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Alpha 1 Antitrypsin Deficiency Clinical Trials

A listing of Alpha 1 Antitrypsin Deficiency medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

RESULTS

Found (382) clinical trials

The study aims to evaluate The effect of oral (PO) CC-90001, administered once daily (QD), compared with placebo, will be evaluated in subjects with NASH and Stage 3 fibrosis and explored in subjects with NASH and Stage 4 fibrosis. This study is designed to assess response to treatment on measures ...

Phase

A research study is evaluating an investigational blood sample diagnostic test combined with liver ultrasounds, compared to ultrasounds alone, for the detection of liver cancer in people with liver cirrhosis.  

Phase N/A

Nonalcoholic steatohepatitis (NASH) is liver inflammation caused by a buildup of fat in the liver. ClinSearch is enrolling volunteers with a condition called liver fibrosis from NASH in a study testing the effectiveness and safety of an investigational medication.   Qualified participants may receive: -  Study-related medication at no cost-  Study-related medical ...

Phase N/A

A research study is evaluating an investigational medication that may slow the progression of alpha-1 antitrypsin deficiency in patients with emphysema.

In this research study, there are two study phases. In the first phase which last one year, eligible NASH participants will be assigned to receive the investigational drug OCA or placebo. The study treatment will be assigned randomly (like flipping a coin) with two-thirds of the participants assigned to OCA ...

Phase

This is a multicenter, randomized, double-blind, placebo-controlled, dose-ranging study to evaluate the safety, including tolerability, of ISIS 703802 and to assess the efficacy of different doses and dosing regimens of ISIS 703802 on glucose and lipid metabolism, and liver fat in subjects with Hypertriglyceridemia, Type 2 Diabetes Mellitus (T2DM), and ...

Phase

Clinical Trials of Texas, Inc. is conducting a research study of an investigational medication for participants. Qualified participants receive study-related medical care from a board-certified physician, study medications, supplies and exams.

Phase N/A

The primary objectives of this study are to evaluate the effect of Obeticholic Acid treatment compared to placebo on 1) histological improvement and 2) liver-related clinical outcomes in patients with non-cirrhotic nonalcoholic steatohepatitis (NASH) with liver fibrosis.

Phase N/A

People with liver disorder are asked to participate in a research study being conducted by Montefiore Medical Center.

Phase N/A

Clinical Trials of Texas, Inc. is enrolling now for an investigational medication for patients with non-alcoholic fatty liver disease. Study participation is approximately 98 days. Qualified participants will receive study-related medical care from a board-certified physician, study medications, exams and evaluations. Qualified participants will help further medical science for treatment ...

Phase N/A