Saliva and Salivary Gland Dysfunction Clinical Trials

A listing of Saliva and Salivary Gland Dysfunction medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 9 clinical trials
An Open-Label, Multicenter, Global Phase 2 Basket Study of Entrectinib for the Treatment of Patients With Locally Advanced or Metastatic Solid Tumors That Harbor NTRK1/2/3, ROS1, or ALK Gene Rearrangements (STARTRK-2)

This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor an NTRK1/2/3, ROS1, or ALK gene fusion. Patients will be assigned to different baskets according to tumor type and gene fusion.

cancer treatment
proto-oncogene tyrosine-protein kinase ros
gene fusion
leptomeningeal carcinomatosis
  • 25 Oct, 2022
  • 9 locations
Interest of Auriculotherapy in the Treatment of Xerostomia (AURICULOXERO)

The aim of the study is to show that auriculotherapy is effective in the treatment of xerostomia

  • 25 Mar, 2022
  • 3 locations
Blinded Dry Mouth Spray Crossover Study

To identify the effectiveness of two mouth sprays at relieving symptoms of xerostomia in patients who have received radiation for carcinoma of the head and neck. To assess patient quality of life and mouth acidity following use of two mouth sprays meant to relieve symptoms of xerostomia in patients who …

  • 04 Oct, 2022
  • 2 locations
Binary Oncolytic Adenovirus in Combination With HER2-Specific Autologous CAR VST, Advanced HER2 Positive Solid Tumors (VISTA)

This study is a first in human Phase 1 study that involves patients with a type of cancer called HER2 (Human Epidermal Growth Factor Receptor 2) positive cancer. This study asks patients to volunteer to take part in a research study investigating the safety and efficacy of using special immune …

pancreatic adenocarcinoma
absolute neutrophil count
growth factor
bladder cancer
  • 07 Oct, 2022
  • 1 location
Characterization of Diseases With Salivary Gland Involvement

Background Salivary glands in and around the mouth and throat make saliva. Salivary gland disorders can affect a person s quality of life. Studying people who have a disease that affects their salivary gland(s) may teach researchers about the disorders and their genetics. Objectives To study salivary gland diseases and …

Accepts healthy volunteers
cancer treatment
dry eyes
  • 27 Oct, 2022
  • 1 location
Validation of the French Version of the Xerostomia Inventory (XIvf)

The main objective of this study is to achieve cross-cultural and psychometric validation of the Xerostomia Inventory initially developed in English language into French Language. This will be achieved in two stages: First, cross-cultural validation, and a second, psychometric validation The cross-cultural validation will be performed according to the methodology …

Accepts healthy volunteers
  • 24 Feb, 2022
  • 1 location
The Pathogenesis and Natural History of Sjogren's Syndrome

Background -Sjogren s syndrome is a disease that affects about 1-4 million Americans. It is more common in women. It mainly affects the glands that produce saliva and tears, leading to dry eyes and dry mouth. The cause of Sjogren s syndrome is unknown, but inflammation plays an important role. …

dry eyes
keratoconjunctivitis sicca
  • 21 Oct, 2022
  • 1 location
Immunohistochemical & Immunoblot Analysis of NIS (Na+/I-Symporter) in Archival & Frozen Tissue Sample

The goal of this study is to study NIS expression in benign and malignant breast and thyroid samples using archival formalin-fixed paraffin-embedded tissue sections.

  • 05 Jul, 2022
  • 1 location
Exploratory Study of Molecular Profile-Associated Evidence Guided Precision Therapy for Salivary Gland Cancer MAPS

To explore the feasibility, efficacy and safety of determining the treatment regimen based on genomic profiling in patients with locally advanced and advanced salivary gland cancer.

  • 28 Oct, 2021
  • 1 location