Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 216 clinical trials
LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study) (ST3P-UP)

This multi-center study will compare the effectiveness of adding virtual peer mentoring (PM) to a structured education-based (STE) transition program for emerging adults with sickle cell disease

  • 15 views
  • 26 Jan, 2022
  • 14 locations
Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Sickle Cell Anaemia

Sickle Cell Anaemia (SCA) is an inherited disease that makes the body produce red blood cells with abnormal sickle-shaped cells. The sickle-shaped cells are rigid, not flexible and break up

  • 0 views
  • 18 Aug, 2021
  • 3 locations
Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin (GRAY-ZONE)

The study evaluates the effect of platelet inhibition and / or lipid lowering in non-ACS-patients with symptoms suggestive for ACS, and elevated high-sensitivity troponin values

  • 6 views
  • 26 Jan, 2022
  • 6 locations
Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702) (BMT CTN 1702)

The purpose of this study is to determine if a search strategy of searching for an HLA-matched unrelated donor for allogeneic transplantation if possible then an alternative donor if an HLA-matched unrelated donor is not available versus proceeding directly to an alternative donor transplant will result in better survival for …

allogeneic transplantation
cell transplantation
transplant conditioning
graft versus host disease
biological factors
  • 90 views
  • 26 Jan, 2022
  • 50 locations
Outcomes Mandate National Integration With Cannabis as Medicine for Prevention and Treatment of COVID-19 (OMNI-Can)

This will be a multistate, multicenter clinical study to determine the efficacy and safety of medical cannabis for a wide variety of chronic medical conditions.

medical marijuana
covid-19
brimonidine tartrate ophthalmic solution
disease or disorder
Accepts healthy volunteers
  • 13108 views
  • 26 Jan, 2022
  • 16 locations
PROphylaxis for Venous ThromboEmbolism in Severe Traumatic Brain Injury (PROTEST)

This is a pilot study, phase III, multi-centre, double blind, randomized controlled trial of patients with traumatic brain injury (TBI).

subarachnoid hemorrhage
traumatic brain injury
severe traumatic brain injury
  • 104 views
  • 24 Jun, 2021
  • 10 locations
Safety of Single Doses of CSL889 in Adult Patients With Sickle Cell Disease Sickle Cell Disease

biomarkers of target engagement of CSL889 following single intravenous (IV) doses in subjects with sickle cell disease (SCD). The study involves sequential dose escalation of cohorts with between-group

hydroxyurea
glutamine
thalassemia
  • 0 views
  • 26 Jan, 2022
  • 7 locations
Imatinib for Pain in Sickle Cell Anemia (IMPACT)

phosphorylation and the abundances of RBC-derived microparticles in their blood. In addition, the patients will be monitored for symptoms of sickle cell disease (SCD). The investigators expect band 3 tyrosine

opiates
electrophoresis
opioid
Accepts healthy volunteers
absolute neutrophil count
  • 0 views
  • 26 Jan, 2022
  • 2 locations
Gene Transfer for Sickle Cell Disease

with sickle cell disease.

priapism
opioid
gene therapy
genetic disorder
bone marrow transplant
  • 203 views
  • 26 Jan, 2022
  • 2 locations
Sleep Apnea in Sickle Cell Disease (DREPAPNEE)

pathophysiological mechanisms are scarce. OSA is one of the most common conditions responsible for hemoglobin desaturation. The nocturnal hemoglobin desaturation occurring in some sickle cell disease (SCD) patients

hemoglobin s
sickle hemoglobin
vaso-occlusive crisis
blood transfusion
sickle cell trait
  • 10 views
  • 26 Jan, 2022
  • 3 locations