Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 265 clinical trials
Ph I/II Study of Allogeneic SCT for Clinically Aggressive Sickle Cell Disease (SCD)

immune- suppressive agents and low-dose total body irradiation (TBI) without standard chemotherapy in patients with aggressive sickle cell disease who are not candidates for or experienced complications

hydroxyurea
alloimmunization
sirolimus
hemoglobin s
carbon monoxide
  • 28 views
  • 19 Oct, 2021
  • 1 location
Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using Plerixafor

administration of plerixafor in pediatric and young adult patients with sickle cell disease (SCD). To estimate the number of CD34+ cells/kg of body weight that can be collected with peripheral

hydroxyurea
gene therapy
conjugated bilirubin
blood transfusion
plerixafor
  • 0 views
  • 06 Dec, 2021
  • 1 location
Fitness Trial in Adults With Sickle Cell Disease (SCD Fit): A Feasibility Study

The purpose of this project is to develop novel approaches to promote health and longevity while enhancing quality of life among persons with Sickle cell disease (SCD). Therefore, investigators

vaso-occlusive crisis
  • 0 views
  • 30 Sep, 2021
  • 1 location
T-Cell Depleted Alternative Donor Bone Marrow Transplant for Sickle Cell Disease (SCD) and Other Anemias

The purpose of this study is to evaluate what effect, if any, mismatched unrelated volunteer donor and/or haploidentical related donor stem cell transplant may have on severe sickle cell disease

iron
shortening fraction
bone marrow transplant
thalassemia
transcranial doppler ultrasonography
  • 46 views
  • 01 Nov, 2021
  • 2 locations
Selective Cytopheretic Device (SCD) Trial

awaiting LVAD implantation. In this study patients who are eligible and agree to participate will receive treatment with the SCD. The treatment will be for 6 hours a day up to 6 days. Additionally

diuretic therapy
medical therapy
valsartan
loop diuretic
inotropic agent
  • 0 views
  • 14 Aug, 2021
  • 1 location
Gene Transfer for Sickle Cell Disease

with sickle cell disease.

platelet count
bone marrow transplant
thalassemia
hemoglobin f
gene therapy
  • 203 views
  • 15 Dec, 2021
  • 2 locations
Sleep Apnea in Sickle Cell Disease

pathophysiological mechanisms are scarce. OSA is one of the most common conditions responsible for hemoglobin desaturation. The nocturnal hemoglobin desaturation occurring in some sickle cell disease (SCD) patients

blood transfusion
vaso-occlusive crisis
sickle cell trait
hemoglobin s
sickle hemoglobin
  • 10 views
  • 28 Jan, 2021
  • 5 locations
PINPOINT: Gaming Technology for SCD Pain

Sickle cell disease (SCD) is a common genetic disorder characterized by episodes of pain, yet programs to assist SCD adolescents with better identification and communication about pain are

genetic disorder
Accepts healthy volunteers
  • 0 views
  • 01 Dec, 2021
  • 2 locations
Imatinib for Pain in Sickle Cell Anemia

phosphorylation and the abundances of RBC-derived microparticles in their blood. In addition, the patients will be monitored for symptoms of sickle cell disease (SCD). The investigators expect band 3 tyrosine

opiates
electrophoresis
Accepts healthy volunteers
thalassemia
absolute neutrophil count
  • 0 views
  • 01 Dec, 2021
  • 2 locations
Health Literacy - Neurocognitive Screening in Pediatric SCD

appropriate format of neurocognitive evaluation feedback in the context of a routine screening program offered as a standard of care in the CHW pediatric sickle cell disease clinic. The specific aims is (1

  • 0 views
  • 01 Dec, 2021
  • 2 locations