Pompe Disease Clinical Trials

A listing of Pompe Disease medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 122 clinical trials
Visual Telerehabilitation in AMD Patients

of the retina (PRL), to compensate for visual impairments. However, in many cases, the PRL lands on a sub-optimal retinal area and becomes useless. Modern low-vision rehabilitation procedures for AMD

  • 0 views
  • 08 Oct, 2021
Study to Evaluate Efficacy and Safety in Chinese Patients With Late Onset Pompe Disease With Alglucosidase Alfa Treatmen

)] among Chinese Late Onset Pompe Disease patients above 5 years old. To evaluate the safety of Myozyme 20mg/kg, IV biweekly in Chinese LOPD patients above 3 years old. Secondary Objective

  • 0 views
  • 25 Mar, 2021
  • 1 location
Study to Evaluate Efficacy and Safety in Chinese Patients With Late Onset Pompe Disease With Alglucosidase Alfa Treatmen (APOLLO-LOPD)

)] among Chinese Late Onset Pompe Disease patients above 5 years old. To evaluate the safety of Myozyme 20mg/kg, IV biweekly in Chinese LOPD patients above 3 years old. Secondary Objective

deficiency
gaa gene
myozyme
alglucosidase alfa
beta-human chorionic gonadotropin
  • 0 views
  • 22 Jan, 2022
  • 1 location
MMP-9 Inhibition for Recalcitrant Wet AMD

Wet (or neovascular) form of age-related macular degeneration (wAMD) is the most common cause of blindness in the Western world. Currently, anti-vascular endothelial growth factor (VEGF) intravitreal injections (IVI) remain the standard-of-care treatment for wAMD. Previous studies show that about 90% of treated patients lose minimal visual function after 2 …

  • 0 views
  • 19 Feb, 2021
  • 1 location
CLN-0046: Treatment of AMD Subjects With OTX-TKI

To evaluate the safety, tolerability and efficacy of OTX-TKI for intravitreal use, in subjects who have neovascular age-related macular degeneration (AMD).

bevacizumab
anti-vegf therapy
vascular endothelial growth factor
vegf
spectral domain optical coherence tomography
  • 265 views
  • 29 Sep, 2021
  • 9 locations
Episcleral Brachytherapy for the Treatment of Wet AMD

This is a prospective, multi-site, safety and feasibility study of the SalutarisMD SMD-DA system for retrobulbar minimally invasive episcleral brachytherapy device in patients receiving and not responding to anti-VEGF therapy for nAMD. The trial will be open label and non-randomized. The study intervention is a one-time intervention and requires no …

  • 64 views
  • 04 Apr, 2021
  • 2 locations
PRIMA US-Feasibility Study in Atrophic Dry AMD

In this early feasibility trial the safety and performance of the new retinal prothesis PRIMA is tested in five subjects suffering from atrophic dry age related macular degeneration.

  • 127 views
  • 05 Feb, 2021
  • 2 locations
Vitamin A Palmitate Supplementation in People With Age-Related Macular Degeneration (and Without Reticular Pseudodrusen) and Delayed Dark Adaptation

Background Age-related macular degeneration (AMD) is an eye disease. It is the leading cause of vision loss in people over 55 in the U.S. Changes in the eye can

retinal diseases
macular degeneration
hysterectomy
reticular pseudodrusen
be 50
  • 111 views
  • 19 Jan, 2022
  • 1 location
Pivotal 1 Study of RGX-314 Gene Therapy in Participants With nAMD

RGX-314 is being developed as a novel one-time gene therapy for the treatment of neovascular (wet) age-related macular degeneration (wet AMD). Wet AMD is characterized by loss of vision due to

macular degeneration
retinal diseases
ranibizumab
lucentis
gene therapy
  • 1 views
  • 26 Sep, 2021
  • 26 locations
Retinal Imaging Using NOTAL-OCT V3.0

The study will include up to 250 AMD patients and up to 30 DR patients. In Tel Aviv medical center up to 100 AMD/ 20 DR patients will be recruited; In Assuta HaShalom up to 100 AMD/10 DR

edema
  • 4 views
  • 07 Dec, 2021
  • 2 locations