Multiple Myeloma Clinical Trials

A listing of Multiple Myeloma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 112 clinical trials
ECT-001 (UM171) Expanded Cord Blood Transplant to Treat High-risk Multiple Myeloma

Multiple Myeloma (MM) is a morbid disease associated with a poor outcome and while current therapies with new drugs have improved survival, MM still remains incurable in most patients. The only

lenalidomide
graft versus host disease
leukemia
plasma cell leukemia
bortezomib
  • 65 views
  • 19 Jan, 2022
  • 3 locations
Multi-center, Open-label, Phase 1b Study in Patients With Relapsed/Refractory Multiple Myeloma (RRMM)

Primary Objectives: To evaluate the safety and tolerability of isatuximab administered subcutaneously (SC) versus intravenously (IV) To assess the safety and tolerability (including local injection site tolerability) of isatuximab using the (investigational) isatuximab injector device To evaluate the pharmacokinetics (PK) of SC and IV isatuximab Secondary Objectives: To estimate absolute …

refractory multiple myeloma
dexamethasone
lenalidomide
measurable disease
  • 0 views
  • 22 Jan, 2022
  • 8 locations
Carfilzomib Pomalidomide and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

multiple myeloma. This portion of the study is complete. This study will also investigate the effects of adding daratumumab to the combination of carfilzomib, pomalidomide and dexamethasone.

platelet count
immunoglobulins
pomalidomide
serum proteins
electrophoresis
  • 6 views
  • 16 Jan, 2022
  • 1 location
BCMA-directed CAR-T Cell Therapy in Adult Patients With Relapsed and/or Refractory Multiple Myeloma

)-specific chimeric antigen receptor (CAR) and manufactured with a new process. CAR-T cells will be investigated as a single agent in relapsed/refractory multiple myeloma

pomalidomide
immunomodulatory imide drug
bcma
measurable disease
carfilzomib
  • 0 views
  • 18 Jan, 2022
  • 2 locations
A Study of Denosumab in Multiple Myeloma Patients With Renal Insufficiency

This research study is studying a possible therapy as a possible treatment for the consequences of Multiple Myeloma with renal insufficiency.

monoclonal protein
bisphosphonate
plasmacytoma
bone marrow procedure
serum calcium
  • 0 views
  • 27 Jan, 2022
  • 7 locations
Kappa-CD28 T Lymphocytes, Chronic Lymphocytic Leukemia, B-cell Lymphoma or Multiple Myeloma, CHARKALL (CHARKALL)

Patients have a type of cancer called NHL, Multiple Myeloma (MM) or CLL that has come back or has not gone away after treatment. There is no standard treatment for the cancer at this time or the

chemotherapy regimen
monoclonal protein
immunoglobulins
chronic lymphocytic leukemia
measurable disease
  • 88 views
  • 23 Jan, 2022
  • 2 locations
Isatuximab in Treating Patients With High Risk Smoldering Plasma Cell Myeloma

This phase II trial studies how well isatuximab works in treating patients with high risk smoldering plasma cell myeloma. Immunotherapy with monoclonal antibodies, such as isatuximab, may induce

monoclonal protein
isatuximab
platelet count
monoclonal antibodies
bone marrow plasma cells
  • 122 views
  • 27 Jan, 2022
  • 3 locations
Testing the Addition of KRT-232 (AMG 232) to Usual Chemotherapy for Relapsed Multiple Myeloma

cell growth. Lenalidomide help shrink or slow the growth of multiple myeloma. Drugs used in chemotherapy, such as carfilzomib and dexamethasone, work in different ways to stop the growth of cancer

chemotherapy regimen
amg 232
monoclonal protein
platelet count
bone marrow procedure
  • 27 views
  • 18 Jan, 2022
  • 4 locations
Study of Plinabulin and Pegfilgrastim in People With Multiple Myeloma Undergoing an Autologous Hematopoietic Stem Cell Transplant (AHCT)

This study will see how long it takes for white blood cell counts to return to normal in people with multiple myeloma (MM) who receive plinabulin and pegfilgrastim after undergoing an autologous

melphalan
stem cell infusion
platelet count
human chorionic gonadotropin
  • 0 views
  • 31 Dec, 2021
  • 1 location
A Study of Health-Related Quality of Life in People With Multiple Myeloma Receiving Daratumumab or Lenalidomide

The purpose of this study is to compare maintenance therapy approaches in people with newly diagnosed multiple myeloma (MM) that has responded well to a first round of treatment. The researchers

line of therapy
cancer
heparin
antiviral
aspirin
  • 0 views
  • 19 Jan, 2022
  • 7 locations