Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 149 clinical trials
Neoadjuvant Immunotherapy With Tavo + Electroporation in Combination With Nivo. in Melanoma Patients

operable locally-regionally advanced melanoma.

nivolumab
serum pregnancy test
metastatic melanoma
metastasis
ct scan
  • 20 views
  • 05 Jan, 2022
  • 1 location
LUMINOS-102: Lerapolturev (PVSRIPO) With or Without Immune Checkpoint Blockade in Patients With Advanced PD-1 Refractory Melanoma

A Phase 2 study to investigate the efficacy and safety of lerapolturev alone or in combination with a programmed death receptor-1 (anti-PD-1) inhibitor.

  • 0 views
  • 20 Jan, 2022
  • 55 locations
PV-10 in Combination With Pembrolizumab for Treatment of Metastatic Melanoma

This is an international multicenter, open-label, sequential phase study of intralesional (IL) PV-10 in combination with immune checkpoint inhibition. Metastatic melanoma patients (Stage IV or

pembrolizumab
neutrophil count
metastatic melanoma
platelet count
EGFR
  • 78 views
  • 22 Jan, 2022
  • 5 locations
Neoadjuvant PD-1 Blockade in Patients With Stage IIB/C Melanoma

The main purpose of this study is to determine the rate of positive sentinel lymph nodes (i.e. the closest draining lymph node(s) to the primary melanoma site) and to test whether treatment with

anticoagulants
immunologic adjuvant
direct bilirubin
immunomodulators
mucosal melanoma
  • 10 views
  • 16 Jan, 2022
  • 1 location
APX005M in Combination With Systemic Pembrolizumab in Patients With Metastatic Melanoma

You are being asked to take part in this study because you have metastatic (cancer that has spread) melanoma. The goal of Part 1 of this clinical research study is to find the highest

pembrolizumab
metastatic melanoma
platelet count
ocular melanoma
cancer
  • 0 views
  • 26 Jan, 2022
  • 1 location
BGB324 in Combination With Pembrolizumab or Dabrafenib/Trametinib in Metastatic Melanoma

The purpose of the study is to assess the safety and efficacy of BGB324 given together with standard treatment, pembrolizumab or dabrafenib and trametinib, compared to standard treatment alone,

metastatic melanoma
dabrafenib
trametinib
measurable disease
pembrolizumab
  • 0 views
  • 27 Jan, 2022
  • 7 locations
A Clinical Trial to Evaluate a Melanoma Helper Peptide Vaccine Plus Dabrafenib and Trametinib (Mel61)

This study evaluates whether it is safe to administer a helper peptide vaccine with dabrafenib and trametinib. This study will also evaluate the effects of the combination of the peptide vaccine and dabrafenib and trametinib on the immune system. We will monitor these effects by performing tests in the laboratory …

immunologic adjuvant
metastatic melanoma
metastasis
BRAF
dabrafenib
  • 12 views
  • 28 Jan, 2022
  • 1 location
Vaccine Enriched, Autologous, Activated T-Cells Directed to Tumor in Patients With Relapsed/Refractory Melanoma (MARVSmALo)

The researchers will investigate if modified T-cells from a patients own system can be utilized to find and destroy metastatic melanoma tumor and thus improve patient outcomes.

oximetry
neutrophil count
metastatic melanoma
unresectable melanoma
  • 15 views
  • 29 Jan, 2022
  • 1 location
Nivolumab With Trametinib and Dabrafenib, or Encorafenib and Binimetinib in Treating Patients With BRAF Mutated Metastatic or Unresectable Stage III-IV Melanoma

melanoma that has spread to other places in the body (metastatic) or cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as nivolumab, may induce changes in the

nivolumab
immunologic adjuvant
metastatic melanoma
metastasis
BRAF
  • 130 views
  • 27 Jan, 2022
  • 1 location
Phase 2 Trial to Evaluate Safety and Efficacy of AU-011 Via Suprachoroidal Administration in Subjects With Primary Indeterminate Lesions and Small Choroidal Melanoma

The primary objective is to assess safety and efficacy of AU-011 via suprachoroidal injection to treat primary indeterminate lesions and small choroidal melanoma.

metastasis
choroid melanoma
  • 0 views
  • 02 Jan, 2022
  • 22 locations