Heart Failure Clinical Trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 92 clinical trials
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac

ejection fraction
cardiac resynchronization therapy
medical therapy
  • 24 Jul, 2021
  • 353 locations
Digoxin Short Term Treatment Assessment Randomized Trial in AHF

> Digoxin processes many characteristics of a beneficial drug for heart failure, however recent publications has rose concerns about its safety profile and therefore decreasing its use.

  • 29 Jul, 2021
  • 2 locations
Clinical Study to Compare the Efficacy and Safety of Macitentan and Tadalafil Monotherapies With the Corresponding Fixed-dose Combination Therapy in Subjects With Pulmonary Arterial Hypertension (PAH)

Combination therapy in pulmonary arterial hypertension (PAH) has been the subject of active investigation for more than a decade, with the benefit of targeting different pathways known to be involved in the pathogenesis of the disease. Adherence to prescribed therapy has an impact on clinical outcomes. Reducing the pill/tablet count …

  • 17 Jul, 2021
  • 220 locations
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

FDA-approved multiple sclerosis (MS) disease-modifying therapies (DMTs) target the relapsing phase of MS but have minimal impact once the progressive phase has begun. It is unclear if, in the relapsing phase, there is an advantage of early aggressive therapy with respect to preventing long-term disability. The infectious risks and other …

  • 25 Jul, 2021
  • 50 locations
Interval Training in Heart Failure

Heart failure (HF) is currently considered a common pathology, with 15 million adults in Europe and 26 million worldwide. The American Heart Association (AHA) estimates that their number will

systolic heart failure
cardiac rehabilitation
  • 20 Jul, 2021
  • 1 location
Treatment With the Ketone Body 3-hydroxybutyrate in Patients With Acute Heart Failure

Background Acute heart failure is a potentially life-threatening condition, reaching mortality rates of up to 50% in advanced cases. The investigators have shown

loop diuretic
  • 19 Jul, 2021
  • 1 location
A Study of LY3461767 in Participants With Chronic Heart Failure With Reduced Ejection Fraction

it in participants with chronic heart failure with reduced ejection fraction (HFrEF). The study will last up to 3 months and may include 5 visits.

  • 18 Jul, 2021
  • 6 locations
Evaluate the Effect of Injectable Neucardin on the Cardiac Function of Subjects With Chronic Systolic Heart Failure

pg/ml and female patients with NT-proBNP 4000 pg/ml, NYHA II-III chronic systolic heart failure, and to confirm its efficacy and safety.

  • 30 Jul, 2021
  • 2 locations
Carmat TAH Early Feasibility Study

Feasibility study of the Carmat TAH as a treatment for transplant-eligible patients in severe, end-stage heart failure.

  • 29 Jul, 2021
  • 4 locations
CPNS Pilot Study: Evaluation of Safety and Performance of the Cardiac Pulmonary Nerve Stimulation (CPNS) System in Patients With ADHF

The CPNS Pilot Study: An evaluation of the safety and performance of the Cardionomic Cardiac Pulmonary Nerve Stimulation (CPNS) system in patients with acute decompensated heart failure.

  • 22 Jul, 2021
  • 3 locations