Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 266 clinical trials
L-Glutamine Therapy for Sickle Cell Anemia

This is a study to determine the efficacy of L-glutamine as therapy for sickle cell anemia and sickle O-thalassemia.

thalassemia
glutamine
anemia
  • 86 views
  • 07 Nov, 2020
  • 1 location
Sleep and Pain in Sickle Cell Disease

This is a study testing the effects of behavioral sleep interventions on pain and brain function in sickle cell disease.

insomnia
sleep problem
chronic pain
thalassemia
hemoglobinopathy
  • 36 views
  • 26 Jan, 2022
  • 1 location
Desmopressin for Bedwetting in Children With SCD

This study assesses if using the medication desmopressin will decrease nightime bedwetting in children with sickle cell disease.

hemoglobin s
nocturnal enuresis
thal
desmopressin
  • 0 views
  • 26 Jan, 2022
  • 1 location
Study of Safety and Efficacy of Genome-edited Hematopoietic Stem and Progenitor Cells in Sickle Cell Disease (SCD)

fetal hemoglobin (HbF) and reducing complications of sickle cell disease.

priapism
thalassemia
stroke
sickle hemoglobin
hemoglobin c disease
  • 2 views
  • 26 Jan, 2022
  • 3 locations
A Study to Evaluate GBT021601-012 Single Dose and Multiple Dose in Participants With Sickle Cell Disease (SCD)

GBT021601, a hemoglobin S (HbS) polymerization inhibitor, in participants with SCD, following single and multiple ascending doses.

hemoglobin s
sickle hemoglobin
  • 0 views
  • 26 Jan, 2022
  • 1 location
Comparing Individualized vs. Weight Based Protocols to Treat VOE in SCD Occlusive Episodes in Sickle Cell Disease (COMPARE-VOE)

The purpose of this research study is to compare two different ways to give opioid pain medicine to treat sickle cell disease pain that is bad enough to go to the emergency department for

hemoglobin s
analgesics
thalassemia
morphine
opioid
  • 12 views
  • 26 Jan, 2022
  • 6 locations
Community Health Workers and mHealth for Sickle Cell Disease Care

-related quality of life and acute care use for transitioning youth with sickle cell disease (SCD), and identify and quantify mediators and moderators of intervention treatment effects.

thal
Accepts healthy volunteers
sickle hemoglobin
hemoglobin c disease
  • 0 views
  • 26 Jan, 2022
  • 5 locations
Stem Cell Transplant in Patients With Severe Sickle Cell Disease

This is a prospective pilot study of matched-related donor allogeneic stem cell transplantation in adults with severe sickle cell disease using a matched-sibling PBSC graft with a non

hemoglobin s
priapism
transplant conditioning
sickle cell trait
alemtuzumab
  • 30 views
  • 26 Jan, 2022
  • 1 location
Gene Transfer for Patients With Sickle Cell Disease

The purpose of this Phase 1/2 study is to determine the feasibility and safety of stem cell collection and gamma-globin gene transfer, and success of gene correction in subjects with sickle cell

melphalan
apheresis
analgesia
gene therapy
chest syndrome
  • 370 views
  • 26 Jan, 2022
  • 4 locations
Reduced Intensity Transplantation for Severe Sickle Cell Disease

children and young adults with Sickle Cell Disease (SCD). Patients less than or equal to 25 years old with SCD who would likely benefit from allogeneic hematopoietic cell transplantation (HCT) will be

cerebral blood flow
priapism
sickle cell trait
alemtuzumab
cell transplantation
  • 0 views
  • 26 Jan, 2022
  • 1 location