Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 635 clinical trials
Magnesium Sulfate Versus Dexmedetomidine on Anesthesia Awakening.

Magnesium sulfate (MS) and dexmedetomidine have already demonstrated the ability to reduce intra and postoperative consumption of anesthetics and analgesics, among others advantages, such as

Accepts healthy volunteers
  • 11 Nov, 2021
  • 1 location
Hair Cortisol and Cushing's Disease

results of the measurement of cortisol and cortisone using high-performance liquid chromatography-tandem mass spectrometry (LC-MS/MS) in scalp hair (so called "Hair Cortisol") to that of 24h urinary free

urinary free cortisol
bilateral adrenalectomy
  • 22 Dec, 2021
  • 11 locations
AIH for Spinal Cord Repair

, cSCI. Because deficits in upper limb function are a major problem after stroke, amyotrophic lateral sclerosis, multiple sclerosis, and other motor disorders, this work may also be relevant for patients

  • 12 Apr, 2021
  • 1 location
Surgical Implantation of TRAnscatheter vaLve in Native Mitral Annular Calcification (SITRAL) Study

The purpose of this study is to establish the safety and feasibility of the Edwards SAPIEN 3 valve in subjects with mitral annular calcification (MAC) associated with mitral stenosis (MS) and/or

  • 02 Feb, 2021
  • 7 locations
Micropulsed Laser Trabeculoplasty Using Different Parameters

, Group two with 1000 mW. The other settings (300 micron of diameter, 300 ms of duration, 15% duty cycle) are the same for both groups, and the laser is applied for 360. The main outcome is to

primary open angle glaucoma
intraocular pressure
laser trabeculoplasty
brimonidine tartrate ophthalmic solution
  • 30 May, 2021
  • 1 location
Surgical Weight Loss and Alcohol Perception

pilot data on the effects of metabolic surgery (MS), also known as bariatric surgery, on the metabolism of alcohol. These data will be used as preliminary evidence in support of a subsequent application

bypass surgery
gastric bypass
Accepts healthy volunteers
  • 18 Nov, 2021
  • 1 location
Parker Flex-it Stylet Versus Malleable Stylet in Orotracheal Intubation Using a Fiber-optic Laryngoscope

clinical trial; carried out on 60 patients requiring OTI under general anesthesia at our hospital. Patients were randomly allocated into two equal groups; group DS, intubated using PFDS, and group MS

  • 19 Jan, 2022
  • 1 location
Assessment of Clemastine Fumarate as a Remyelinating Agent in Acute Optic Neuritis (ReCOVER)

The main purpose of this study is to assess clemastine as a remyelinating agent in patients with acute optic neuritis.The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with optic neuritis. Study procedures will include assessments for evidence of remyelination in the anterior …

  • 14 Nov, 2021
  • 1 location
Naproxen Pharmacogenetic Study (Project 1 Aim 2)

This is a mechanism-based study in healthy adults to determine the effect of the CYP2C9 M1L gene polymorphism on the functional activity of the encoded CYP2C9 enzyme towards the probe substrate naproxen. CYP2C9 activity will be evaluated by measurement of O-desmethyl naproxen and unchanged naproxen in 24-hour urine following administration …

  • 24 Jan, 2021
  • 1 location
Vitamin K Supplementation Study in Healthy Volunteers (Aim 2B)

The overall purpose of this study is to determine how variation in the CYP4F2 gene modulates the synthesis of vitamin K-dependent clotting factors. We propose that the CYP4F23 gene variant increases short- and long-term vitamin K concentrations in the liver by reducing the efficiency of vitamin K metabolism. The investigators …

  • 25 Jan, 2021
  • 1 location