Post Menopause Clinical Trials

A listing of Post Menopause medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 41 clinical trials
Stellate Ganglion Blockade in Post-Menopausal Women (R01)

Hot flashes and night sweats (vasomotor symptoms, VMS) affect 80% of women during the menopausal transition (MT). VMS are associated with decreased quality of life, increased depressive and anxiety symptoms, memory complaints, sleep disturbance, and reduced work productivity. Hormone therapy (HT) is highly effective in reducing VMS, but the use …

serum fsh
flashes
hormone therapy
paroxetine
ganglion
  • 160 views
  • 01 Mar, 2022
  • 2 locations
Effects of Resistance Exercise on Blood Glucose in Post-menopausal Women With Type 1 Diabetes

Regular physical activity has substantial health benefits in people with type 1 diabetes. The fear of hypoglycemia, both during and after exercise, is a major barrier to exercise in this population. A major obstacle to providing specific physical activity and exercise advice is that there are still significant gaps in …

diabetes
hypoglycemia
hemoglobin a1c
  • 0 views
  • 27 Apr, 2022
  • 1 location
A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer

Around 75% of breast cancers are defined and driven by Oestrogen receptor alpha (ER) transcriptional activity. Standard treatment is endocrine therapy however clinical outcomes vary considerably, and a proportion of women with early breast cancer driven by ER transcriptional activity develop drug resistance, and relapse with incurable, metastatic disease. Historically, …

advanced breast cancer
letrozole
estrogen
progesterone
carcinoma
  • 3 views
  • 28 Jan, 2021
  • 1 location
Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women

The investigators propose to genotype males and females at age 40 years and older, who are asymptomatic and without known heart disease (N=2000). DNA from a blood sample will be genotyped for millions of genetic risk variants for CAD by Baylor College of Medicine Human Genome Sequencing Center Clinical Laboratory …

Accepts healthy volunteers
cardiovascular disease
heart disease
  • 0 views
  • 03 Jan, 2022
  • 1 location
HE4 in the Diagnostic Approach of Endometrial Cancer in Patients With Postmenopausal Bleeding

This study aims to explore the sensitivity of an innovative marker, HE4, in the diagnosis approach of endometrial cancer in case of postmenopausal bleedings.

ca-125
cancer
hysterectomy
  • 0 views
  • 27 Sep, 2021
  • 2 locations
The Cardiovascular Impact of Hot Flushes

The overall objective of this study is to examine the physiological responses that occur during a hot flush in postmenopausal women. The following specific aims will be executed to reach the overall objective of this study. Aim 1: To determine if hot flushes can be reliably induced with a temperature-controlled, …

flushes
Accepts healthy volunteers
hormone therapy
  • 6 views
  • 23 Apr, 2022
  • 1 location
Identification of miRNAs Associated With Gender Difference in Osteoarthritis Patients (MIRGOA)

The biological study involves the collection of samples from male and female patients (intraoperative waste tissue, blood and synovial fluid), suffering from mild and moderate-severe OA, who undergo endo or arthro-prosthesis surgery, or arthroplasty, for the identification and characterization of a panel of "gender-specific" miRNAs. MicroRNAs will be extracted from …

joint reconstruction
  • 0 views
  • 06 Apr, 2022
Cushing's Osteoporosis Specificities (SOCS)

Osteoporosis induced by glucocorticoids excess constitutes the main cause of secondary osteoporosis. Most of data available are provided from cohort studies of patients treated by corticosteroids, affecting among 1% of population. In contrast, very few data on osteoporosis are available in the Cushing syndrome (CS), a rare disease affecting 1 …

Accepts healthy volunteers
  • 4 views
  • 25 Feb, 2022
  • 1 location
Psychological Determinants of the Therapeutic Observance of Osteoporotic Patients (OSTEOPSY)

Osteoporosis is a skeletal pathology characterized by decreased bone mass and deterioration of bone tissue. This pathology affects predominantly women, which is estimated that 40% of them will suffer an osteoporotic fracture. The incidence of osteoporosis, thus representing a major public health problem where osteoporotic fractures have a higher incidence …

bone destruction
bone mineral density
bisphosphonate
osteoporotic fracture
prolia
  • 12 views
  • 13 Feb, 2022
  • 1 location
Alendronate in an Weekly Effervescent Tablet Formulation Following Denosumab Discontinuation (BAD)

Discontinuation of denosumab results in a rebound response of bone turnover markers, which rise above baseline at 3 months and remain elevated until reaching again baseline levels approximately 30 months after the last dose. Bone mineral density (BMD) gains are also lost and BMD values reach original baseline values after …

bone mineral density
bisphosphonate
bisphosphonate therapy
risedronate
alendronate
  • 28 views
  • 17 Mar, 2022
  • 1 location