Idiopathic Inflammatory Myopathies Clinical Trials

A listing of Idiopathic Inflammatory Myopathies medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 60 clinical trials
Abatacept for the Treatment of Myositis-associated Interstitial Lung Disease

A randomized, controlled pilot trial to evaluate the efficacy and safety of subcutaneous Abatacept in treating interstitial lung disease associated with the anti-synthetase syndrome.

igiv
tumor necrosis factor
intravenous immunoglobulin
tacrolimus
azathioprine
  • 188 views
  • 18 Apr, 2021
  • 5 locations
Exercise Creatine and Coenzyme Q10 for Childhood Myositis

Children with JDM are weak and get tired because their muscles aren't able to work like healthy muscles. This can make it hard for them to do normal everyday things and can make them less happy about their lives compared to children without the disease. There are two nutritional supplements …

  • 0 views
  • 06 May, 2021
  • 1 location
A Phase 1 Study of ABC008 in Adult Patients With Inclusion Body Myositis (IBM)

An open-label, ascending dose study for adult patients with inclusion body myositis (IBM).

inclusion body myositis
  • 0 views
  • 07 Jul, 2021
  • 1 location
Influence of Aerobic Training and Weight Loss on Skeletal Muscle Inflammatory Markers and Muscle Protein Balance in Older Adults

lifestyle modification via weight loss and aerobic exercise can reduce skeletal muscle inflammation and subsequently improve nutrient-stimulated muscle protein synthesis in previously sedentary, obese older

cancer
TACE
tumor necrosis factor
cytokines
aerobic exercise
  • 94 views
  • 22 Jan, 2021
  • 1 location
Effects of High-intensity Interval Training (HIIT) in Recent Onset Polymyositis and Dermatomyositis

Polymyositis and dermatomyositis are rare inflammatory systemic conditions. Reduced muscle function is a cardinal symptom and lung involvement is very common. Knowledge of heart involvement in these patients is very limited, as is knowledge of exercise effects in recent onset, active disease. The aim of this project is to investigate …

polymyositis
cancer
depression
high-intensity interval training
strength training
  • 18 views
  • 22 Jan, 2021
  • 1 location
Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis

Background Dermatomyositis (DM) and juvenile dermatomyositis (JDM) cause inflammation in the muscles. People with DM and JDM can develop calcium deposits in places they should not, known as calcinosis. Calcinosis can be painful and cause disabilities and other problems. Researchers want to learn more about calcinosis to find treatments for …

igiv
juvenile dermatomyositis
creatine kinase
dermatomyositis
kidney ultrasound
  • 76 views
  • 21 Sep, 2021
  • 1 location
Phase 1 Study of ULSC in Patients With Polymyositis (PM) and Dermatomyositis (DM)

This study will investigate Umbilical Cord Lining Stem Cells (ULSC) as an investigational medicinal product and its use in patients with polymyositis (PM) or dermatomyositis (DM) to see if a single intravenous (IV) infusion of allogeneic umbilical cord lining stem cells (ULSC) safe, tolerable, and feasible to administer.

polymyositis
dermatomyositis
  • 0 views
  • 08 Aug, 2021
  • 1 location
Exercise Capacity of Patients With Dermatomyosis

Dermatomyositis (DM) patients experience muscle weakness and low aerobic capacities, which are associated with poor health status and increased mortality. The origin of this muscle impairment remains unknown. The investigators hypothesize that mitochondria functioning is impaired in DM muscle and links with exercise capacities.

polymyositis
weakness
myopathy
muscle biopsy
dermatomyositis
  • 0 views
  • 19 Sep, 2021
  • 1 location
Subcutaneous Injection of Sodium Thiosulfate for Ectopic Calcifications or Ossifications. A Pilot Study

Ectopic soft tissue calcifications or ossifications can complicate the course of numerous diseases; most of them are rare or very rare. Even if the clinical, radiological and pathological presentation of ectopic calcifications and ossifications are different, the same hypotheses are discussed considering their hypothetical pathophysiology. Indeed, high calcium phosphate product, …

calcium
parathyroid hormone
progressive systemic sclerosis
computerized tomography
dermatomyositis
  • 12 views
  • 25 Jan, 2021
  • 5 locations
Single Escalating Dose Pilot Trial of Canakinumab (ILARIS ) in Duchenne Muscular Dystrophy

serum biomarkers in a sample of young boys with DMD who are most likely to have high levels of muscle inflammation. Steroid naive DMD subjects aged greater than or equal to 2 years old to less than 6

glucocorticoids
muscular dystrophy
  • 21 views
  • 04 Mar, 2021
  • 1 location