Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 276 clinical trials
Featured trial
Sickle Cell Disease Study

Study of Oral medication in Patients with Sickle Cell Disease.

sickle cell disease
  • 0 views
  • 26 Jan, 2021
  • 1 location
Featured trial
Sickle Cell Disease Research Study - Fulcrum Therapeutics  

The purpose of this study is to determine the safety and clinical effects of SCD-101 when given to adults with sickle cell disease.

  • 0 views
  • 02 Dec, 2021
  • 1 location
Featured trial
Sickle Cell Food Study

An Open Label Food Study to Assess the Safety, Tolerability and Physiological Effects of an Amino Acid Food Product in Subjects with Sickle Cell Disease  

  • 32 views
  • 25 Jan, 2021
  • 1 location
Featured trial
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the

stroke
red blood cell disorder
sickle cell disease
cell transplantation
  • 57 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Sickle Cell Single/Multiple Dose Study

A randomized, placebo-controlled, double blind, single ascending and multiple ascending dose study to assess the safety in healthy volunteers and sickle cell disease. Facility is in Miami, Florida

  • 9 views
  • 25 Jan, 2021
  • 1 location
Featured trial
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

sickle cell disease (SCD) symptoms. The PKLR gene helps create a protein, called pyruvate kinase that is essential in normal functioning of the red blood cell. Differences in the PKLR gene, called genetic

red blood cell disorder
sickle cell disease
sickle cell anemia
  • 50 views
  • 22 Dec, 2020
  • 1 location
Featured trial
H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.

H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.

  • 888 views
  • 08 Nov, 2020
  • 1 location
None
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD)

MI. Following a MI patients are at high risk of sudden cardiac death (SCD). The risk is highest in the first 40 days; however, current guidelines exclude patients from receiving an ICD during

  • 123 views
  • 18 Oct, 2021
  • 37 locations
None
Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

  • 32 views
  • 30 Nov, 2021
  • 293 locations
None
Prevention Of Morbidity In Sickle Cell Disease Pilot Phase

The hypothesis is that in sickle cell anaemia, nocturnal oxyhaemoglobin desaturation, is associated with low processing speed index, and this morbidity can be reduced with overnight auto

anemia
  • 24 views
  • 07 Nov, 2020
  • 1 location