Sinusitis Clinical Trials

A listing of Sinusitis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 50 clinical trials
Endoscopic Sinus Surgery in Recurrent Acute Rhinosinusitis

The aim of this study is to find out if endoscopic sinus surgery improves the quality of life in patients suffering from recurrent acute rhinosinusitis. Our main outcome is the difference between the average change in disease-specific SNOT-22 quality of life questionnaire scores (from baseline to 5-6 months follow-up) between …

acute rhinosinusitis
sinusitis
rhinorrhea
antibiotics
congestion
  • 174 views
  • 25 Feb, 2022
  • 1 location
In-clinic Endoscopic Polypectomy for Chronic Sinusitis With Nasal Polyps

Chronic rhinosinusitis, also called chronic sinusitis, is a very common life-long disease affecting over 5% of the Canadian population. Its symptoms, including daily facial pain and headache, an

anosmia
nasal endoscopy
sinusitis
rhinoscopy
endoscopy
  • 1398 views
  • 02 May, 2022
  • 4 locations
Microbiota Transfer for Chronic Rhinosinusitis (SNMT)

Chronic sinusitis (CRS) is a common inflammatory condition of the sinuses that affects up to 2.5% of the Canadian population, and is thought to be caused by bacterial infection, resistant

chronic sinusitis
obstruction
facial pain
antibiotics
rhinosinusitis
  • 0 views
  • 27 Jul, 2022
  • 1 location
Efficacy and Safety of Modified Release Cefpodoxime Formulation in the Treatment of Acute Sinusitis.

The aim of this study is to compare the efficacy and safety of cefpodoxime 200 mg immediate (b.i.d) and cefpodoxime 400 mg modified release (q.d) tablet formulations in the treatment of acute bacterial rhinosinusitis.

acute rhinosinusitis
sinusitis
acute sinusitis
hyposmia
fever
  • 15 views
  • 18 Dec, 2021
  • 2 locations
Establishment of Precise Diagnosis and Treatment System for Refractory Chronic Rhinosinusitis

intrinsic markers were explored combined with follow-up results. The development of this project contributes to the establishment of a precise diagnosis and treatment system for refractory chronic sinusitis

mometasone
nasal polyps
sinusitis
asthma
omalizumab
  • 0 views
  • 03 Jun, 2022
  • 1 location
Dupilumab in CRSsNP (Liberty CRSsNP ORION)  

to reduce the incidence of participants with CRSsNP worsening/acute sinusitis who require treatment with antibiotics, systemic corticosteroids (SCS) or sinus surgery compared to placebo To

facial pain
sinusitis
antibiotics
rhinorrhea
congestion
  • 1 views
  • 25 Jul, 2022
  • 1 location
Pain Management Following Sinus Surgery

This Study evaluates the effect of adding Non-steroidal anti-inflammatories (NSAIDs) to the post-operative pain management of sinus surgery patients and wether or not this addition reduces or eliminates the need for narcotic pain medications. Patients will be instructed to take an NSAID regimen after surgery and will be instructed to …

narcotics
oxycodone
analgesia
anti-inflammatory agent
Accepts healthy volunteers
  • 63 views
  • 18 Feb, 2022
  • 1 location
Ivacaftor for Acquired CFTR Dysfunction in Chronic Rhinosinusitis

The purpose of this pilot study is to explore wither ivacaftor in refractory CRS patients will demonstrate safety and tolerability; restore CFTR-mediated Cl- secretions as measured by EDSPD testing; produce detectable improvements in validated measures of CRS including the SNOT-22 questionnaire, Lund-MacKay CT scan grading, and Lund-Kennedy endoscopic scores; and …

cavities
ivacaftor
ct scan
rhinosinusitis
  • 6 views
  • 15 Jul, 2022
  • 1 location
The Causal Relation of Nasal Nitric Oxide Levels to the Severity of Chronic Rhinosinusitis and Its Inflammatory Phenotype

the relation of chronic rhino sinusitis (CRS) severity and inflammatory status to nNO, maxillary sinus NO, nitrite, nitrate and cone beam computed tomography (CBCT). Three groups (22 patients

nitrite
rhinosinusitis
Accepts healthy volunteers
ct scan
asthma
  • 0 views
  • 21 Mar, 2022
  • 1 location
Functional Endoscopic Sinus Surgery Study (FESS)

The aim of this study is to evaluate the effect of the addition of epinephrine to bilateral real time ultrasound guided pterygopalatine ganglion blocks on intra-operative bleeding and blood loss during functional endoscopic sinus surgery (FESS).

sinus surgery
  • 0 views
  • 26 Jul, 2022
  • 1 location