Sjogren's syndrome Clinical Trials

A listing of Sjogren's syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
I am looking for
added new label for I am looking for
Advanced Filters
Found 111 clinical trials
A Study to Evaluate the Efficacy and Safety of Iguratimod Compared to Placebo in Patients With Active Primary Sjogren's Syndrome.

The purpose of this study is to evaluate the efficacy and safety of iguratimod compared to placebo in patients with active primary Sjogren's Syndrome.

  • 29 Jul, 2021
  • 30 locations
Tivanisiran for Dry Eye in Subjects With Sj gren's Syndrome

This study will examine the efficacy and safety of tivanisiran sodium eye drops versus vehicle after a 2-week run-in phase when dosed once daily for 3 months in subjects with signs and symptoms of dry eye disease (DED) due to Sjgren's Syndrome.

  • 29 Sep, 2021
  • 30 locations
Mesenchymal Stem Cell Therapy of Dry Eye Disease in Patients With Sj gren's Syndrome

AMASS is a double-blinded randomized clinical trial with the purpose of investigating whether injection of allogeneic adipose-derived mesenchymal stem cells (ASCs) into the lacrimal gland (LG) results in increased ocular comfort compared to placebo.

  • 23 Sep, 2021
  • 1 location
Clinical Study of Jianfei Kangfu Cao in the Treatment of pSS-ILD

This study will evaluate the safety and efficacy of Jianfei Kangfu Cao in the treatment of primary Sjogren's syndrome associated interstitial lung disease.

  • 07 Mar, 2021
  • 1 location
  • 21 Jan, 2022
RElevance of UltraSonography for Assessing Salivary Gland Involvement in Systemic Sclerosis (SSc)

As fibrosis of salivary glands is supposed to be the main mechanism involved in Systemic sclerosis (SSc)-associated sicca syndrome, Ultrasonography , biopsy and measuring gland elasticity (by

  • 24 Nov, 2021
  • 3 locations
Intravenous Immunoglobulins for the Treatment of Primary Sj gren's Syndrome Associated Painful Sensory Neuropathies

To summarise, the peripheral neurological complications experienced by patients with primary Sjgren's syndrome are particularly bothersome since they are common and often result in significant disability related to pain or motor impairment. There is currently no standard treatment for these patients. As these neuropathies are caused by an immune system …

  • 08 Sep, 2021
  • 1 location
Tyrosine Kinase Inhibitor (TKI) + Anti-PD-1 Antibody in TKI-responded Microsatellite Stability/Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Adenocarcinoma.

The purpose of this study is to evaluate the efficacy and safety of fruquintinib or regorafenib in combination with anti-PD-1 antibody in TKI (fruquintinib or regorafenib)-responded MSS/pMMR metastatic colorectal adenocarcinoma.

  • 10 Oct, 2021
  • 1 location
CDSS of Traditional Chinese Medicine Intervention for Dry Eye Syndrome

This project is based on artificial intelligence (AI) algorithms to screen the effective methods of traditional Chinese medicine intervention for dry eye and its applicable conditions, and optimize the traditional Chinese medicine intervention plan for dry eye through the evaluation of evidence-based medicine and expert consensus, and construct the Clinical …

  • 27 Mar, 2021
  • 1 location
3 Month Study of Alocross Versus Vismed in Adults With Dry Eye Disease Related to Keratitis or Keratoconjunctivitis

This study is a prospective, multicentre, parallel-group, active-controlled, non-inferiority study conducted in adult patients with moderate-to-severe dry eye disease (DED) related to keratitis or keratoconjunctivitis. This study is conducted at a national level, in France. The patients will be randomised to receive ALOCROSS or the reference treatment, VISMED (ratio 1:1) …

  • 24 Jun, 2021
  • 10 locations