Perimenopause Clinical Trials

A listing of Perimenopause medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 5 clinical trials
Cognitive Behavioural Therapy for Sexual Concerns During Perimenopause

Given the high rates and associated impairment of sexual concerns during the menopausal transition, and specifically during perimenopause, our team has developed a CBT protocol specifically

peri-menopausal
menstrual period
hormone therapy
anxiety
depression
  • 7 views
  • 04 Oct, 2022
  • 1 location
Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression

Background Some women who had depression in the perimenopause may have mood symptoms again if they stop estrogen therapy. Estrogen acts in the brain and other

estrogen
mood symptoms
structured clinical interview
antidepressant
depressive episode
  • 232 views
  • 04 Oct, 2022
  • 1 location
Identifying Neurophysiological Mechanisms of Susceptibility to Estradiol Fluctuation and Irritability Symptoms in the Menopause Transition: An Experimental Approach

Women in the menopause transition (perimenopause) experience substantial day-to-day variability in estradiol and have a 2-4-fold increase in major depression risk. About 40% of perimenopausal

estrogen
Accepts healthy volunteers
mammogram
estradiol
progesterone
  • 2 views
  • 24 Oct, 2022
  • 1 location
The Evaluation of Women With Perimenopause-Related Mood and Behavioral Disorders

The purpose of this study is to investigate mood and behavior changes in the time period surrounding and including menopause. This is an observational study; volunteers who participate will not receive any new or experimental therapies. Controversy exists regarding the relationship between estrogen and progesterone (gonadal steroid) changes and midlife-onset …

estrogen
depressive symptoms
antidepressants
gonadotropin
Accepts healthy volunteers
  • 368 views
  • 21 Oct, 2022
  • 1 location
The Effectiveness of Zoladex® 10.8 mg Compared to Zoladex® 3.6 mg in the Treatment of Premenopausal and Perimenopausal Hormone Receptor Positive Breast Cancer: a Retrospective Real World Study

This is a multi-center, retrospective, observational, active-control, non-inferiority, real world study using hospital medical record data, with objectives to evaluate E2 suppressive effect of Zoladex® 10.8 mg is non-inferior to Zoladex® 3.6 mg. Eligible breast cancer patients who received Zoladex® from January 1st, 2015 till the end of the completion …

  • 0 views
  • 29 Oct, 2022
  • 8 locations