Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 715 clinical trials
Double Immune Checkpoint Inhibitors in PD-L1-positive Stage IV Non-small Lung CancEr

immunotherapy is not clear. Indeed, prolonged responses and long survivals have been described in patients having interrupted the treatment. In the melanoma, a treatment of 6 months of ipilimumab demonstrated

nivolumab
liver metastasis
ipilimumab
pd-l1
metastasis
  • 22 views
  • 25 Jan, 2021
  • 46 locations
Study of Quavonlimab (MK-1308) in Combination With Pembrolizumab (MK-3475) in Advanced Solid Tumors (MK-1308-001)

This study will assess the safety, tolerability, pharmacokinetics (PK), and preliminary efficacy of escalating doses of quavonlimab when used in combination with pembrolizumab in participants with advanced solid tumors.

  • 835 views
  • 19 Jan, 2022
  • 39 locations
Intermittent Selumetinib for Uveal Melanoma

The purpose of this study is to find out what effects, good and/or bad, intermittent dosing of the drug Selumetinib will have on subjects with uveal melanoma. Selumetinib is a drug that blocks

neutrophil count
spiral ct scan
platelet count
liver disease
mek inhibitor
  • 0 views
  • 27 Mar, 2021
  • 3 locations
ITIL-168 in Advanced Melanoma

DELTA-1 is a phase 2 clinical trial to evaluate the efficacy and safety of ITIL-168 in adult subjects with advanced melanoma who have previously been treated with a PD-1 inhibitor. ITIL-168 is a

  • 0 views
  • 18 Jan, 2022
  • 10 locations
A Study of Toripalimab or Combining With Temozolomide iv in the Treatment of Advanced/Metastatic Malignant Melanoma

This study evaluate toripalimab or combining with temozolomide for injection in the treatment of advanced/metastatic malignant melanoma. Participants in arm A receive toripalimab, in arm B

BRAF
systemic therapy
temozolomide
braf v600e mutation
  • 0 views
  • 24 May, 2021
  • 1 location
Cabozantinib and Pembrolizumab for Advanced Metastatic Melanoma

The study aims to evaluate the safety and preliminary efficacy of the combination of cabozantinib and pembrolizumab in advanced melanoma

  • 0 views
  • 25 Sep, 2021
  • 1 location
Dexamethasone Implant for Retinal Detachment in Uveal Melanoma

This is an investigator-initiated Phase I study of a single dose of an intravitreally-administered dexamethasone implant (Ozurdex) in subjects with uveal melanomas (UM) and exudative retinal

  • 0 views
  • 07 Aug, 2021
Dendritic Cells Plus Autologous Tumor RNA in Uveal Melanoma

Patients suffering from uveal melanoma (typed positive for monosomy 3 and without evidence for metastases) will be vaccinated over a period of 2 years with Dendritic Cell loaded with autologous

therapeutic autologous dendritic cells
metastasis
  • 20 views
  • 09 May, 2021
  • 12 locations
Nivolumab Plus Relatlimab in Patients With Metastatic Uveal Melanoma

The purpose of this research is to test if a combination treatment of nivolumab and relatlimab will result in tumor reduction in patients with metastatic uveal melanoma.

  • 0 views
  • 09 Jan, 2022
  • 2 locations
Adoptive Tumor-infiltrating Lymphocyte Transfer With Nivolumab for Melanoma

with metastatic melanoma that failed immunotherapy.Tumor-infiltrating lymphocytes will be expanded from resected melanoma samples from the patient and expanded TILs will be transferred to the patient

nivolumab
metastatic melanoma
neutrophil count
liver metastasis
hepatitis b antigen
  • 0 views
  • 14 Aug, 2021
  • 1 location