Sjogren's syndrome Clinical Trials

A listing of Sjogren's syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 111 clinical trials
A Study of the Drugs AGN-242428 and AGN-231868 in Participants With Dry Eye Disease

This will be a 2 stage study in which Stage 1 will evaluate the safety of AGN-242428 and AGN-231868, how well they are tolerated and how they move through the body when administered. After the sponsor's determination of adequate safety and tolerability of the interventions in Stage 1, Stage 2 …

eye disease
schirmer's test
  • 30 Dec, 2021
  • 13 locations
Rexon-Eye in Dry Eye

Resono Ophthalmic has developed Rexo-Eye in 2014, a QMR-based patented instrument which is hypothesised to stimulate physiological cellular regeneration and reactivate the tear system by stimulating and reactivating the lacrimal system, induce mild hyperthermia and massage effects which reactivate the tear and lipid secretion, targeting all arms of pathogenic mechanisms …

artificial tears
ophthalmic solution
eye disease
  • 01 Oct, 2021
  • 1 location
Effect of Cequa in Subjects With Dry Eye Disease

This is a Phase 4, multicenter, single arm, 12 week study in subjects with dry eye disease, which is inadequately controlled by cyclosporine 0.05% ophthalmic emulsion.

cyclosporine 0.05% ophthalmic emulsion
cyclosporine ophthalmic emulsion
corrected visual acuity
ophthalmic solution
  • 25 Nov, 2021
  • 5 locations
Intracanalicular Dexamethasone Insert for the Treatment of Inflammation and Discomfort in Dry Eye Disease (DEcIDED)

This prospective, single-center, randomized, double-masked, parallel comparison, sponsored study seeks to investigate the efficacy of Intracanalicular dexamethasone Insert (IDI) on ameliorating the signs and symptoms of dry eye disease.

confocal microscopy
eye disease
  • 15 Nov, 2021
  • 1 location
Study to Evaluate Efficacy and Safety of Selective Internal Radiation Therapy Plus Xelox Bevacizumab and Atezolizumab (Immune Chekpoint Inhibitor) in Patients With Liver-dominant Metastatic Colorectal Cancer

The main objective of the SIRTCI study is to evaluate the safety and efficacy of the combination chemotherapy (XELOX: Capecitabine plus oxaliplatin), anti-angiogenic (Bevacizumab), SIRT (TheraSphere) and ICI (Atezolizumab) in patients with CRC with predominant liver metastases. SIRTCI is a single-arm, prospective, multi-centre phase II study. The main inclusion criteria …

  • 27 Jan, 2021
  • 1 location
Dry Eye OmniLenz Application of Omnigen Research Study

Dry eye disease (DED) is a disease of the ocular surface characterised by ocular surface inflammation and damage and neurosensory abnormalities. Tear film breakup leading to localised hyperosmolarity can result in ocular surface damage either directly or through the cascade of inflammation that it initiates. Transplantation of human amniotic membrane …

  • 22 Nov, 2021
  • 1 location
Wireless Micropump in Dry Eye Patients

The purpose of this study is to carry out a trial to get more convincing and valuable results of the wireless micropump in dry eye patients and compare the outcomes before and after eye drops usage. The investigators hope to investigate the micropump comprehensively, including the comparison of tear film …

  • 27 Jan, 2021
  • 1 location
Safety and Efficacy of Dexamethasone Ophthalmic Insert (Dextenza ) in the Management of Clinically Significant Dry Eye

To determine efficacy and safety profile of dexamethasone 0.4mg lacrimal insert in dry eye related ocular surface inflammation.

  • 26 Mar, 2021
  • 1 location
Effects of Topical Insulin on Levels of Tear Inflammatory Mediators

60 samples are take to determine the effects of topical insulin on tear inflammatory mediators interleukin 1a, interleukin 6 and matrix metalloprotenase 9 in diabetics with dry eye disease.

  • 16 May, 2021
  • 1 location
Prospective Randomized Masked Controlled Trial To Evaluate The Safety And Effectiveness Of The TearCare System In The Treatment Of The Signs And Symptoms Of Dry Eye Disease (SAHARA)

To demonstrate the safety and effectiveness of TearCare procedures compared to Restasis to treat the signs and symptoms of dry eye disease in adult patients.

  • 14 May, 2021
  • 14 locations