Sickle Cell Disease Clinical Trials

A listing of Sickle Cell Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 294 clinical trials
Featured trial
 
  • 133 views
  • 06 Sep, 2022
  • 1 location
  • Online study
Featured trial
Sickle Cell Disease Research Study - Fulcrum Therapeutics  

The purpose of this study is to determine the safety and clinical effects of SCD-101 when given to adults with sickle cell disease.

hemoglobin f
thalassemia
  • 12948 views
  • 14 Sep, 2022
  • 5 locations
Featured trial
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease

Background: Peripheral blood stem cell transplantation procedures are used for people with sickle cell disease. Researchers want to improve the success and reduce the

stroke
sickle cell disease
cell transplantation
red blood cell disorder
  • 83 views
  • 22 Dec, 2020
  • 1 location
Featured trial
A Study of FT-4202 in Adults and Adolescents With Sickle Cell Disease (Hibiscus Study)

This clinical trial is a Phase 2/3 study that will evaluate the efficacy and safety of FT-4202 and test how well FT-4202 works compared to placebo to improve the amount of hemoglobin in the blood and to reduce the number of vaso-occlusive crises (times when the blood vessels become blocked …

hydroxyurea
  • 13 views
  • 22 Dec, 2021
  • 29 locations
Featured trial
Genotype -Phenotype Correlation of PKLR Variants with Pyruvate Kinase, 2,3-Diphosphglycerate and ATP Activities in Red Blood Cells of Patients with Sickle Cell Disease

sickle cell disease (SCD) symptoms. The PKLR gene helps create a protein, called pyruvate kinase that is essential in normal functioning of the red blood cell. Differences in the PKLR gene, called genetic

sickle cell disease
sickle cell anemia
red blood cell disorder
  • 63 views
  • 22 Dec, 2020
  • 1 location
Featured trial
Sickle Cell Single/Multiple Dose Study

A randomized, placebo-controlled, double blind, single ascending and multiple ascending dose study to assess the safety in healthy volunteers and sickle cell disease. Facility is in Miami, Florida

  • 9 views
  • 25 Jan, 2021
  • 1 location
Featured trial
H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.

H7T-MC-TADO(b): A Phase 3, Double-Blind, Randomized, Efficacy and Safety Comparison of Prasugrel and Placebo in Pediatric Patients With Sickle Cell Disease.

  • 910 views
  • 08 Nov, 2020
  • 1 location
Programmed Ventricular Stimulation to Risk Stratify for Early Cardioverter-Defibrillator (ICD) Implantation to Prevent Tachyarrhythmias Following Acute Myocardial Infarction (PROTECT-ICD) (PROTECT-ICD)

MI. Following a MI patients are at high risk of sudden cardiac death (SCD). The risk is highest in the first 40 days; however, current guidelines exclude patients from receiving an ICD during

  • 267 views
  • 15 May, 2022
  • 26 locations
An International, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Effect of Sodium Zirconium Cyclosilicate on Arrythmia-related Cardiovascular Outcomes in Participants on Chronic Hemodialysis With Recurrent Hyperkalemia (DIALIZE-Outcomes)

The purpose of this study is to evaluate the effect of Sodium Zirconium Cyclosilicate (SZC) on arrhythmia-related cardiovascular outcomes in participants on chronic hemodialysis with recurrent hyperkalemia.

  • 94 views
  • 23 Sep, 2022
  • 205 locations
The Effect of Voxelotor on Cerebral Hemodynamic Response in Children With Sickle Cell Anemia (VoxSCAN)

Voxelotor is a new drug for adolescents and adults with sickle cell disease that improves hemoglobin levels and reduces the incidence of worsening anemia. However, it is unclear whether this

  • 0 views
  • 19 Sep, 2022
  • 2 locations