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Ichthyosis Clinical Trials

A listing of Ichthyosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (18) clinical trials

If so, you may qualify for a clinical trial at ClinSearch examining the safety and effectiveness of an investigational medication for individuals with Sjogren’s syndrome. Qualified participants may receive: • Study-related medication at no cost • Study-related medical exams at no cost • Reimbursement for travel costs

Phase N/A

A Safety and Tolerability Study of Topical PAT-001 in Congenital Ichthyosis

The management of CI is a life-long endeavor, which remains largely symptomatic (i.e., emollients with or without keratolytics agents) and commonly focused on reducing scaling and/or skin lubrication with both systemic and topical treatments. A first-line therapy includes hydration and lubrication accomplished by creams and ointments containing low concentrations of ...

Phase

Examination of Clinical and Laboratory Abnormalities in Patients With Defective DNA Repair: Xeroderma Pigmentosum Cockayne Syndrome or Trichothiodystrophy

Four rare genetic diseases, xeroderma pigmentosum (XP), Cockayne syndrome (CS), the XP/CS complex and trichothiodystrophy (TTD) have defective DNA excision repair although only XP has increased cancer susceptibility. We plan to perform careful clinical examination of selected patients with XP, XP/CS, CS, or TTD and follow their clinical course. We ...

Phase N/A

Confocal Laser Endomicroscopy in IBS Patients

This study will assess dynamic effects of two major antigens on the duodenal mucosa by confocal laser endomicroscopy (CLE). Patients will be blinded to the antigens used (wheat, yeast). Following CLE it is planned to have a cross over exclusion diet with/without the antigens including a washout phase. Furthermore, patients ...

Phase N/A

Fecal Bile Acids Fecal Short Chain Fatty Acids and the Intestinal Microbioita in Patients With IBS and Control Volunteers

There is emerging evidence that alterations in bile acids and SCFA associated with IBS could be associated with changes in the gut microbiota. In addition to modulating levels of intraluminal organic acids, it has been hypothesized that gut microbiota may alter local immune responses, modulate visceral pain responses, and impair ...

Phase N/A

Integrative Approaches to Managing Irritable Bowel Syndrome (IBS)

This project will test the effectiveness of an integrative medicine approach in treating irritable bowel syndrome (IBS). Over the course of 18 months, we will recruit 85 participants with IBS in New York City. These participants will be randomized to either a 4-week group-oriented treatment intervention incorporating a low FODMAP ...

Phase N/A

Asthma and Atopic Dermatitis Validation of PROMIS Pediatric Instruments

This study involves a series of research and development projects targeted at two of the most common chronic diseases affecting children: asthma and atopic dermatitis (AD, or eczema). The Investigators propose to directly validate patient-reported outcomes (PRO) measures in a large cohort of itch-specific pediatric skin conditions, with a primary ...

Phase N/A

Measuring Nerve Activity in Small Human Intestinal Biopsies in IBS (Irritable Bowel Syndrome)

Rectal biopsies from IBS patients or healthy subjects will be taken. Biopsies will be used for: the isolation of submucosal plexus to perform: 1.1 live nerve recordings and Calcium imaging; 1.2 immunohistochemistry; 1.3 mRNA (Messenger ribonucleic acids) isolation and real time PCR (Polymerase chain reaction); culturing biopsies On the basis ...

Phase N/A

Visceral Sensitivity in IBD (Irritable Bowel Disease) and IBS (Irritable Bowel Syndrome)

Methods Sample collection in healthy subjects, IBD and IBS patients: biopsy of rectum and colon descendens blood sample collection collection of sample of nasal mucosa feces collection questionnaires rectal barostat sensitivity measurement transit measurement of colon MR scan of brain

Phase N/A

Studies of Skin Microbes in Healthy People and in People With Skin Conditions

Skin microbiota (bacteria, fungi, viruses, phage, archae) play a significant role in common dermatological conditions, such as atopic dermatitis/AD (eczema). Since culture-dependent methods are often biased assessments of microbial diversity, genomic methods can expand our understanding of the human microbiome and skin diseases. Chronic dermatitis is typical among rare primary ...

Phase N/A