Idiopathic Inflammatory Myopathies Clinical Trials

A listing of Idiopathic Inflammatory Myopathies medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 9 clinical trials
Novel PET Radioligands as Inflammatory Biomarkers in Rheumatoid Arthritis and Myositis

18 and older with rheumatoid arthritis or idiopathic inflammatory myopathy (IIM). Healthy volunteers enrolled in protocol 01-M-0254 or 17-M-0181 are also needed. Design

nonsteroidal anti-inflammatory drugs
weakness
arthritis
myopathy
MRI
  • 36 views
  • 30 Jul, 2021
  • 1 location
Phase 1 Study of ULSC in Patients With Polymyositis (PM) and Dermatomyositis (DM)

This study will investigate Umbilical Cord Lining Stem Cells (ULSC) as an investigational medicinal product and its use in patients with polymyositis (PM) or dermatomyositis (DM) to see if a single intravenous (IV) infusion of allogeneic umbilical cord lining stem cells (ULSC) safe, tolerable, and feasible to administer.

  • 0 views
  • 01 Aug, 2021
  • 1 location
Sodium Thiosulfate for Treatment of Calcinosis Associated With Juvenile and Adult Dermatomyositis

Background Dermatomyositis (DM) and juvenile dermatomyositis (JDM) cause inflammation in the muscles. People with DM and JDM can develop calcium deposits in places they should not, known as calcinosis. Calcinosis can be painful and cause disabilities and other problems. Researchers want to learn more about calcinosis to find treatments for …

kidney ultrasound
diabetes
calcium
blood tests
dermatomyositis
  • 76 views
  • 01 Aug, 2021
  • 1 location
A Study In Adults With Moderate To Severe Dermatomyositis

A Study looking at Investigational drug and Placebo administered to adult Patients with moderate to severe Dermatomyositis

rash
experimental drug
corticosteroids
dermatomyositis
  • 122 views
  • 30 Jul, 2021
  • 32 locations
Nivolumab in Treating Patients With Autoimmune Disorders and Advanced Metastatic or Unresectable Cancer

This phase Ib trial studies the side effects of nivolumab and to see how well it works in treating patients with autoimmune disorders and cancer that has spread to other places in the body or cannot removed by surgery. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's …

computed tomography
nivolumab
solid tumor
lymphoma
glomerular filtration rate
  • 609 views
  • 01 Aug, 2021
  • 28 locations
Adult and Juvenile Myositis

inflammatory muscle disease that can damage muscles and other organs, resulting in significant disability. Children or adults with polymyositis or dermatomyositis or a related condition may be

chest x-ray
polymyositis
pulmonary function test
cancer
MRI
  • 56 views
  • 01 Aug, 2021
  • 2 locations
Study and Treatment of Inflammatory Muscle Diseases

This study of inflammatory muscle diseases-polymyositis and dermatomyositis and related disorders-will examine what causes these diseases and describe the clinical features (signs and symptoms

polymyositis
biopsy incision
pulmonary function test
MRI
dermatomyositis
  • 803 views
  • 27 Jul, 2021
  • 1 location
Studies of the Natural History Pathogenesis and Outcome of Autoinflammatory Diseases Including Juvenile Dermatomyositis

Purpose The purpose of this protocol is 1. To comprehensively evaluate patients with autoinflammatory diseases clinically, genetically and immunologically at the autoinflammatory disease clinic at the NIH. 2. To follow patients with autoinflammatory Diseases that are genetically defined including Neonatal-Onset Multisystem Inflammatory Disease (NOMID), the most severe clinical phenotype of …

skin disease
deficiency
blood tests
il-1
dermatomyositis
  • 497 views
  • 28 Jul, 2021
  • 1 location
Environmental Risk Factors for the Anti-synthetase Syndrome

autoimmune disorder myositis weakens the muscles and may cause other health problems. Environmental exposures associated with myositis include ultraviolet radiation, stressful life events and muscle

chest x-ray
autoimmune disease
pulmonary function test
white blood cells
house dust
  • 142 views
  • 01 Aug, 2021
  • 5 locations