Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 67 clinical trials
Featured trial
Sickle Cell Disease Research Study - Fulcrum Therapeutics  

The purpose of this study is to determine the safety and clinical effects of SCD-101 when given to adults with sickle cell disease.

  • 0 views
  • 02 Dec, 2021
  • 1 location
None
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

  • 44 views
  • 30 Nov, 2021
  • 293 locations
None
A Study to Evaluate the Safety and Efficacy of Crizanlizumab in Sickle Cell Disease Related Priapism

The goal of the study is to evaluate the efficacy and safety of crizanlizumab in SCD patients with priapism.

  • 24 views
  • 25 Nov, 2021
  • 20 locations
None
Study to Assess Efficacy and Safety of VIT-2763 in Subjects With Sickle Cell Disease

The purpose of this study is to investigate the efficacy, safety and tolerability of VIT-2763 for the treatment of sickle cell disease. It is a randomised, double-blind, placebo-controlled

hydroxyurea
sickle hemoglobin
  • 0 views
  • 01 Dec, 2021
  • 8 locations
None
Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

This is a multi-center multi-national rollover study to allow continued access to crizanlizumab for patients with sickle cell disease (SCD) who are on crizanlizumab treatment in a Novartis

  • 0 views
  • 05 Dec, 2021
  • 4 locations
None
Study of Two Doses of Crizanlizumab Versus Placebo in Adolescent and Adult Sickle Cell Disease Patients

The purpose of this study is to compare the efficacy and safety of 2 doses of crizanlizumab (5.0 mg/kg and 7.5 mg/kg) versus placebo in adolescent and adult sickle cell disease (SCD) patients

acute chest syndrome
vaso-occlusive crisis
opioid
conjugated bilirubin
splenic sequestration
  • 101 views
  • 24 Nov, 2021
  • 90 locations
None
LCI-HEM-SCD-ST3P-UP-001: The Sickle Cell Trevor Thompson Transition Project (ST3P-UP Study)

This multi-center study will compare the effectiveness of adding virtual peer mentoring (PM) to a structured education-based (STE) transition program for emerging adults with sickle cell disease

  • 15 views
  • 29 Nov, 2021
  • 14 locations
None
Clinical Transplant-Related Long-term Outcomes of Alternative Donor Allogeneic Transplantation (BMT CTN 1702)

The purpose of this study is to determine if a search strategy of searching for an HLA-matched unrelated donor for allogeneic transplantation if possible then an alternative donor if an HLA-matched unrelated donor is not available versus proceeding directly to an alternative donor transplant will result in better survival for …

graft versus host disease
biological factors
cell transplantation
allogeneic transplantation
transplant conditioning
  • 90 views
  • 05 Dec, 2021
  • 49 locations
None
Peripheral Blood Stem Cell Collection From Patients With Sickle Cell Disease (SCD) Using Plerixafor

administration of plerixafor in pediatric and young adult patients with sickle cell disease (SCD). To estimate the number of CD34+ cells/kg of body weight that can be collected with peripheral

plerixafor
blood transfusion
gene therapy
hydroxyurea
apheresis
  • 0 views
  • 05 Dec, 2021
  • 1 location
None
PINPOINT: Gaming Technology for SCD Pain

Sickle cell disease (SCD) is a common genetic disorder characterized by episodes of pain, yet programs to assist SCD adolescents with better identification and communication about pain are

genetic disorder
Accepts healthy volunteers
  • 0 views
  • 01 Dec, 2021
  • 2 locations