Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 228 clinical trials
Links Between Cognitive Functions and Clinical, Biological and Neuroradiological Outcomes in Adults With Sickle Cell Disease. (Drépa-COG)

Sickle cell disease (SCD) is an inherited blood disorder. Symptoms include acute and chronic complications. Due to progress in SCD care, patients with SCD are living longer than before and we

transcranial doppler ultrasonography
acute chest syndrome
vaso-occlusive crisis
blood disorder
chest syndrome
  • 0 views
  • 06 Apr, 2022
  • 1 location
Study of Erythrocyte Parameters and Hypercoagulability in Sickle Cell Disease (SCD-TGA) (SCD-TGA)

Sickle cell disease (SCD) is an inherited haemoglobinopathy disorder caused by mutations in HBB gene with amino-acid substitution on β globin chain. The consequence is synthesis of altered

Accepts healthy volunteers
  • 0 views
  • 27 May, 2022
  • 1 location
Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait

to and block a blood vessel in the lung (pulmonary embolism). Some people with sickle cell disease (SCD)-a red blood cell disorder-seem to be at greater risk for developing these blood clots

coagulopathy
sickle cell trait
thromboembolism
thrombosis
blood clot
  • 104 views
  • 25 May, 2022
  • 1 location
Improving Scientific Rigor of Renal Clinical Endpoints for Sickle Cell Anemia

The investigators will attempt to develop a more accurate equation to estimate eGFR in pediatric and adult sickle cell patients

Accepts healthy volunteers
thalassemia
anemia
  • 0 views
  • 18 Apr, 2022
  • 4 locations
Vitamin D Status in Children With Sickle Cell Disease Living in Lyon, France (EVADDREP)

Vitamin D deficiency may be under-diagnosed in sickle cell disease French children. Therefore, the investigator need an epidemiologic study about the prevalence of vitamin D deficiency in this

calcium
  • 0 views
  • 24 Mar, 2022
Cerebrovascular Reserve and White Matter Disease in Patients With Chronic Anemia (CVR)

This is primarily an observational trial in patients with chronic anemia syndromes (sickle cell disease and thalassemia) and control subjects. The key purpose is to understand how brain blood

blood transfusion
transfusion dependent thalassemia
acetazolamide
thalassemia
hydroxyurea
  • 17 views
  • 15 Feb, 2022
  • 1 location
Sickle Cell Hemoglobinopathies and Bone Health

try to understand why individuals with sickle cell disease (SCD) have thinner bones than healthy individuals do. Doctors have already discovered that people with sickle cell disease have very thin

electrophoresis
sickle cell trait
Accepts healthy volunteers
hemoglobin s
hemoglobinopathy
  • 60 views
  • 26 Jan, 2022
  • 1 location
Red Blood Cell - IMProving trAnsfusions for Chronically Transfused Recipients (RBC-IMPACT)

Red Blood Cell - IMProving trAnsfusions for Chronically Transfused recipients (RBC-IMPACT) is an observational cohort study to assess donor, component, and recipient factors that contribute to RBC efficacy in chronically and episodically transfused patients. The objective of the study is to determine how specific genetic and non-genetic factors in donors …

thalassemia
anemia
  • 0 views
  • 06 Apr, 2022
  • 1 location
Collection of Human Biospecimens for Basic and Clinical Research Into Globin Variants

Background Blood disorders like sickle cell disease and malaria affect many people around the world. Researchers want to learn more about blood disorders. To do

alpha globin
blood disorder
Accepts healthy volunteers
malaria
anemia
  • 81 views
  • 24 May, 2022
  • 1 location
Validating Pain Scales in Children and Young Adults

that can lead to cancer. Objectives To study the effectiveness of pain rating scales given to children and adults with Sickle Cell Disease (SCD

malignant solid tumor
cancer
sarcoma
solid tumor
  • 33 views
  • 24 May, 2022
  • 1 location