Urinary Tract Infections Clinical Trials

Urinary tract infections (UTIs) are common and usually treated with antibiotics. We’re studying an investigational drug to see if it may be effective for UTIs in women. Study participants will receive either the investigational drug or a currently approved treatment.

This is a double-blind, randomized, double-dummy, comparative study in parallel groups of subjects presenting with recurrent cystitis (2 episodes within the past 6 months). After initial evaluations including urine culture and antibiogram, a total of 284 subjects will be randomized and treated with one of two presentations of urinary antiseptics ...

According to preassigned 1:1 randomization of 40 patients assigend to intervention group and other 40 patients assign to control group as follow. Get documented agreement from the caregiver if the patient meets the criteria. While the a nurse attaches a kismo to a patient, the researcher at the bedside measures ...

Urinary catheterization is standard practice during and shortly after lung resections. The standard practice is being questioned in an era where unnecessary interventions are being re-considered, particularly since urinary catheterization is not without a risk of adverse events. The study is being done to establish an evidence base to support ...

In 2014, Hilt, Evann et al published a study called "Urine is not sterile," in which it was found via PCR and extended urine cultures, there is a microbiome that exists within the urinary bladder. In this study, 92% of the bacteria failed to be identified by a standard urine ...

The purpose of this study is to characterize the PK ( Pharmacokinetics) of understudied drugs administered to children per standard of care as prescribed by their treating caregiver. This will be accomplished by the collection of biological samples during the time of drug administration per standard of care as prescribed ...

Background 1.1. Urinary tract infection Urinary tract infections (UTI) are considered to be the most common bacterial infections, with approximately 80% of all UTIs occurring in women (1). Nearly one in three women is expected to have at least one episode of UTI by the age of 24 years and ...

The SCOUT Study is a multi-center, centrally randomized, double-blind, placebo-controlled non-inferiority clinical trial of 746 children ages two months (at least 36 weeks gestation from birth for subjects < two years of age) to 10 years with a confirmed diagnosis of a urinary tract infection (UTI) to evaluate 672 for ...

Recurrent urinary tract infections are quickly becoming a public health obstacle in our aging population. Almost 50% of women have at least one urinary tract infection in their lifetime; following this first infection, there is a 25-35% chance that she will have another infection in the subsequent 3-6 months. With ...

In previously published European and global guidelines, there has been no consensus among experts regarding the duration of therapy for a febrile UTI. Depending on the recommendation, the duration of treatment should be between 7-14 days. 221 patients aged 3 months to 7 years with febrile UTIs (defined as a ...