Multiple Sclerosis Clinical Trials

A listing of Multiple Sclerosis medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 47 clinical trials
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Long-term Safety Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

hemocyanin (KLH) neo-antigen in subjects with relapsing multiple sclerosis (RMS).

tetanus
pneumococcal conjugate vaccine
ofatumumab
  • 290 views
  • 01 Dec, 2021
  • 262 locations
None
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance and

  • 0 views
  • 23 Nov, 2021
  • 172 locations
None
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance and

  • 0 views
  • 23 Nov, 2021
  • 161 locations
None
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance and

contraceptive use
pregnancy test urine
hmr1726
brain lesion
teriflunomide
  • 10 views
  • 29 Nov, 2021
  • 284 locations
None
Relapsing Forms of Multiple Sclerosis (RMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168)

with relapsing forms of MS Secondary Objective: To assess efficacy of SAR442168 compared to teriflunomide (Aubagio) on disability progression, MRI lesions, cognitive performance and

contraceptive use
pregnancy test urine
hmr1726
brain lesion
teriflunomide
  • 0 views
  • 29 Nov, 2021
  • 293 locations
None
An Open-label Study Evaluating Ofatumumab Treatment Effectiveness and PROs in Subjects With RMS Transitioning From Dimethyl Fumarate or Fingolimod to Ofatumumab

The open label study to evaluate effectiveness of treatment with ofatumumab in patients transitioning from commonly used oral MS therapies - fingolimod or dimethyl fumarate, due to breakthrough

dimethyl fumarate
ofatumumab
fingolimod
  • 0 views
  • 01 Dec, 2021
  • 130 locations
None
Effects of Cladribine Tablets on the PK of Microgynon

The purpose of this study is to investigate the potential effects of cladribine on the pharmacokinetics (PK) of monophasic oral contraceptive microgynon by assessment of its constituents, ethinyl estradiol (EE) and levonorgestrel (LNG).

  • 5 views
  • 18 Nov, 2021
  • 15 locations
None
A Open-label Study to Assess Response to COVID-19 Vaccine in Multiple Sclerosis Participants Treated With Ofatumumab

This study will evaluate if participants treated with ofatumumab 20 mg subcutaneous (s.c.) administered once monthly can develop an adequate immune response to the COVID-19 mRNA vaccine compared to participants on an interferon or glatiramer acetate.

  • 0 views
  • 01 Dec, 2021
  • 2 locations
None
Surgical Weight Loss and Alcohol Perception

pilot data on the effects of metabolic surgery (MS), also known as bariatric surgery, on the metabolism of alcohol. These data will be used as preliminary evidence in support of a subsequent application

bypass surgery
roux-en-y
Accepts healthy volunteers
gastric bypass
  • 62 views
  • 18 Nov, 2021
  • 1 location
None
Efficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple Sclerosis

Efficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosis

fingolimod
  • 0 views
  • 01 Dec, 2021
  • 7 locations