Post Menopause Clinical Trials

A listing of Post Menopause medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 41 clinical trials
Insulin Sensitivity After Breast Cancer

Epidemiological studies have revealed that 60-80% of women with breast cancer (BC) develop metabolic disorders that are similar to those observed in conditions like type 2 diabetes. These metabolic disorders, including insulin resistance, obesity, hyperinsulinemia, and glucose intolerance, are associated with increased BC recurrence and mortality. Skeletal muscle is the …

adjuvant chemotherapy
  • 0 views
  • 25 Aug, 2021
  • 1 location
A Neurosteroid Intervention for Menopausal and Perimenopausal Depression

HYPOTHESIS Pregnenolone administration will be associated with greater reduction in depressive symptom severity than placebo in women with current mMDD. STUDY AIMS: Primary Aim: Determine if pregnenolone is associated with greater reduction in depressive symptom severity than placebo in women with mMDD, as measured by MADRS. Secondary Aims: Determine if …

mirena
anxiety
depressive symptoms
major depressive disorder
hot flashes
  • 454 views
  • 02 Sep, 2021
  • 1 location
Coral Calcium's Effect on Bone Density in Postmenopausal Women With and Without Ibandronate

This study will investigate the effect of coral calcium complex supplementation on BMD of osteoporotic individuals either when used alone or in combination with ibandronate. Ibandronate alone will also be tested in comparison to coral calcium supplementation alone or in combination.

calcium
bisphosphonate
vitamins
calcium supplementation
bone mineral density
  • 57 views
  • 24 Jan, 2021
  • 1 location
Comparative Antiresorptive Efficacy Discontinuation of Denosumab

Osteoporosis remains a significant healthcare burden for the United States. Current FDA-approved osteoporosis treatments include teriparatide, abaloparatide, bisphosphonates, denosumab, and raloxifene. Denosumab is a fully human monoclonal antibody that specifically binds to receptor activator of nuclear factor kappa-B ligand (RANKL). Denosumab potently suppresses osteoclastic activity but bone turnover rapidly normalizes …

postmenopausal osteoporosis
raloxifene
RANKL
osteoporosis
denosumab
  • 34 views
  • 02 May, 2021
Bone Modeling Effects of Combined Anabolic/Antiresorptive Administration

The purpose of this study is to examine, via iliac crest bone biopsies, the mechanism of combined teriparatide and denosumab on the bone of postmenopausal osteoporotic women after 3 months of treatment.

crest
denosumab
teriparatide
  • 7 views
  • 11 Apr, 2021
Abaloparatide Added to Ongoing Denosumab vs Continued Denosumab Alone

This randomized open label clinical trial will evaluate the effect of continued denosumab alone over 18 months versus denosumab with added abaloparatide for 18 months. 70 postmenopausal women will be enrolled over a period of 18 months. The co-primary outcomes will be group differences in bone mineral density (BMD) of …

  • 0 views
  • 23 Feb, 2021
  • 1 location
DHEA Augmentation of Musculoskeletal Adaptations to Exercise in Older Women

To determine whether the musculoskeletal adaptations to bone-loading exercise can be significantly augmented in older women (aged 60-85) with low bone mass (osteopenia; T-scores <-1.0 and >-2.5) or moderate osteoporosis (T-scores < -2.5 and >= -3.0) and by restoring serum DHEAS to young adult levels by oral DHEA replacement.

osteoporosis
bone mineral density
osteopenia
  • 15 views
  • 15 Apr, 2021
  • 1 location
Clinical Efficacy and Safety Comparative Study Between CMAB807 Injection and Prolia .

evaluate the differences in effectiveness and safety between CMAB807( potential biosimilar) and Prolia(original product)

hip fracture
x-rays
osteoporotic fracture
body mass index
RANKL
  • 0 views
  • 11 Aug, 2021
  • 1 location
Comparing of the Pharmacokinetic Safety and Immunogenicity of HS-20090-2 Injection and Prolia in Healthy Adults

A randomized, single-blind and parallel group study to compare the pharmacokinetic, safety and immunogenicity of HS-20090-2 60mg#1ml#and Prolia in healthy adults.

prolia
x-rays
  • 0 views
  • 04 Sep, 2021
  • 1 location
Blackcurrant Modifies Gut Microbiota and Reduces Osteoporosis Risk

Aim to evaluate the effects of blackcurrant supplementation on changes in gut microbiome and bone mass in adult women.

vitamin d
bone scans
bone scan
calcium
vitamin d deficiency
  • 0 views
  • 20 Aug, 2021
  • 1 location