Congenital Adrenal Hyperplasia Clinical Trials

A listing of Congenital Adrenal Hyperplasia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 10 clinical trials
Global Safety and Efficacy Registration Study of Crinecerfont in Pediatric Patients With Classic Congenital Adrenal Hyperplasia (CAHtalyst Pediatric Study)

adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency. The study consists of a 28-week double blind, placebo-controlled period, followed by 24 weeks of treatment with crinecerfont. Duration of

classic congenital adrenal hyperplasia
21-ohd
deficiency
  • 3 views
  • 07 Oct, 2022
  • 39 locations
A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Crinecerfont (NBI-74788) in Adult Subjects With Classic Congenital Adrenal Hyperplasia, Followed by Open-Label Treatment (CAHtalyst)

This is a Phase 3 study to evaluate the efficacy, safety, and tolerability of crinecerfont versus placebo administered for 24 weeks in approximately 165 adult subjects with classic CAH due to 21-hydroxylase deficiency. The study consists of a 6 month randomized, double blind, placebo-controlled period, followed by 1 year of …

21-ohd
deficiency
  • 123 views
  • 18 Oct, 2022
  • 60 locations
A Ph2b to Evaluate Clinical Efficacy and Safety of Tildacerfont in Adult CAH

An investigation of the efficacy and safety of up to 70 weeks of treatment with Tildacerfont in subjects with classic CAH who have elevated biomarkers at baseline on their current GC regimen. Optional open label treatment extension period up to 240 weeks with 200mg tildacerfont QD.

prednisone
17-hydroxyprogesterone
21-ohd
prednisolone
deficiency
  • 28 views
  • 07 Oct, 2022
  • 57 locations
A Ph2b to Evaluate Tildacerfont in the Reduction of Glucocorticoid Steroid Doses in Adult CAH

An investigation of the ability of Tildacerfont to reduce supraphysiologic glucocorticoid dosing in classic CAH subjects up to 76 weeks of treatment. Optional open label extension up to 240 weeks.

prednisolone
21-ohd
deficiency
prednisone
  • 10 views
  • 07 Oct, 2022
  • 55 locations
A Study of Gene Therapy for Classic Congenital Adrenal Hyperplasia (CAH)

This study is designed to evaluate the safety, tolerability, and efficacy of AAV5 based BBP-631 in adult participants diagnosed with classic congenital adrenal hyperplasia.

oral hydrocortisone
classic congenital adrenal hyperplasia
21-ohd
  • 6 views
  • 07 Oct, 2022
  • 3 locations
Comparison of Chronocort Versus Standard Hydrocortisone Replacement Therapy in Participants Aged 16 Years and Over With Congenital Adrenal Hyperplasia (CONnECT)

over with Congenital Adrenal Hyperplasia.

fludrocortisone
prednisone
deficiency
prednisolone
replacement therapy
  • 0 views
  • 04 Oct, 2022
  • 6 locations
A Phase 2 Study to Evaluate the Safety, PK, and Exploratory PD of Tildacerfont in Children With CAH

An investigation of the safety of Tildacerfont in pediatric subjects with CAH.

21-ohd
  • 0 views
  • 04 Oct, 2022
  • 4 locations
Application of 68Ga-Pentixafor PET/CT in Primary Aldosteronism and Pre-postoperative of SAAE

Primary aldosteronism is the most common cause of secondary hypertension. The two main types of primary aldosteronism are aldosteronoma(30%) and adrenal hyperplasia(60%). The gold standard that

  • 0 views
  • 04 Oct, 2022
  • 1 location
Natural History Study of Patients With Excess Androgen

other hormones, such as insulin. Two genetic diseases that result in early childhood androgen excess are congenital adrenal hyperplasia (CAH) and familial male-limited precocious puberty (FMPP).

blood tests
deficiency
fasting
blood sugar
insulin
  • 22 views
  • 07 Apr, 2023
  • 1 location
Brain Imaging of Childhood Onset Psychiatric Disorders, Endocrine Disorders and Healthy Volunteers

disorders. The disorders include attention deficit disorder, autism, congenital adrenal hyperplasia, childhood-onset schizophrenia, dyslexia, obsessive compulsive disorder, Sydenham's chorea, and Tourette's

attention deficit disorder
obsessive-compulsive disorder
tourette syndrome
psychiatric disorder
functional magnetic resonance imaging
  • 599 views
  • 11 Apr, 2023
  • 1 location