Sinusitis Clinical Trials

A listing of Sinusitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 50 clinical trials
Surveillance of Non-invasive Streptococcus Pneumoniae Infections in Belgium

The investigators will conduct a prospective observational study of non-invasive S. pneumoniae infections in Belgium and characterize serotype distributions to evaluate national vaccination programs.

vaccination
sinusitis
streptococcus pneumoniae infections
pneumonia
  • 0 views
  • 07 Oct, 2021
  • 1 location
Central Nervous System Disorders Following Hematopoietic Stem Cell Transplantation

All patients undergoing allogeneic or autologous HSCT at the participating centres will be observed. Once a diagnosis of CNS disorder is made, additional data will be reported for these patients. We will identify clinical and diagnostic characteristics such as cerebrospinal fluid (CSF) and neuroimaging patterns, risk factors, response to treatment …

colony stimulating factor
antifungal
cell transplantation
  • 0 views
  • 20 Jun, 2022
  • 17 locations
High Resolution Micro OCT Imaging

The purpose of this study is to learn about using the imaging to make images of the lungs and nose with the long-term goal of the research leading to potential treatments and new therapies for patients with cystic fibrosis.

fibrosis
Accepts healthy volunteers
respiratory disease
respiratory disorder
cystic fibrosis
  • 42 views
  • 22 Mar, 2022
  • 1 location
Eosinophils Endotypes in Chronic Airway Inflammatory Diseases (PLEIAD)

Asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) are frequently described as unified airway inflammatory diseases. Both heavily impacts quality of life with substantial productivity loss. They share the same pathophysiologic pattern based upon proTh2 immune response with blood eosinophils recruitment. Eosinophils are the major actor of persistent mucosal inflammation …

  • 0 views
  • 24 May, 2022
  • 1 location
Treatment With Mepolizumab on Patients With Severe Refractory Eosinophilic Asthma With or Without CRSwNP.

Patients with severe or difficult-to-treat asthma represent a small amount of total asthmatic patients, but weight on the national health system for the costs of disease management. Chronic rhinosinusitis with nasal polyposis, which the Italian severe/uncontrolled asthma registry reported with a prevalence of 30%, represents a comorbidity that significantly impact …

other disease
Accepts healthy volunteers
  • 0 views
  • 21 Mar, 2022
  • 1 location
Impact of Sinus Surgery on Individuals With Cystic Fibrosis

This study will be a prospective, observational study of patients who undergo endoscopic sinus surgery for cystic fibrosis-related chronic rhinosinusitis (CRS). Individuals who do not undergo surgery but are treated medically for CRS will also be enrolled to serve as a control group. Outcomes analyzed will include pulmonary, quality of …

fibrosis
rhinosinusitis
medical therapy
sinus surgery
sweat test
  • 16 views
  • 02 Jun, 2022
  • 1 location
Tissue Immune Interaction in Nasal Polyposis (TIP)

This is a cross-sectional study of up to 100 subjects who are undergoing clinically indicated sinus procedures to treat chronic rhinosinusitis. Participants will be asked to donate leftover sino-nasal secretions, sino-nasal tissue and blood as well as undergo partial characterization. As optional extensions of the main study, participants may also …

  • 0 views
  • 25 Mar, 2022
  • 1 location
Correlation Between the HRIM and VFSS

In many cases, the manometric examination is not feasible because of the pharyngeal sinusitis or pharyngeal torsion. In addition, although previous conventional manometry was used to estimate

  • 0 views
  • 26 Jan, 2021
  • 1 location
The Sinonasal Cavity as a Reservoir for Upper Airway Bacterial Development

While the maternal-newborn exchange of airway microbiota is well-documented, no studies have examined within-subject relationships among the mouth, sinuses, nasopharynx and lungs and the relative abundance of bacterial taxa at those sites. Recent evidence suggests the oral cavity may serve as a reservoir for pathogens that translocate to non-oral locations; …

sweat test
  • 67 views
  • 19 Apr, 2022
  • 1 location
CGRP Inhibition, Autonomic Function, and Migraine (CGRP-1)

The purpose of this clinical study is to better understand the function of the autonomic nervous system in patients with migraine. We aim to understand whether the autonomic functions change depending on the migraine status (i.e. whether they are between or during attacks) and whether the CGRP monoclonal antibody (mAb) …

Accepts healthy volunteers
  • 0 views
  • 24 Apr, 2022
  • 1 location