Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 265 clinical trials
Intravenous Gammaglobulin for Sickle Cell Pain Crises

The purpose of this study is to determine whether intravenous immune globulin is safe and effective in the acute treatment of pain crises in sickle cell disease.

  • 41 views
  • 07 Nov, 2020
  • 1 location
A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism

The goal of the study is to evaluate the efficacy and safety of crizanlizumab in SCD patients with priapism.

  • 24 views
  • 25 Nov, 2021
  • 20 locations
To Assess the Effect of SCD-044 Treatment on Moderate to Severe Plaque Psoriasis

This is a multicenter, randomized, double-blind, placebo-controlled study in subjects with moderate to severe plaque psoriasis.

  • 0 views
  • 10 May, 2021
  • 1 location
Hydroxyurea Therapy for Neurological and Cognitive Protection in Pediatric Sickle Cell Anemia in Uganda ( BRAINSAFE-II )

Worldwide, an estimated 200,000 babies are born with Sickle Cell Anemia (SCA) annually. Affected children suffer chronic ill health with some having frequent hospitalization. The patients are

  • 2 views
  • 12 Sep, 2021
  • 1 location
To Assess the Efficacy and Safety of SCD-044 in the Treatment of Moderate to Severe Atopic Dermatitis

This is a Phase II, randomized, double-blind, placebo-controlled study in subjects with moderate to severe atopic dermatitis.

  • 1 views
  • 12 Sep, 2021
  • 1 location
RH Genotype Matched RBC Transfusions

To determine the feasibility of matching donor red cells by RH genotype for a cohort of chronically transfused patients with SCD.

  • 1 views
  • 19 Oct, 2021
  • 1 location
Clinical and Biological Effects of Citrus-phytochemicals in Subjective Cognitive Decline.

Subjective cognitive decline (SCD) is receiving increasing attention as a risk factor for incident dementia due to AD. SCD manifests prior to the onset of clinical impairment, and as such could

  • 0 views
  • 10 May, 2021
  • 1 location
Impact of a Cognitive Intervention Enriched With Leisure Activities in Persons With Subjective Cognitive Decline

activities. This will be done with a partially randomized controlled double-blind preference trial with a comprehensive cohort design, in participants with subjective cognitive decline (SCD) recruited in

  • 28 views
  • 05 Feb, 2021
  • 2 locations
Senicapoc and Dehydrated Stomatocytosis

(KCNN4) channel or the mechanosensitive channel PIEZO1. Senicapoc is a selective blocker of the Gardos channel that has been extensively studied in sickle cell disease and shown to be safe with limited

  • 0 views
  • 13 Jun, 2021
  • 1 location
Sickle Cell Disease Hemechip

Sickle cell disease is very common in Nigeria. Early diagnosis is important to prevent or reduce serious complications from the disease and to enable children stay healthy. To this end, the

electrophoresis
Accepts healthy volunteers
  • 22 views
  • 19 Oct, 2021
  • 7 locations