Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 113 clinical trials
Testing the Addition of the Immunotherapy Drug Pembrolizumab to the Usual Chemotherapy Treatment (Paclitaxel and Carboplatin) in Stage III-IV or Recurrent Endometrial Cancer

This phase III trial studies how well the combination of pembrolizumab, paclitaxel and carboplatin works compared with paclitaxel and carboplatin alone in treating patients with endometrial cancer that is stage III or IV, or has come back (recurrent). Immunotherapy with monoclonal antibodies, such as pembrolizumab, may help the body's immune …

endometrioid adenocarcinoma
clear cell adenocarcinoma
step 2
papillary serous adenocarcinoma
undifferentiated carcinoma
  • 198 views
  • 09 Aug, 2022
  • 183 locations
The ARIES HeartMate 3 Pump IDE Study

Prospective, randomized, double-blinded, placebo-controlled clinical investigation of advanced heart failure patients treated with the HM3 with two different antithrombotic regimens: vitamin K antagonist with aspirin versus vitamin K antagonist with placebo

heart failure
aspirin
  • 8 views
  • 11 Aug, 2022
  • 48 locations
TRILUMINATE Pivotal Trial

The primary objective of this trial is to demonstrate the safety and effectiveness of the TriClip device in improving clinical outcomes in symptomatic patients with severe tricuspid regurgitation (TR), who are at intermediate or greater estimated risk for mortality or morbidity with tricuspid valve surgery. This randomized controlled trial will …

tricuspid valve repair
fibrillation
diuretics
repair of tricuspid valve
regurgitation
  • 156 views
  • 10 Aug, 2022
  • 80 locations
Genetic Testing in Screening Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been or Will Be Removed by Surgery (The ALCHEMIST Screening Trial)

This ALCHEMIST trial studies genetic testing in screening patients with stage IB-IIIA non-small cell lung cancer that has been or will be removed by surgery. Studying the genes in a patient's tumor cells may help doctors select the best treatment for patients that have certain genetic changes.

metastasis
cancer
pembrolizumab
paclitaxel
lung cancer
  • 1154 views
  • 08 Aug, 2022
  • 1029 locations
Calorie Restriction in Multiple Sclerosis (Calorie-MS)

"metabolic work load" represents a novel issue linking metabolism with loss of self-immune tolerance. Several disease-modifying drugs have been approved for Relapsing-remitting Multiple Sclerosis (RR-MS

  • 0 views
  • 10 Aug, 2022
  • 1 location
A Study of Lu AG06466 for the Treatment of Spasticity in Participants With Multiple Sclerosis

The main purpose of this study is to investigate Lu AG06466 as a treatment for spasticity in participants with multiple sclerosis (MS).

dalfampridine
baclofen
spasticity
  • 0 views
  • 08 Aug, 2022
  • 7 locations
PET Imaging of Cyclooxygenase-2 in Multiple Sclerosis

Background Multiple sclerosis (MS) is an autoimmune disease that has no cure. MRI is the main tool used in the study and treatment of people with MS. A tracer has

disease or disorder
MRI
  • 10 views
  • 11 Aug, 2022
  • 1 location
Immersive Virtual Reality for Upper Limb Rehabilitation in Multiple Sclerosis

. However, the use of VR within the multiple sclerosis (MS) population is not widely investigated, and even less with regards to upper limb function. The main aim of this study is to assess the feasibility

  • 0 views
  • 11 Aug, 2022
  • 1 location
A Study To Determine The Effect Of Ocrelizumab On Leptomeningeal Inflammation In Multiple Sclerosis (LEGATO)

progressive multiple sclerosis (MS). In addition, this study will investigate if the presence of leptomeningeal inflammation is associated with alterations of B cell repertoire and whether therapy with

secondary progressive multiple sclerosis
ocrelizumab
MRI
  • 0 views
  • 11 Aug, 2022
  • 2 locations
Lower Extremities Closed Kinetic Chain Exercises for People With MS

In total, 27 patients with MS (Expanded Disability Status Scale (EDSS) score equal to or less than 5.5) were randomly assigned to either Telko plus conventional physical therapy (CPT

  • 0 views
  • 08 Aug, 2022
  • 1 location