Dermatomyositis (Connective Tissue Disease) Clinical Trials

A listing of Dermatomyositis (Connective Tissue Disease) medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 28 clinical trials
Natural History Pathogenesis and Outcome of Melorheostosis A Rare Osteosclerotic Disease

Background The rare disease melorheostosis causes bones to thicken. This may lead to pain, and can affect bones, joints, and muscles. Researchers want to learn more about the disease and how it progresses. Objective -To see what happens to people with melorheostosis over time and understand the causes of the …

x-rays
probe
melorheostosis
urine test
electrical shock
  • 15 views
  • 15 Sep, 2021
  • 1 location
Assessment of Nutritional Status in Systemic Sclerosis

The main theme of the cohort of systemic sclerosis (SSc) patients is the determination of nutritional status, its evolution and the evaluation of its management in patients with scleroderma. The main objectives are : To determine the incidence of malnutrition and its main determinants (disease characteristics, severity, eating habits, physical …

rheumatism
progressive systemic sclerosis
scleroderma
pulmonary function test
  • 42 views
  • 08 Sep, 2021
  • 1 location
Volatile Organic Compounds (VOCs) as a Biomarker in Immune-mediated Pulmonary Arterial Hypertension (PAH)

Aim: to investigate the role of inflammation and auto-immunity in pulmonary arterial hypertension by using the profile of volatile organic compounds. Hypothesis: first, the investigators hypothesize that at time of diagnosis the VOC profiles will discriminate patients with PAH-CTD and idiopathic PAH (IPAH) from patients with systemic sclerosis or systemic …

rheumatism
progressive systemic sclerosis
lupus
connective tissue disease
hypertension
  • 1 views
  • 15 Sep, 2021
  • 1 location
Environmental Risk Factors for the Anti-synthetase Syndrome

Background Like other complex diseases, autoimmune diseases are the result of numerous causes, including genetic and environmental factors. Some researchers believe that people who are susceptible to autoimmune disorders develop them when the body reacts to environmental or other factors by creating white blood cells that attack the body s …

connective tissue disorder
white blood cells
house dust
chest x-ray
autoimmune disease
  • 142 views
  • 12 Sep, 2021
  • 5 locations
Post-contracture Release Radiation for Dupuytren's Disease

To determine if the clinical impression of clinicians, ie that patients are improving with the current treatment pathway for Dupuytren's (contracture release followed by radiation), can be substantiated with scientific evidence.

dupuytren's contracture
  • 50 views
  • 10 Sep, 2021
  • 1 location
New Orleans Pulmonary Hypertension Biobank

Pulmonary hypertension (PH) is a serious condition characterized by a mean pulmonary artery pressure >=25mmHg on right heart catheterization (RHC). Despite advances in PH care, outcomes are still sub-optimal and further research is required into the pathobiology of the disease and development of biomarkers that can guide clinical care. The …

rheumatism
right heart catheterization
progressive systemic sclerosis
mixed connective tissue disease
hypertension
  • 102 views
  • 15 Sep, 2021
  • 1 location
Clinical Genetic and Epidemiologic Study of Children and Adults With RASopathies

Background The RASopathies are a clinically defined group of disorders caused by germline mutations in genes encoding components of the Ras/mitogen-activated-protein kinase (Ras/MAPK) pathway. These disorders have overlapping clinical features due to Ras/MAPK dysfunction, including a predisposition to the development of certain malignancies. The aims of this prospective longitudinal cohort …

  • 0 views
  • 15 Sep, 2021
  • 1 location
The Personalised Antibiotic Duration for Cellulitis (PAD-C) Study

Cellulitis is an increasingly common and unpleasant bacterial infection of the skin, usually affecting the legs. Patients experience pain and swelling, loss of mobility, fever, and chills. Patients may be left with chronic skin damage and 1 in 5 experience recurrences. Cellulitis is treated with antibiotics, but it is unclear …

  • 0 views
  • 12 Sep, 2021
  • 1 location