Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 459 clinical trials
Effect of Cladribine Treatment on Microglial Activation in the CNS (CLADPET)

To evaluate the effect of cladribine treatment on microglial activation with conventional MRI, QSM-post processing and TSPO-PET imaging in late stage relapsing remitting multiple sclerosis

cladribine
relapsing multiple sclerosis
MRI
  • 0 views
  • 25 Feb, 2022
  • 1 location
DiagnosE Using the Central veIn SIgn (DECISIve)

There is currently no agreement on the best way to diagnose Multiple Sclerosis (MS). Frequently, people suspected of having MS have a standard MRI scan and undergo a 'lumbar puncture' (a thin

clinically isolated syndrome
oligoclonal bands
MRI
disease or disorder
  • 1 views
  • 28 Feb, 2022
  • 3 locations
Assessing the Feasibility of the MSPT Device in Routine Clinical Practice in the Swiss Healthcare System

The Multiple Sclerosis Functional Composite (MSFC), a reliable and well-validated instrument, was developed as a multidimensional quantitative measure of neurologic disability in MS. However

clinically isolated syndrome
disease or disorder
  • 32 views
  • 25 Jan, 2021
  • 1 location
Mechanistic Study of Ocrevus

The purpose of this study is to investigate the immune cell and other factor changes with Ocrevus in Multiple Sclerosis (MS) patients. Researchers will recruit 35 participants for this study

immunosuppressive agents
cancer
disease or disorder
ocrelizumab
  • 0 views
  • 08 Aug, 2021
  • 1 location
Effect of Teriflunomide Treatment on Microglial Activation in an MS Patient Cohort at Risk of Progression

To evaluate the effect of teriflunomide treatment on microglial activation in late stage multiple sclerosis.

brain mri
teriflunomide
  • 0 views
  • 20 Oct, 2021
  • 1 location
A Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)

To evaluate the effectiveness, safety and Patient-Reported Outcomes (PROs) of cladribine tablets in participants with RMS including relapsing-remitting multiple sclerosis (RRMS) and active

cladribine
chronic progressive multiple sclerosis
relapsing multiple sclerosis
secondary progressive multiple sclerosis
disease or disorder
  • 306 views
  • 26 May, 2022
  • 41 locations
An Observational Study on Teriflunomide-exposed Pregnancies

Primary Objective: To evaluate any potential increase in the risk of major birth defects, in the first year of life, in teriflunomide-exposed pregnancies. Secondary Objective: To evaluate the potential effect of teriflunomide-exposure on other adverse pregnancy outcomes including any potential pattern of minor birth defects, spontaneous abortion, stillbirth, preterm delivery, …

teriflunomide
Accepts healthy volunteers
  • 8 views
  • 27 May, 2022
  • 2 locations
The Relationship of Neuropathic Pain With Incontinence, Disability and Life Quality in Multiple Sclerosis Patients

The aim of this study to evaluate the relationship of neuropathic pain with urinary and bowel incontinence, functional disability and quality of life in patients with multiple sclerosis.

  • 0 views
  • 27 May, 2022
  • 1 location
Long Term Special Drug Use-results Surveillance for Mayzent in SPMS Patients

This study is a single cohort, central registration system, all-case, open-label, multicenter observational study in patients using Mayzent for the indication of secondary progressive multiple

secondary progressive multiple sclerosis
  • 0 views
  • 05 May, 2022
  • 167 locations
Motor Skill Acquisition Between Individuals With Neurological Disorders and Healthy Individuals

Stroke survivors frequently show persistent gait deficits in their chronic stages even after years of intensive rehabilitation. This may be caused by diminished capability of re-acquiring motor skills post stroke. Thus, the overall purpose of this research project is to examine stroke survivors' capability of learning a novel leg task …

chronic stroke
range of motion exercise
nervous system disorder
neurological disorder
hemiparesis
  • 0 views
  • 25 Jan, 2021