Sjogren's syndrome Clinical Trials

A listing of Sjogren's syndrome medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 28 clinical trials
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Safety, Tolerability, Pharmacokinetics, and Therapeutic Efficacy of SAR441344 in Primary Sjögren's Syndrome (pSjS)

Primary Objective: To evaluate the therapeutic efficacy of one dose level of SAR441344 versus placebo over 12 weeks in adult patients with primary Sjögren's syndrome (pSjS), assessed by

  • 0 views
  • 03 Dec, 2021
  • 30 locations
None
CAMPFIRE: A Study of Ramucirumab (LY3009806) in Children and Young Adults With Synovial Sarcoma

This study is being conducted to test the safety and efficacy of ramucirumab in combination with other chemotherapy in the treatment of relapsed, recurrent, or refractory synovial sarcoma (SS

  • 7 views
  • 05 Dec, 2021
  • 75 locations
None
Patient Decision Aid for Opioid Use Disorder

The aim of the study is to test the effectiveness of the Patient Decision Aid for Opioid Use Disorder (PtDA-MAT) by conducting a stepped-wedge cluster-randomized trial in CA H&SS (stratified

narcotic use
drug use
substance use
  • 50 views
  • 24 Nov, 2021
  • 1 location
None
Topical Infliximab for Sterile Corneal Melt

a sterile corneal melt (without an infection) caused by diseases such as rosacea, Sjogren's syndrome, rheumatoid arthritis, Crohn's disease, Stevens Johnson syndrome, as well as toxic epidermal

  • 8 views
  • 25 Nov, 2021
  • 2 locations
None
A Study of Nipocalimab in Adults With Primary Sjogren's Syndrome (pSS)

The purpose of this study is to evaluate the efficacy and safety of nipocalimab in participants with primary Sjogren's syndrome (pSS) versus placebo.

rheumatism
  • 7 views
  • 02 Dec, 2021
  • 40 locations
None
Safety Tolerability Pharmacokinetics and Therapeutic Efficacy of SAR441344 in Primary Sj gren's Syndrome (pSjS)

Primary Objective: To evaluate the therapeutic efficacy of one dose level of SAR441344 versus placebo over 12 weeks in adult patients with primary Sjgren's syndrome (pSjS), assessed by the change of the European League Against Rheumatism (EULAR) Sjgren's Syndrome Disease Activity Index (ESSDAI) Secondary Objectives: To evaluate the therapeutic efficacy …

  • 90 views
  • 02 Dec, 2021
  • 60 locations
None
Study of Safety and Efficacy of Multiple Doses of CFZ533 in Two Distinct Populations of Patients With Sj gren's Syndrome

This study will evaluate safety, efficacy, pharmacokinetics (PK) and pharmacodynamics (PD) of multiple doses of CFZ533 (iscalimab) in patients with Sjgren's Syndrome.

fatigue
  • 100 views
  • 05 Dec, 2021
  • 76 locations
None
Study of Safety and Tolerability of CFZ533 in Patients With Sj gren's Syndrome

This study will evaluate the safety and tolerability of iscalimab at two dose levels in patients with Sjgren's Syndrome, who participated in the TWINSS core study, CCFZ533B2201(NCT03905525). Additionally, this Extension study will further explore the pharmacokinetics (PK) and efficacy of iscalimab at two dose level.

  • 0 views
  • 05 Dec, 2021
  • 15 locations
None
A Phase 2 Study to Evaluate the Safety and Efficacy of LOU064 in Patients With Moderate to Severe Sj gren's Syndrome

LOU064 is an oral Bruton's tyrosine kinase (BTK) inhibitor. This study is an adaptive phase 2 study designed to establish safety and efficacy and characterize the dose-response of LOU064 in subjects with moderate to severe Sjgren's syndrome.

  • 159 views
  • 05 Dec, 2021
  • 28 locations
None
Phase III Trial of Anlotinib Catequentinib in Advanced Alveolar Soft Part Sarcoma Leiomyosarcoma Synovial Sarcoma (APROMISS)

sarcoma (SS). All participants with ASPS will receive open-label AL3818. In participants with LMS or SS, AL3818 will be compared to IV dacarbazine. Two-thirds of the participants will receive AL3818, one

cancer
angiogenesis
synovial sarcoma
renal function
systemic therapy
  • 325 views
  • 01 Dec, 2021
  • 24 locations