Multiple Myeloma Clinical Trials

A listing of Multiple Myeloma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 104 clinical trials
Study of Daratumumab in Patients With Mild to Moderate Alzheimer's Disease (DARZAD)

This is an open-label, pilot study designed to explore whether daratumumab may have a clinically meaningful effect in patients with mild to moderate Alzheimer's disease.

mental state examination
amyloidosis
rivastigmine
mini-mental state examination
memantine
  • 132 views
  • 24 Jan, 2022
  • 1 location
Pixatimod (PG545) Plus Nivolumab in PD-1 Relapsed/Refractory Metastatic Melanoma and NSCLC and With Nivolumab and Low-dose Cyclophosphamide in MSS Metastatic Colorectal Carcinoma (mCRC)

The primary goal of this trial is to assess clinical response to nivolumab and pixatimod, and, nivolumab, pixatimod and cyclophosphamide in three separate patient cohorts. Cohort 1: MSS mCRC in combination with low-dose cyclophosphamide, Cohort 2: PD-1 relapsed/refractory melanoma, and Cohort 3: PD-1 relapsed/refractory NSCLC.

nivolumab
squamous cell carcinoma
lung carcinoma
progressive disease
targeted therapy
  • 0 views
  • 16 Jan, 2022
  • 1 location
Daratumumab Plus Ibrutinib in Patients With Waldenstr m's Macroglobulinemia

This study evaluates the safety and efficacy of daratumumab in combination with ibrutinib in patients with Waldenstrm's macroglobulinemia (WM). The study will evaluate this combination in two cohorts. Cohort A will comprise of ibrutinib nave WM patients. Patients in this cohort may be treatment nave or relapsed but who remain …

cytopenia
measurable disease
neutrophil count
human chorionic gonadotropin
ibrutinib
  • 1 views
  • 29 Dec, 2021
  • 1 location
PRECISE CURATE.AI Pilot Clinical Trial

In the current clinical context, drug dosing in oncology is dictated by toxicity. The optimal dosages of drugs in combinatory regimens for solid tumours are not clear, and the typical physician's decision on dose adjustment is a clinical judgement based on the degree of toxicity experienced by the patient. CURATE.AI …

neutrophil count
capecitabine
  • 0 views
  • 15 Jan, 2022
  • 3 locations
A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

participants with previously treated relapsed and/or refractory multiple myeloma.

  • 0 views
  • 09 Jan, 2022
  • 2 locations
A Non-interventional, Multinational, Observational Study With Isatuximab in Patients With Relapsed and/or Refractory Multiple Myeloma (RRMM) (IONA-MM)

item myeloma questionnaire module (QLQ MY20) Secondary Objective: Not applicable

carfilzomib
cancer
dexamethasone
refractory multiple myeloma
  • 0 views
  • 22 Jan, 2022
  • 55 locations
Collection of Samples and Clinical Data From Patients With Amyloid Diseases

RATIONALE: Collecting and storing samples of blood, urine, tissue and data from patients with amyloid diseases to test in the laboratory may help the study of this disease in the future. PURPOSE: This research study is collecting samples from patients with amyloid diseases

  • 21 views
  • 23 Jan, 2022
  • 1 location
Bergamo Lymphoid Cancer Registry

This registry has been established to gain a better understanding of the clinical and biological characteristics and outcome of patients with lymphoid cancer

cancer
multiple myeloma
hodgkin's disease
lymphoma
  • 4 views
  • 03 Jan, 2022
  • 1 location
Investigation of the Human Immune Response in Normal Subjects and Patients With Disorders of the Immune System and Cancer

This protocol is being submitted to consolidate, update, and expand two previously approved protocols (77-C-0066 and 82-C-0044) into a single protocol. The purpose of this study is to examine the factors involved in the regulation of the immune system of healthy individuals and to define the abnormalities in this regulation …

apheresis
blood transfusion
platelet count
cancer
autoimmune disorder
  • 16 views
  • 22 Jan, 2022
  • 1 location
Collection and Storage of Tissue and Blood Samples From Patients With Cancer

This research trial collects and stores tissue and blood samples from patients with cancer. Collecting and storing samples of tissue and blood from patients with cancer to study in the laboratory may help scientists create new and better models to learn about cancer and to test new cancer drugs.

multiple myeloma
cytology specimen collection procedure
metastasis
metastatic solid tumor
cancer diagnosis
  • 86 views
  • 17 Jan, 2022
  • 22 locations