of this study is to evaluate the efficacy and safety of 2 doses of dulaglutide in Japanese participants with type 2 diabetes. The study duration is approximately 58 weeks.

body mass index
alpha-glucosidase inhibitor
hemoglobin a1c
sulfonylurea
  • 0 views
  • 16 Jun, 2021
  • 40 locations
Visualizing Beta Cells in Patients With a History of Gestational Diabetes

In order to evaluate the difference in beta cell mass in women with and without a history of gestational diabetes mellitus (GDM), investigators aim to compare quantitative PET imaging of the pancreas between these groups. Investigators propose to measure uptake of 68Ga-NODAGA-exendin-4 in the pancreatic beta cells of these women …

type 2 diabetes mellitus
tolerance test
glucose tolerance test
oral glucose tolerance test
exenatide
  • 1 views
  • 24 Jun, 2021
  • 1 location
Interactive Obesity Treatment Approach for Obesity Prevention in Adults With Early Serious Mental Illness: iOTA-SMI

early serious mental illness (eSMI) that uses text messaging to provide between-visit support. Derived from the lifestyle intervention used in the Diabetes Prevention Program, the parent iOTA targets

obesity treatment
diabetes
  • 7 views
  • 15 Jun, 2021
  • 2 locations
Identifying Therapeutic Targets of Accelerated Sarcopenia

The proposed research is designed to identify the mechanisms that can accelerate loss of muscle size, strength and physical function in type 2 diabetes and with hospitalization in older persons. About of older Americans have type 2 diabetes, and about of the hospitalizations in the USA involve persons older than …

diabetes mellitus
body mass index
type 2 diabetes mellitus
sarcopenia
mini-mental state examination
  • 152 views
  • 23 Jun, 2021
  • 1 location