Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 56 clinical trials
TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

disorders such as sickle cell disease. Currently, there are large and important gaps in the investigator's knowledge regarding incidence, etiology and optimal treatment of pulmonary complications. Moreover

stem cell transplantation
spirometry
  • 0 views
  • 24 May, 2022
  • 3 locations
Screening for Alpha Thalassemia in Healthy Volunteers

develop new treatments for blood diseases such as sickle cell disease. Objective To better understand how alpha globin deletions in healthy people affect blood vessels

decitabine
direct bilirubin
cancer
alpha-thalassemia
anemia
  • 78 views
  • 28 Jun, 2022
  • 1 location
STUDY INCIDENCE AND CHARACTERISTICS OF MALIGNANT NEOPLASIES IN PATIENTS WITH HEMOGLOBINOPATHY FOLLOWED IN ITALY (Tum001)

The Trial aims to increase the information available on the relevance of tumor pathology in hemoglobinopathies, updating the data relating to hepatocarcinoma and investigating which other tumors are more frequent in patients with hemoglobinopathies. Still, in relation to tumor pathology, the study will evaluate any differences between the different types …

  • 0 views
  • 26 Apr, 2022
  • 1 location
Stem Cell Collection for Adult Volunteers

This study will examine the development of stem cells (very immature cells produced by the bone marrow) and their potential to change into cells of other organ types. These cells will be studied for their potential use in creating replacement tissue for diseases ranging from diabetes to Parkinson s. Healthy …

Accepts healthy volunteers
  • 88 views
  • 14 Jun, 2022
  • 1 location
Venous Thromboembolism in Hematologic Malignancy and Hematopoietic Cell Transplant Patients: a Retrospective Study

Venous thromboembolism (VTE) is the second leading cause of death in patients with cancer, after disease progression. VTE is increasingly recognized as a complication in patients with hematologic malignancies and various studies have reported high rates of VTE. Critically ill patients are at high risk of VTE and should all …

clot
embolism
thromboembolism
cancer
venous thromboembolism
  • 0 views
  • 14 Jun, 2022
  • 1 location
Collection and Distribution of Blood Components From Healthy Donors for In Vitro Research Use

This protocol is designed to provide a mechanism for the Department of Transfusion Medicine, Clinical Center to collect and process blood components from paid, healthy volunteer donors for distribution to NIH intramural investigators and FDA researchers for in vitro laboratory use. Donors meeting research donor eligibility criteria will be recruited …

Accepts healthy volunteers
  • 16 views
  • 15 Jun, 2022
  • 1 location
Blood Sampling for Research Related to Sickle Cell Disease

This study will collect representative blood samples from healthy children and adults and from children and adults who have unique red blood cell features that are related to sickle cell disease

Accepts healthy volunteers
blood disorder
hemoglobin s
sickle hemoglobin
sickle cell trait
  • 5 views
  • 19 Jun, 2022
  • 1 location
Dietary Intake and Dietary Behaviors in Adults With Sickle Cell Disease

Background Sickle Cell Disease (SCD) causes blood cells form a crescent shape. It is caused by a genetic mutation in the hemoglobin gene. People with SCD are at

hemoglobinopathy
stroke
chronic pain
  • 0 views
  • 19 Jun, 2022
  • 1 location
A Study to Evaluate an Electronic Patient Diary in Adult Participants With Sickle Cell Disease

A study to learn the differences in health condition as self-reported by adult participants with Sickle Cell Disease (SCD) who are not on SCD-modifying therapy medicine versus participants that

exchange transfusion
glutamine
hydroxyurea
thalassemia
voxelotor
  • 0 views
  • 15 Jun, 2022
  • 1 location
Venous Thrombosis Biomarkers in Sickle Cell Disease and Sickle Cell Trait

to and block a blood vessel in the lung (pulmonary embolism). Some people with sickle cell disease (SCD)-a red blood cell disorder-seem to be at greater risk for developing these blood clots

thrombosis
thromboembolism
thalassemia
deep vein thrombosis
sickle cell trait
  • 104 views
  • 15 Jun, 2022
  • 1 location