Post Menopause Clinical Trials

A listing of Post Menopause medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 41 clinical trials
Romosozumab Use to Build Skeletal Integrity

The purpose of this study is to find out if one year of romosozumab (Evenity), a monthly injection given in the arm under the skin, prior to an infusion of zoledronic acid Reclast, works to treat bone loss and prevent it from worsening in older women (ages 65 and older) …

osteoporotic fracture
calcium
fragility fracture
zoledronic acid
vitamin d
  • 0 views
  • 15 Oct, 2021
  • 1 location
Stellate Ganglion Blockade in Post-Menopausal Women

Hot flashes and night sweats (vasomotor symptoms, VMS) affect 80% of women during the menopausal transition (MT). VMS are associated with decreased quality of life, increased depressive and anxiety symptoms, memory complaints, sleep disturbance, and reduced work productivity. Hormone therapy (HT) is highly effective in reducing VMS, but the use …

oophorectomy
bupivacaine
night sweats
ganglion
paroxetine
  • 120 views
  • 12 Dec, 2021
  • 4 locations
Exercise Training and Thrombotic Risk in Post-menopausal Women

At menopausal transition, the risk of cardiovascular diseases increases. This is partly due to aging, but largely also the loss of estrogen, which has many positive effects on the circulation and protects against cardiovascular diseases. It has been suggested that the loss of estrogen may have a negative impact on …

clot
estrogen
Accepts healthy volunteers
blood clot
  • 0 views
  • 02 Nov, 2021
  • 1 location
A Pre-operative Window Study of Letrozole Plus PR Agonist (Megestrol Acetate) Versus Letrozole Alone in Post-menopausal Patients With ER-positive Breast Cancer

Around 75% of breast cancers are defined and driven by Oestrogen receptor alpha (ER) transcriptional activity. Standard treatment is endocrine therapy however clinical outcomes vary considerably, and a proportion of women with early breast cancer driven by ER transcriptional activity develop drug resistance, and relapse with incurable, metastatic disease. Historically, …

erbb2
hormone therapy
metastasis
progesterone receptor
endocrine therapy
  • 3 views
  • 28 Jan, 2021
  • 1 location
Exemestane in Post-Menopausal Women With NSCLC

This is a phase II therapeutic study of adding exemestane therapy in post-menopausal women with advanced non-small cell lung cancer (NSCLC) who are progressing while on treatment with an immune checkpoint antibody (pembrolizumab, atezolizumab, or nivolumab).

proto-oncogene tyrosine-protein kinase ros
ROS1
lung carcinoma
metastasis
cancer chemotherapy
  • 34 views
  • 18 Oct, 2021
  • 17 locations
Genetic Risk Stratification for Primary Prevention of CAD in Men and Pre & Post-menopausal Women

The investigators propose to genotype males and females at age 40 years and older, who are asymptomatic and without known heart disease (N=2000). DNA from a blood sample will be genotyped for millions of genetic risk variants for CAD by Baylor College of Medicine Human Genome Sequencing Center Clinical Laboratory …

Accepts healthy volunteers
cardiovascular disease
heart disease
  • 0 views
  • 03 Jan, 2022
  • 3 locations
HE4 in the Diagnostic Approach of Endometrial Cancer in Patients With Postmenopausal Bleeding

This study aims to explore the sensitivity of an innovative marker, HE4, in the diagnosis approach of endometrial cancer in case of postmenopausal bleedings.

cancer
ca-125
hysterectomy
  • 0 views
  • 27 Sep, 2021
  • 2 locations
Effect of Alendronate 70mg Formulation on Bone Turnover Markers and Patient Reported Outcomes

Compare the data obtained with two formulations of alendronate 70 mg (tablets vs effervescent tablet for buffered solution) on the change in bone turnover markers, on gastric tolerance and on treatment adherence (including compliance and persistence).

vitamin d
surgical menopause
calcium
fosamax
alendronate
  • 1 views
  • 26 Jan, 2021
  • 2 locations
Psychological Determinants of the Therapeutic Observance of Osteoporotic Patients

Osteoporosis is a skeletal pathology characterized by decreased bone mass and deterioration of bone tissue. This pathology affects predominantly women, which is estimated that 40% of them will suffer an osteoporotic fracture. The incidence of osteoporosis, thus representing a major public health problem where osteoporotic fractures have a higher incidence …

bone destruction
osteoporotic fracture
bone mineral density
osteoporosis
calcium
  • 12 views
  • 05 Dec, 2021
  • 1 location
Cushing's Osteoporosis Specificities

Osteoporosis induced by glucocorticoids excess constitutes the main cause of secondary osteoporosis. Most of data available are provided from cohort studies of patients treated by corticosteroids, affecting among 1% of population. In contrast, very few data on osteoporosis are available in the Cushing syndrome (CS), a rare disease affecting 1 …

  • 4 views
  • 21 Jan, 2021