Multiple Myeloma Clinical Trials

A listing of Multiple Myeloma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 35 clinical trials
Efficacy and Safety Study of bb2121 Versus Standard Regimens in Subjects With Relapsed and Refractory Multiple Myeloma (RRMM) (KarMMa-3)

This is a multicenter, randomized, open-label, Phase 3 study comparing the efficacy and safety of bb2121 versus standard regimens in subjects with relapsed and refractory multiple myeloma (RRMM

progressive disease
proteasome inhibitor
ixazomib
refractory multiple myeloma
bortezomib
  • 57 views
  • 11 Aug, 2022
  • 2 locations
A Safety and Efficacy Study of JNJ-68284528 (Ciltacabtagene Autoleucel) Out-of-Specification (OOS) for Commercial Release in Patients With Multiple Myeloma

The purpose of this study is to evaluate the efficacy and safety of cilta-cel out-of-specification (OOS).

chemotherapy regimen
fludarabine
human chorionic gonadotropin
  • 0 views
  • 19 Aug, 2022
  • 14 locations
A Diagnostic Study of CD38-Targeted ImmunoPET of Myeloma

Evaluation of myeloma disease burden is currently suboptimal. This limits treatment planning and evaluation of residual disease following treatment. 89Zr-DFO-daratumumab is a novel immunoPET

immunohistochemistry
  • 0 views
  • 11 Aug, 2022
  • 1 location
Belantamab Mafodotin, Pomalidomide and Dexamethasone for the Treatment of High-Risk Myeloma

This phase II trial studies the effect of belantamab mafodotin, pomalidomide, and dexamethasone in treating patents with high-risk myeloma. Belantamab mafodotin is a monoclonal antibody, called

chemotherapy regimen
dexamethasone
cancer
  • 0 views
  • 08 Aug, 2022
  • 1 location
Maintenance Belantamab Mafodotin (Blenrep®) After B-cell Maturation Antigen-Directed Chimeric Antigen Receptor T-cell Therapy in Patients With Relapsed and/or Refractory Multiple Myeloma (EMBRACE)

This is a multicenter phase II, open-label study evaluating the efficacy and safety of belantamab mafodotin maintenance in participants with relapsed and/or refractory multiple myeloma (RRMM

  • 0 views
  • 09 Aug, 2022
  • 1 location
Study of Palifermin (Kepivance) in Persons Undergoing Unrelated Donor Allogeneic Hematopoietic Cell Transplantation

Background In allogeneic stem cell transplantation (SCT), stem cells are taken from a donor and given to a recipient. Sometimes the recipient s immune system destroys the donor s cells. Or donor immune cells attack the recipient s tissues, called graft-versus-host disease (GVHD). This is less likely when the recipient …

progressive disease
white blood cells
bone lesion
blast crisis
bone marrow transplant
  • 23 views
  • 09 Aug, 2022
  • 2 locations
Study of STRO-001, an Anti-CD74 Antibody Drug Conjugate, in Patients With Advanced B-Cell Malignancies

First-in-human Phase 1 trial to study the safety, pharmacokinetics and preliminary efficacy of STRO-001 given intravenously every 3 weeks.

measurable disease
cancer
bone marrow procedure
  • 186 views
  • 10 Aug, 2022
  • 11 locations
Daratumumab and Pomalidomide in Previously Treated Patients With AL Amyloidosis (DarPAL)

This study aims at establishing a new powerful combination of daratumumab and pomalidomide as rescue treatment for patients with R/R AL amyloidosis.

dexamethasone
daratumumab
bone marrow procedure
alkylating agent
  • 0 views
  • 08 Aug, 2022
  • 2 locations
SG2501 Safety Study in Subjects With Relapsed or Refractory Hematological Malignancies and Lymphoma.

This is a phase Ia/Ib, first-in-Human, open-Label, multicenter, dose escalation and dose expansion study designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, immunogenicity, and preliminary efficacy of SG2501 in subjects with relapsed or refractory hematological malignancies and lymphoma.

progressive disease
white blood cells
platelet count
bone marrow transplant
multiple myeloma
  • 0 views
  • 09 Aug, 2022
  • 1 location
Autologous Stem Cell Transplant for Crohn's Disease

Crohn's Disease (CD) is an inflammatory bowel disease. It can lead to significant complications and discomfort in the stomach and intestines. Crohn's disease is a debilitating, incurable disease of immune cells; it affects almost 1 million people in the United States. CD is characterized by inflammation of the stomach and …

ct enterography
vedolizumab
golimumab
certolizumab pegol
methotrexate
  • 81 views
  • 09 Aug, 2022
  • 1 location