Sjogren's syndrome Clinical Trials

A listing of Sjogren's syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 193 clinical trials
Gut Microbiome and Sex as Risk Factors for Kidney Stones After Bariatric Surgery

This is a single-center study that aims to better understand how diet and sex affect the risk of kidney stones in people who have had gastric bypass surgery. Subjects will be asked to follow a special (clinic-provided) diet for six days and come to a research clinic for 3 study …

  • 11 May, 2021
  • 1 location
Comparison of the Effects of Different Manual Therapy Techniques in Patients With Cervical Spondylosis

Proprioceptive sensitivity decreases in individuals with neck pain compared to those without neck pain. While organizing the treatment program of patients with neck pain, evaluation of cervical proprioception and its addition to the treatment have gained importance. The aim of the study is to examine the effects of muscle energy …

  • 12 Mar, 2021
  • 1 location
A Clinical Trial on the Failure Rates of Metallic and Ceramic Orthodontic Brackets

The aim of this study is to assess if there are significant differences in the failure rate of stainless steel and ceramic brackets. For this study, patients will be enrolled and divided into two groups, according to the type of brackets (stainless steel or ceramic) used for orthodontic treatment. Failure …

  • 06 Jan, 2022
  • 1 location
Targeting Reactive Oxygen Species Production as a Novel Therapeutic in Fuch's Endothelial Corneal Dystrophy

This protocol will investigate whether topical application of N-acetyl cysteine (NAC) eye drops decreases oxidative stress and confers cytoprotection in patients with FECD.

  • 17 Oct, 2021
  • 1 location
Metabolomics: A Novel Tool for Investigating the Pathogenesis of Age-related Macular Degeneration

The global aim of this project is to expand the knowledge on the multifactorial pathogenesis of AMD. In addition to age, the multifactorial pathogenesis of AMD includes environmental and genetic risk factors. However, how these interact to promote progression remains largely unknown. AMD is a progressive retinal disease characterized by …

geographic atrophy
  • 08 Jul, 2021
  • 1 location
A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

The purpose of this study is to evaluate the efficacy and safety of nipocalimab in participants with primary Sjogren's syndrome (pSS) versus placebo.

  • 04 Jan, 2022
  • 24 locations
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sj gren's Syndrome

This study will evaluate safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of CFZ533 (iscalimab) in patients with Sjgren's Syndrome.

  • 08 Dec, 2021
  • 76 locations
A Study to Evaluate the Efficacy and Safety of VIB4920 in Participants With Sj gren's Syndrome

The purpose of the study is to evaluate the efficacy, safety, and tolerability of VIB4920 (formerly MEDI4920) in adult participants with Sjgren's Syndrome (SS).

  • 07 Oct, 2021
  • 54 locations
Safety Tolerability Pharmacokinetics and Therapeutic Efficacy of SAR441344 in Primary Sj gren's Syndrome (pSjS)

Primary Objective: To evaluate the therapeutic efficacy of one dose level of SAR441344 versus placebo over 12 weeks in adult patients with primary Sjgren's syndrome (pSjS), assessed by the change of the European League Against Rheumatism (EULAR) Sjgren's Syndrome Disease Activity Index (ESSDAI) Secondary Objectives: To evaluate the therapeutic efficacy …

  • 02 Dec, 2021
  • 60 locations
Study of Safety and Tolerability of CFZ533 in Patients With Sj gren's Syndrome

This study will evaluate the safety and tolerability of iscalimab at two dose levels in patients with Sjgren's Syndrome, who participated in the TWINSS core study, CCFZ533B2201(NCT03905525). Additionally, this Extension study will further explore the pharmacokinetics (PK) and efficacy of iscalimab at two dose level.

  • 11 Dec, 2021
  • 18 locations