Heart Failure Clinical Trials

A listing of Heart Failure medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 546 clinical trials
Featured trial
B3461087 - Tafamidis

heart failure with preserved ejection fraction (HFpEF)].

  • 09 Jun, 2022
  • 5 locations
Impact of Hypertonic Saline Solution on Acute Decompensated Heart Failure (HSS)

Acute decompensated heart failure (HF) is one of the most common cardiologic issues in emergency departments. Loop diuretics have long been recognized as the key for the treatment of

  • 18 Apr, 2022
  • 1 location
Effect of the MobiusHD® in Patients With Heart Failure (HF-FIM)

This is a prospective, multi-center, open-label clinical trial intended to evaluate the safety and effectiveness of the MobiusHD® in patients with heart failure and reduced ejection fraction.

  • 11 Jul, 2022
  • 9 locations
Re-evaluation of Optimal Re-synchronisation Therapy in Patients With Chronic Heart Failure (RESET-CRT)

The objective of the study is to demonstrate that in patients with chronic heart failure who receive optimal medical treatment for this condition and have indication for Cardiac

cardiac resynchronization therapy
ejection fraction
medical therapy
  • 25 Jul, 2022
  • 168 locations
CPNS Pilot Study: Evaluation of Safety and Performance of the Cardiac Pulmonary Nerve Stimulation (CPNS) System in Patients With ADHF

The CPNS Pilot Study: An evaluation of the safety and performance of the Cardionomic Cardiac Pulmonary Nerve Stimulation (CPNS) system in patients with acute decompensated heart failure.

  • 10 May, 2022
  • 14 locations
Digoxin Short Term Treatment Assessment Randomized Trial in AHF (DIG-STA-AHF)

> Digoxin processes many characteristics of a beneficial drug for heart failure, however recent publications has rose concerns about its safety profile and therefore decreasing its use.

  • 08 Jul, 2022
  • 2 locations
Study to Evaluate the Efficacy and Safety of AZD4831 in Participants With Heart Failure With Left Ventricular Ejection Fraction > 40% (ENDEAVOR)

participants with heart failure with left ventricular ejection fraction > 40%. The study will consist of 2 separate parts, Part A and Part B, approximately 660 participants will be randomised in Part A, 825

  • 24 Jul, 2022
  • 105 locations
A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035) (VICTOR)

The purpose of this study is to evaluate the efficacy and safety of vericiguat in participants with chronic heart failure with reduced ejection fraction (HFrEF), specifically those with

  • 29 Jul, 2022
  • 319 locations
A Study to Assess the Hemodynamic Effects, Safety, Tolerability, and Pharmacokinetics of Intravenous APD418 in Adult Participants With Heart Failure With Reduced Ejection Fraction

The purpose of this study is to evaluate the safety, pharmacokinetics, and effect on cardiac function of intravenous APD418 in adult participants with heart failure with reduced ejection

  • 23 Jul, 2022
  • 17 locations
Balloon vs. Self Expanding Transcatheter Valve for Degenerated Bioprosthesis (BASELINE)

prosthesis patient mismatch is defined by effective orifice area (EOAi) ≤0.65 cm2/m2 2. Safety endpoint at 1 year defined by the composite of all-cause death, disabling stroke, rehospitalization for heart

aortic valve replacement
transcatheter aortic valve implantation
  • 11 Aug, 2022
  • 1 location