Diabetes Prevention Clinical Trials

A listing of Diabetes Prevention medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 88 clinical trials
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Has Diabetes Affected Your Life?

Be part of a new approach to Diabetes care! AMCR Institute is currently recruiting for clinical trials to evaluate medical devices and investigational medications for pediatric and adult individuals with Type 1, Type 2 Diabetes, and obesity. AMCR Institute's team is committed to providing superior service to our volunteers and …

diabetes
  • 7 views
  • 29 Nov, 2022
  • 1 location
A Phase 2, Randomised, Multicentre Study to Assess the Dose Level of Multiple THR-149 Injections and to Evaluate the Efficacy and Safety of THR-149 Versus Aflibercept for the Treatment of Diabetic Macular Oedema (DME) (KALAHARI)

Part A of the study is conducted to select the THR-149 dose level. Part B of the study is conducted to assess the efficacy and safety of the selected dose level compared to aflibercept, up to Month 3. As from Month 3, in about half of the subjects, the effect …

diabetes
edema
vascular endothelial growth factor
growth factor
type 2 diabetes mellitus
  • 21 views
  • 27 Oct, 2022
  • 63 locations
Technology-Supported Treatment of Sleep Apnea in Prediabetes (TECH)

Despite the efficacy of intensive lifestyle interventions in prediabetes, the incidence of diabetes is rising, and thus there is a critical need for additional strategies to prevent diabetes and to reduce its cardiovascular complications in this high-risk population. Sleep apnea is a highly common condition in prediabetes, but it has …

diabetes
  • 8 views
  • 11 Oct, 2022
  • 1 location
Randomized Trial Investigating Clinical Outcomes of Two Sirolimus-Eluting Stents in Diabetes Mellitus (INC-DM)

Randomized, controlled, blind, single-center and non-inferiority clinical trial to compare the target lesion failure (TLF) at 12 months in patients with diabetes mellitus who underwent percutaneous coronary intervention with an Orsiro stent vs. Abluminus stent.

hba1c
diabetes
sirolimus
ischemia
angiography
  • 0 views
  • 28 Oct, 2022
  • 1 location
Aspirin With a Novel Twice-a-day Administration in Diabetic Patients With Acute Coronary Syndrome to Minimize Recurrence of Acute Ischemic Events or New Urgent Revascularization (ANDAMAN)

To compare treatment with Aspirin Protect® twice a day (100 mg in the morning and 100 mg in the evening) versus Aspirin Protect® 100 mg once per day on a composite end-point of ischemic events in diabetic patients, or in patients with a known risk factor for non-optimal aspirin response …

hba1c
cardiac troponin
fasting
electrocardiogram
aspirin
  • 0 views
  • 28 Oct, 2022
  • 1 location
A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled Clinical Study to Evaluate the Safety and Efficacy of Ertugliflozin (MK-8835/PF-04971729) in Pediatric Participants (Ages 10 to 17 Years, Inclusive) With Type 2 Diabetes Mellitus

This study will evaluate the safety and efficacy of ertugliflozin (MK-8835) in pediatric participants with T2DM on metformin with/without insulin. The primary hypothesis of the study is that the addition of ertugliflozin reduces hemoglobin A1C (HbA1C) more than the addition of placebo after 24 weeks of treatment.

metformin
type 2 diabetes mellitus
insulin
c-peptide
body mass index
  • 506 views
  • 18 Oct, 2022
  • 70 locations
A Prospective, Randomized, Double-Blind, Sham-Controlled, Multi-Center Pivotal Study to Evaluate the Efficacy and Safety of Duodenal Mucosal Resurfacing Using the Revita® System in Subjects With Type 2 Diabetes on Insulin Therapy (REVITALIZE 1)

The Revita® system is being investigated to assess the efficacy of DMR versus Sham on improvement in Glycemic, Hepatic and Cardiovascular endpoints for patients with Type 2 Diabetes who are inadequately controlled with insulin therapy. The purpose of this study is to demonstrate the efficacy and safety of the Fractyl …

glycosylated hemoglobin
insulin
metformin
body mass index
hemoglobin a1c
  • 40 views
  • 28 Oct, 2022
  • 24 locations
Prevalence of Carbohydrate Intolerance in Lean and Overweight/Obese Children

The purpose of this study is to determine the prevalence of impaired glucose (carbohydrate) tolerance in lean children with a family history of diabetes and in overweight/obese children with or without a family history of diabetes mellitus.

oral glucose tolerance test
diabetes
glucose tolerance test
type 2 diabetes mellitus
  • 174 views
  • 07 Oct, 2022
  • 1 location
Study of Safety and Efficacy of CFZ533 in Type 1 Diabetes Pediatric and Young Adult Subjects (CCFZ533X2207)

The study is a Phase 2, multicounty, multicenter, non-confirmatory, investigator- and subject masked, randomized, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics, and efficacy of CFZ533 on preservation of residual pancreatic β-cell function in new onset T1DM in pediatric and young adult subjects.

diabetes
immune tolerance
insulin
c-peptide
tolerance test
  • 225 views
  • 04 Oct, 2022
  • 17 locations
Comparative Effectiveness of Family vs. Individually Focused Diabetes Education and Support

The objective of this study is to compare the effectiveness of a novel program-Family Support for Health Action (FAM-ACT) - to individual patient-focused diabetes self-management education and support (I-DSMES).

diabetes
  • 0 views
  • 07 Oct, 2022
  • 1 location