Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 119 clinical trials
Duration of Anti-PD-1 Therapy in Metastatic Melanoma

The purpose of this study is to compare the effects on patients with metastatic melanoma of taking a government approved and paid-for PD-1 inhibitor intermittently, with taking the same type of

  • 356 views
  • 18 Jan, 2022
  • 30 locations
A Phase II/III Trial of Nivolumab, Ipilimumab, and GM-CSF in Patients With Advanced Melanoma

melanoma that cannot be removed by surgery (unresectable). Immunotherapy with monoclonal antibodies, such as ipilimumab and nivolumab, may help the body's immune system attack the cancer, and may interfere

mdx-ctla-4
metastasis
immunomodulators
colony-stimulating factors
cancer
  • 114 views
  • 19 Jan, 2022
  • 464 locations
Efficacy, Safety, and Tolerability of V937 Administered Intravenously or Intratumorally With Pembrolizumab (MK-3475) Versus Pembrolizumab Alone in Participants With Advanced/Metastatic Melanoma (V937-011)

) versus pembrolizumab alone in anti-programmed cell death ligand 1 (anti-PD-L1)-treatment-naive participants with advanced/metastatic melanoma. The primary hypothesis of the study is that V937

  • 27 views
  • 30 Dec, 2021
  • 27 locations
A Study to Evaluate the Safety and Activity of Belvarafenib as a Single Agent and in Combination With Either Cobimetinib or Cobimetinib Plus Atezolizumab in Patients With NRAS-mutant Advanced Melanoma.

NRAS-mutant advanced melanoma who have received anti-PD-1/PD-L1 therapy.

melanoma skin
immunomodulators
malignant melanoma of skin
immunologic adjuvant
cobimetinib
  • 1 views
  • 16 Jan, 2022
  • 9 locations
A Study of SGN-CD228A in Advanced Solid Tumors

This trial will study SGN-CD228A to find out whether it is an effective treatment for different kinds of cancer. It will also look at what side effects (unwanted effects) may occur. The study will have two parts. Part 1 of the study will find out how much SGN-CD228A should be …

progressive disease
metastasis
malignant melanoma of skin
biomarker analysis
lung carcinoma
  • 15 views
  • 19 Jan, 2022
  • 17 locations
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)

This is a two-part study of pembrolizumab (MK-3475) in pediatric participants who have any of the following types of cancer: advanced melanoma (6 months to <18 years of age

hodgkin's disease
solid tumour
pembrolizumab
malignant solid tumor
pd-l1
  • 93 views
  • 24 Jan, 2022
  • 18 locations
Study of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid Tumors

A prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL LN-144 (Lifileucel)/LN-145 in combination with checkpoint inhibitors or TIL LN-144 (Lifileucel)/LN-145/LN-145-S1 as a single agent therapy.

systemic therapy
metastatic squamous cell carcinoma
solid tumour
nivolumab
stage iv non-small cell lung cancer
  • 123 views
  • 26 Dec, 2021
  • 50 locations
A Phase 2 Study of NIR178 in Combination With PDR001 in Patients With Solid Tumors and Non-Hodgkin Lymphoma

The purpose of this phase 2 study is to evaluate the efficacy and safety of NIR178 in combination with PDR001 in multiple solid tumors and diffuse large B-cell lymphoma (DLBCL) and further explore schedule variations of NIR178 to optimize immune activation through inhibition of A2aR.

BRAF
melanoma skin
malignant melanoma of skin
irinotecan
triple negative breast cancer
  • 235 views
  • 16 Jan, 2022
  • 20 locations
A Study of SAR444245 Combined With Cemiplimab for the Treatment of Participants With Various Advanced Skin Cancers

Primary Objective: -To determine the antitumor activity of SAR444245 in combination with cemiplimab. Secondary Objectives: To determine the recommended phase 2 dose and to assess the safety profile of SAR444245 when combined with cemiplimab To assess other indicators of antitumor activity To assess the concentrations of SAR444245 when given in …

metastasis
measurable disease
metastatic melanoma
  • 0 views
  • 23 Jan, 2022
  • 12 locations
A Study of Ladiratuzumab Vedotin in Advanced Solid Tumors

This trial will study ladiratuzumab vedotin (LV) to find out if it works to treat different types of solid tumors. It will also find out what side effects may occur. A side effect is anything the drug does besides treating cancer.

progressive disease
BRAF
metastasis
growth factor
melanoma skin
  • 12 views
  • 16 Jan, 2022
  • 71 locations