Idiopathic Inflammatory Myopathies Clinical Trials

A listing of Idiopathic Inflammatory Myopathies medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 60 clinical trials
Clinical Responsiveness of Dermatomyositis Using Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI)

The Evaluation of Clinical Responsiveness Using the Cutaneous Dermatomyositis Disease Area and Severity Index (CDASI), established in 2008, is a one-site database study conducted at the University of Pennsylvania. The database has yielded valuable information and clinical insights into the pathophysiology, disease processes, including psychological responses, treatments and quality of …

dermatomyositis
  • 1 views
  • 24 Jan, 2021
  • 1 location
Musculoskeletal Nociceptive Pain in Participants With Neuromuscular Disorders

, including patients with the following neuromuscular disorders: histologically confirmed inclusion body myositis (IBM), genetically confirmed late-onset Pompe disease (LOPD), genetically confirmed spinal

dyspnea
exercise tests
  • 0 views
  • 18 Jun, 2021
  • 1 location
Prospective Registry of Corona Virus Disease 2019 (Covid-19) Patients With Neuromuscular Involvement

Prospective registry for multimodal assessment of neuromuscular pathology associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, enrolling consecutive patients with corona virus disease 2019 (Covid-19), who are admitted to the intensive care unit of the department of anesthesiology and intensive care medicine, or the department of neurology at …

SARS
creatine kinase
covid-19
infection laboratory
coronavirus infection
  • 0 views
  • 24 Jan, 2021
  • 1 location
Muscle Weakness in COVID-19 Patients

), but also to the direct action of virus (SARS-Cov-2 myositis). The general purpose of the research is to quantify the spread of symptoms and signs of muscle weakness and pain among the patient

  • 0 views
  • 19 Jul, 2021
  • 1 location
ILD-SARDs Registry and Biorepository

A complex interaction between demographic, environmental and genetic mechanisms impact the onset, severity and outcome of ILD-SARDs through dysregulation of the immune system and lung pro-biotic pathways. Comorbidity and genetic risk indicate that there are overlapping pathogenic mechanisms among SARDs, some of which underlie ILD in different SARDs. The purpose …

lung disease
chest ct
connective tissue disease
bronchoalveolar lavage
  • 0 views
  • 18 Sep, 2021
An Exploratory Study on the Efficacy and Safety of Abatacept in the Treatment of Refractory Dermatomyositis

Dermatomyositis is a heterogeneous disease characterized by involvement of the proximal muscles of the extremities. Some patients have treatment failure or intolerance to the above treatment regimens, which is called refractory dermatomyositis. Abatacept has been approved by the FDA for the treatment of three types of rheumatoid immune diseases, and …

cyclosporine
dermatomyositis
methotrexate
glucocorticoids
tacrolimus
  • 0 views
  • 09 Jul, 2021
  • 1 location
National Registry for Egyptian Pediatric Neuromuscular Diseases

Our aim is to establish multi-center national Egyptian database of information for inherited and acquired neuromuscular diseases in infants and children from 0 to 18 years of age.

nerve conduction study
weakness
neuromuscular diseases
  • 13 views
  • 08 Nov, 2020
  • 1 location
Immune Related-adverse Events in Patients Receiving Immune Checkpoint Inhibitors

The recent introduction of anti-PD-1 (nivolumab and pembrolizumab) and anti- PD-L1 (atezolizumab, durvalumab, avelumab) immune checkpoint inhibitors revolutionized oncological guidelines. Durable responses and prolongation of survival with these agents come at the price of the development of immune related adverse events (irAEs). Innovative tools are required in order to manage …

atezolizumab
pembrolizumab
lymphoma
carcinoma
nivolumab
  • 3 views
  • 23 Jan, 2021
  • 2 locations
The Clinical Course of Interstitial Pneumonia With Autoimmune Features

Interstitial pneumonia with autoimmune features (IPAF) is a chronic interstitial lung disease (ILD) with some laboratoristic and/or clinical features of autoimmune disease, but without meeting criteria of connective tissue disease (CTD), and with no other causes of ILD. Despite recent efforts to standardize the diagnosis of IPAF, subjects with IPAF …

  • 4 views
  • 12 Mar, 2021
  • 1 location
Manganese-Enhanced Magnetic Resonance Imaging (MEMRI) in Ischaemic Inflammatory and Takotsubo Cardiomyopathy (MEMORY)

Manganese is a calcium analogue which actively enters viable cells with intact calcium-handling mechanisms and its uptake is evident by an increase in MRI-detectable T1 relaxivity of tissues. Mangafodipir is a novel manganese-based magnetic resonance imaging (MRI) contrast medium with unique biophysical properties that are ideal for application to cardiac …

  • 27 views
  • 27 Jan, 2021
  • 1 location