Pneumonia Clinical Trials

A listing of Pneumonia medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 85 clinical trials
Trial of Therapeutic Hypothermia in Patients With ARDS

. COVID-19 is considered an ARDS risk-factor and patients with ARDS secondary to COVID-19 pneumonia will be eligible for enrollment. Primary outcome is 28-day ventilator-free days. Secondary outcomes

bilateral pulmonary infiltrates
acute respiratory distress
  • 16 Jan, 2022
  • 11 locations
Feasibility and Accuracy of an Ultrasound Algorithm for Acute Dyspnea Diagnosis in the Emergency Department

>Inadequate treatment of chronic bronchitis decompensation is associated with a doubling of intra-hospital mortality. An initiation of antibiotic treatment within 4 hours of admission for pneumonia

  • 02 Jan, 2022
  • 8 locations
Utilization of Negative Pressure Suction to Reduce Aspiration in Oropharyngeal Dysphagia

This is an investigator initiated prospective study to determine whether the use of a negative pressure suction in the hypopharynx will reduce the amount of aspiration during Video Fluoroscopic Swallowing Exam (VFSE) among patients with oropharyngeal dysphagia.

  • 19 Jan, 2022
  • 1 location
Use of High Dose Radiation Followed by Chemotherapy and Radiation to Treat Locally Advanced NSCLC

This is a single-arm, single-stage Phase II study designed to evaluate the 1-year PFS rate in subjects with locally-advanced NSCLC (stage II/III) and treated with Stereotactic Body Radiation Therapy (SBRT) followed by concurrent mediastinal chemoradiation with or without consolidation chemotherapy. A total of 60 subjects will be enrolled to this …

total bilirubin
absolute neutrophil count
  • 02 Jan, 2022
  • 2 locations
Combination of Pembrolizumab With TGR-1202 in Patients With Relapsed/Refractory CLL and B-cell NHL

This study will be a standard 3+3 design with a lead in of TGR-1202 at dose of 600mg (dose level 1) or 800mg daily (dose level 2) for 6 weeks, i.e. 2 cycles, followed by pembrolizumab at 200mg every 3 weeks for 8 cycles along with TGR-1202 for patients with …

neutrophil count
measurable disease
direct bilirubin
chronic lymphocytic leukemia refractory
  • 16 Jan, 2022
  • 3 locations
Comprehensive Swallowing Rehabilitation in Patients With MSA

The purpose of this study is to investigate the effect of comprehensive swallowing rehabilitation in patients with multiple system atrophy.

  • 25 Jan, 2022
  • 1 location
Predictive Immune Biomarkers for COVID-19 Pathogenesis

The spectrum of the COVID-19 disease ranges from benign to asymptomatic to viral pneumopathy that can progress to acute respiratory distress syndrome (ARDS). The host-pathogen relationships and the physiopathological mechanisms underlying the clinical aggravation of COVID-19 patients remain misunderstood. The project aim is to create a prospective cohort of biological …

PCR test
acute respiratory distress
respiratory distress
  • 16 Jan, 2022
  • 1 location
To Identify Persons Who Are Susceptible to WSP-induced Inflammation and Examine the Role of GSTM1 and Other Factors in This Susceptibility

Purpose: This screening protocol is designed to assess PMN (neutrophil) responsiveness to wood smoke particles (WSP) and the effect of the GSTM1 null genotype on this response. The researches will identify persons responsive and resistant to the inflammatory effect of WSP. It is anticipated that the GSTM1 genotype will be …

Accepts healthy volunteers
  • 13 Jan, 2022
  • 1 location
Intratumor Injection of Anti-Mesothelin Immunotoxin LMB-100 With Ipilimumab in Malignant Mesothelioma

Background Mesothelioma is a type of cancer. It originates in cells that line human body cavities. Most people have advanced disease when they are diagnosed. Researchers want to see if a combination of drugs can help. Objective To find a safe dose of LMB-100 in combination with ipilimumab when LMB-100 …

neutrophil count
formalin-fixed paraffin-embedded
peritoneal mesothelioma
  • 07 Jan, 2022
  • 1 location
High Dose Peripheral Blood Stem Cell Transplantation With Post Transplant Cyclophosphamide for Patients With Chronic Granulomatous Disease

Chronic granulomatous disease (CGD) affects white blood cell function. Currently, the only curative treatment is bone marrow transplant to replace the abnormal stem cells with new ones (donor cells) capable of making a normal immune system. Transplant problems include graft versus host disease (GvHD) and graft rejection. With GvHD, donor …

  • 19 Jan, 2022
  • 1 location