Idiopathic Inflammatory Myopathies Clinical Trials

A listing of Idiopathic Inflammatory Myopathies medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 64 clinical trials
Assessment of Safety and Acute Effects of a Lower-limb Powered Dermoskeleton in Patients With Neuromuscular Disorders (Exo-KGO1)

The aims of the current study are as follow: i) Evaluate the safety, usability, and acute efficiency of a programmable ambulation exoskeleton (KeeogoTM Dermoskeleton System, B-Temia Inc., Quebec, Canada) in patients with neuromuscular disorders, ii) Elaborate recommendations regarding usability criteria for safe and efficient use the device in patients with …

respiratory assessment
Accepts healthy volunteers
myopathy
  • 0 views
  • 24 Apr, 2022
  • 1 location
Assessment of Safety and Acute Effects of a Knee-hip Powered Soft Exoskeleton in Patients With Neuromuscular Disorders (Exo-NMD1)

The aims of the current study are as follow: i) Evaluate the safety, usability, and acute efficiency of a powered knee-hip dermoskeleton (MyoSuit, MyoSwiss, Zurich, Switzerland) in patients with neuromuscular disorders, ii) Elaborate recommendations regarding usability criteria for safe and efficient use the device in patients with neuromuscular disorders (e.g. …

myopathy
Accepts healthy volunteers
respiratory assessment
  • 0 views
  • 25 Mar, 2022
  • 1 location
Clinical Study of MMF in Treatment of IIM-ILD and Its Effect on Peripheral Blood Treg Cells

Interstitial lung disease (ILD) is a common pulmonary manifestation of idiopathic inflammatory myopathy (IIM). The overall 5-year mortality is 50%. The prognosis is poor and the treatment is

pulmonary fibrosis
lupus
tacrolimus
azathioprine
myopathy
  • 0 views
  • 30 Nov, 2021
  • 1 location
Exercise Capacity of Patients With Dermatomyosis

Dermatomyositis (DM) patients experience muscle weakness and low aerobic capacities, which are associated with poor health status and increased mortality. The origin of this muscle impairment remains unknown. The investigators hypothesize that mitochondria functioning is impaired in DM muscle and links with exercise capacities.

creatine kinase
polymyositis
myopathy
weakness
muscle biopsy
  • 0 views
  • 19 Sep, 2021
  • 1 location
Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study (ITS-PILOT)

Ectopic soft tissue calcifications or ossifications can complicate the course of numerous diseases; most of them are rare or very rare. Even if the clinical, radiological and pathological presentation of ectopic calcifications and ossifications are different, the same hypotheses are discussed considering their hypothetical pathophysiology. Indeed, high calcium phosphate product, …

progressive systemic sclerosis
computerized tomography
parathyroid hormone
calcium
dermatomyositis
  • 12 views
  • 24 Mar, 2022
  • 3 locations
Single Escalating Dose Pilot Trial of Canakinumab (ILARIS®) in Duchenne Muscular Dystrophy

serum biomarkers in a sample of young boys with DMD who are most likely to have high levels of muscle inflammation. Steroid naive DMD subjects aged greater than or equal to 2 years old to less than 6

muscular dystrophy
glucocorticoids
duchenne muscular dystrophy
  • 21 views
  • 12 Mar, 2022
  • 1 location
Cyclophosphamide and Azathioprine vs Tacrolimus in Antisynthetase Syndrome-related Interstitial Lung Disease

"Antisynthetase syndrome (ASS) is one of the most severe inflammatory myopathy (IM), due to pulmonary involvement (interstitial lung disease, ILD). Until now, the most commonly used

  • 0 views
  • 15 Feb, 2021
  • 1 location
Impacts of Mitochondrial-targeted Antioxidant on Peripheral Artery Disease Patients

systemic and skeletal muscle inflammation due to the impaired oxygen transfer capacity of these blood vessels. This attenuated oxygen transfer capacity causes hypoxic conditions in the skeletal muscle and

cardiovascular disease
treadmill test
peripheral arterial diseases
diabetes
intermittent claudication
  • 5 views
  • 01 Jul, 2022
  • 1 location
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced, Metastatic, or Unresectable Cancer

This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's …

dermatomyositis
cancer
diabetes mellitus (dm)
ct scan
neutrophil count
  • 995 views
  • 28 Jul, 2022
  • 33 locations
Immunosuppressant Combined With Pirfenidone in CTD-ILD

A prospective cohort study was used to observe the efficacy and safety of different immunosuppressive agents with/wo pirfenidone on CTD-ILD patients in Qilu Hospital of Shandong University for 36 months.The main research endpoints are lung function, patient dyspnea score, 6-minute walking distance, imaging indicators, primary disease activity, adverse reactions, etc.

progressive systemic sclerosis
dyspnea
pirfenidone
rheumatism
immunosuppressive
  • 0 views
  • 24 Jun, 2021
  • 1 location