Alpha 1 Antitrypsin Deficiency Clinical Trials
A listing of Alpha 1 Antitrypsin Deficiency medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.
Found 22 clinical trials
Alpha-1 Study: A research study for individuals with Alpha-1 Antitrypsin Deficiency
The Alpha-1 Study is a clinical research study currently enrolling individuals 18 to 78 (inclusive) with Alpha-1 Antitrypsin Deficiency. The purpose of this study is to evaluate
- 240 views
- 23 Nov, 2020
- 7 locations
Role of Genetic Factors in the Pathogenesis of Lung Disease
This study is designed to evaluate the genetics involved in the development of lung disease by surveying genes involved in the process of breathing and examining the genes in lung cells of patients with lung disease. The study will focus on defining the distribution of abnormal genes responsible for processes …
- 358 views
- 23 Nov, 2020
- 1 location
A Study of Belcesiran in Patients With A1ATD-Associated Liver Disease (ESTRELLA)
This is a multiple dose, randomized, placebo-controlled, double-blind study of belcesiran to evaluate the safety, tolerability, PK, and PD in adult patients with PiZZ A1ATD-associated liver
- 2 views
- 04 Oct, 2022
- 14 locations
A Study to Evaluate Efficacy and Safety of VX-864 in Participants With the PiZZ Genotype
The purpose of this study is to evaluate the efficacy and safety of VX-864 in participants with the PiZZ genotype over 48 weeks.
- 0 views
- 18 Sep, 2023
- 8 locations
Study of INBRX-101 Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema (ELEVAATE)
Phase 2 study to compare INBRX-101 to plasma derived A1PI therapy in adults with AATD emphysema
- 0 views
- 18 Sep, 2023
- 5 locations
A Phase 1, First-in-human Study of VX-668
The purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics (PK) of VX-668 at various doses.
- 0 views
- 08 Sep, 2023
- 5 locations
Hyperpolarized 129Xe MR Imaging of the Lung Function in Healthy Volunteers and Subjects With Pulmonary Disease
The purpose of this study is to develop and evaluate the usefulness of MRI using 129Xe gas for regional assessment of pulmonary function. Specifically, three forms of 129Xe MRI contrast will be the investigators focus - 1) imaging of the 129Xe ventilation distribution, 2) imaging the alveolar microstructure via the …
- 288 views
- 24 Oct, 2022
- 1 location
An Observational Study Evaluating Patients With Chronic Liver Diseases Associated With Hepatic Steatosis (FALL)
other chronic liver diseases like autoimmune hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, hereditary hemochromatosis and alpha-1-antitrypsin deficiency and may also develop
- 0 views
- 29 Apr, 2022
- 1 location
EARCO REGISTRY. History Of Patients With Alpha-1 Antitrypsin (EARCO)
European Alpha-1 Research Collaboration (EARCO) is a pan-European network committed to promoting clinical research and education in alpha-1 antitrypsin deficiency (AATD). The core project is the
- 22 views
- 26 Feb, 2022
The Alpha-1 Foundation's and University of Florida's Alpha-1 Coded Testing (ACT) Study (ACT)
The Alpha-1 Coded Testing (ACT) Study was established to study genetic testing and outcomes of individuals at risk for alpha-1 antitrypsin deficiency.
- 186 views
- 05 Sep, 2023
- 1 location