Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

Filter By
Clear all Advanced
I am/have/had
added new label for I am/have/had
more
I am looking for
added new label for I am looking for
more
Advanced Filters
Found 216 clinical trials
L-Glutamine Therapy for Sickle Cell Anemia

This is a study to determine the efficacy of L-glutamine as therapy for sickle cell anemia and sickle O-thalassemia.

thalassemia
glutamine
anemia
  • 86 views
  • 07 Nov, 2020
  • 1 location
Sleep and Pain in Sickle Cell Disease

This is a study testing the effects of behavioral sleep interventions on pain and brain function in sickle cell disease.

thalassemia
hemoglobinopathy
insomnia
sleep problem
behavioral symptoms
  • 36 views
  • 26 Jan, 2022
  • 1 location
Community Health Workers and mHealth for Sickle Cell Disease Care

-related quality of life and acute care use for transitioning youth with sickle cell disease (SCD), and identify and quantify mediators and moderators of intervention treatment effects.

Accepts healthy volunteers
thal
hemoglobin c disease
sickle hemoglobin
  • 0 views
  • 26 Jan, 2022
  • 5 locations
Stem Cell Transplant in Patients With Severe Sickle Cell Disease

This is a prospective pilot study of matched-related donor allogeneic stem cell transplantation in adults with severe sickle cell disease using a matched-sibling PBSC graft with a non

hydroxyurea
transplant conditioning
blood transfusion
hemolysis
sirolimus
  • 30 views
  • 26 Jan, 2022
  • 1 location
Gene Transfer for Patients With Sickle Cell Disease

The purpose of this Phase 1/2 study is to determine the feasibility and safety of stem cell collection and gamma-globin gene transfer, and success of gene correction in subjects with sickle cell

hydroxyurea
plerixafor
melphalan
chest syndrome
analgesia
  • 370 views
  • 26 Jan, 2022
  • 4 locations
Reduced Intensity Transplantation for Severe Sickle Cell Disease

children and young adults with Sickle Cell Disease (SCD). Patients less than or equal to 25 years old with SCD who would likely benefit from allogeneic hematopoietic cell transplantation (HCT) will be

hemoglobinopathy
hydroxyurea
transcranial doppler ultrasonography
plerixafor
cyclophosphamide
  • 0 views
  • 26 Jan, 2022
  • 1 location
Hematopoietic Stem Cell Transplant for Sickle Cell Disease

This is a phase I/II study of patients with sickle cell disease. It aims to find out if people with sickle cell disease can be cured by changing their immune system before they have blood stem

direct bilirubin
hemoglobin c disease
anti-thymocyte globulin
conjugated bilirubin
blood transfusion
  • 84 views
  • 26 Jan, 2022
  • 1 location
Red Blood Cell Survival in Sickle Cell Disease

This is a single-arm, mechanistic clinical trial to measure predictors of senescence and the in vivo survival of transfused red blood cells (RBCs) in individuals with sickle cell disease (SCD

thalassemia
blood transfusion
sickle hemoglobin
  • 0 views
  • 26 Jan, 2022
  • 3 locations
Losartan for Diffuse Myocardial Fibrosis in Sickle Cell Disease

This study is a pilot, phase II, open-label study of the angiotensin II receptor blocker, losartan, in patients with Sickle Cell Disease (SCD) 6 years or older for 12 months. The investigators

Accepts healthy volunteers
  • 0 views
  • 26 Jan, 2022
  • 1 location
Folic Acid Supplementation in Children With Sickle Cell Disease

Folic acid supplementation (1mg/d) is the standard recommendation for Canadian children with Sickle cell disease (SCD), even though it can provide up to six times the recommended intake amount

  • 8 views
  • 26 Jan, 2022
  • 1 location