Sjogren's syndrome Clinical Trials

A listing of Sjogren's syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 66 clinical trials
A Randomized, Placebo-controlled, Double-blind, Multicenter Study to Assess the Efficacy and Safety of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

The purpose of this study is to evaluate the efficacy and safety of nipocalimab in participants with primary Sjogren's syndrome (pSS) versus placebo.

rheumatism
  • 61 views
  • 14 Oct, 2022
  • 60 locations
  • 5 views
  • 25 Oct, 2022
  • 19 locations
Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis

Sjögren's Syndrome (pSS), or branebrutinib treatment followed by open-label abatacept treatment in study participants with active Rheumatoid Arthritis (RA).

progressive systemic sclerosis
sjogren's syndrome
abatacept
lupus
arthritis
  • 417 views
  • 04 Oct, 2022
  • 66 locations
Master Protocol to Assess Safety and Dose of First Time in Human Next Generation Engineered T Cells in NY-ESO-1 and/or LAGE-1a Positive Advanced Solid Tumors

This trial will evaluate the safety and efficacy of first time in human engineered T-cell therapies, in participants with advanced tumors.

sarcoma
treatment regimen
targeted therapy
ROS1
primary cancer
  • 0 views
  • 07 Oct, 2022
  • 19 locations
CEQUA for Sjogren's Syndrome Dry Eye

The primary objective of this study is to show that CEQUA (cyclosporine 0.09% ophthalmic solution) improves symptoms of dry eye disease in a population of patients with Sjogren's Syndrome

  • 3 views
  • 04 Oct, 2022
  • 1 location
Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments.

This study aims at elucidating the mechanism of action of ianalumab in salivary glands and explore relationships with clinical assessments

  • 0 views
  • 04 Oct, 2022
  • 1 location
ANIfrolumab Treatment for 24 Weeks in Patients With Primary Sjögren's Syndrome - Efficacy and Safety Assessment in a Randomized, Double-blind, Placebo-controlled Phase-IIa Proof-of-concept Trial (ANISE-II) (ANISE-II)

The ANISE-II study is a randomized, double-blind, placebo-controlled phase IIa proof-of-concept trial. Thirty patients with primary Sjögren's syndrome (pSS) are randomized in a 2:1 ratio to

  • 0 views
  • 17 Oct, 2022
  • 1 location
A Multi-center, Prospective, Open-label, Randomized Study to Explore Efficacy and Safety of Baricitinib in Active Primary Sjogren's Syndrome Patients

The investigators had observed that baricitinib was effective and safe in active pSS patients in a pilot study. So the investigators plan to conduct a multi-center, prospective, open-label, randomized study to compare the efficacy of baricitinib + hydroxychloroquine (HCQ) with HCQ alone in active pSS patients. The participants will be …

hydroxychloroquine
baricitinib
  • 0 views
  • 23 Oct, 2022
  • 1 location
Tivanisiran for Dry Eye in Subjects With Sjögren's Syndrome

of dry eye disease (DED) due to Sjögren's Syndrome.

  • 40 views
  • 18 Oct, 2022
  • 30 locations
Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sj(SqrRoot)(Delta)Gren's Syndrome; a Phase Ib-IIa Placebo-controlled Clinical Trial and Associated Mechanistic Studies

Background An autoimmune disease is one in which the immune system attacks a person s own body. Sjogren's syndrome (SS) is an autoimmune disease. It often involves

hydroxychloroquine
glucocorticoids
chloroquine
tofacitinib
autoimmune disease
  • 0 views
  • 22 Oct, 2022
  • 1 location