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Perimenopause Clinical Trials
A listing of Perimenopause medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found (4) clinical trials
A clinical trial seeking patients for a research study for the treatment of Gastrojejunostomy, Gastric stapling, Fracture, Perimenopause, Sleeve Gastrectomy, Menopause, Premenopause, Osteoporosis
While highly effective both RYGB and SG may lead to increased bone resorption, decreased bone mass, and increased risk of some fractures. Very few studies have compared the effects of the RYGB and the SG on changes skeletal health and findings have been inconsistent. Furthermore, few studies have investigated the ...
Perimenopause-Related Mood and Behavioral Disorders
Controversy exists regarding the relevance of changes in gonadal steroids for midlife onset depressions. The purpose of this protocol is to allow for the careful screening of patients and healthy volunteers for participation in research protocols that examine the role of gonadal steroids in depressions occurring during the perimenopause and ...
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression
Despite the introduction of new antidepressants, major depressive disorder (MDD) remains challenging to treat. Antidepressant effectiveness trials conducted suggest depression remission rates of only 15%-35%. Therefore, new antidepressants with mechanisms that move beyond norepinephrine and serotonin targets are greatly needed. Importantly, comorbid symptoms including anxiety, cognitive complaints and somatic symptoms ...
Effects of an ER Beta Agonist (Lilly Compound LY500307) on Estradiol-Withdrawal-Induced Mood Symptoms in Women With Past Perimenopausal Depression
OBJECTIVE During the perimenopause, the incidence of depression increases 1-5 and predicts increased all-cause and cardiovascular mortality. A role of estradiol withdrawal in the onset of mood disorders in some perimenopausal women has been suggested indirectly by estradiol s antidepressant efficacy and safety in perimenopausal depression. Moreover, observational studies report ...
