Melanoma Clinical Trials

A listing of Melanoma medical research trials actively recruiting patient volunteers. Search for closest city to find more detailed information on a research study in your area.

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Found 320 clinical trials
T Cell Receptor Gene Therapy Targeting KK-LC-1 for Gastric, Breast, Cervical, Lung and Other KK-LC-1 Positive Epithelial Cancers

Background Researchers have found a new way to treat cancer using T cell therapy. The therapy used in this study is T Cell Receptor (TCR) Gene Therapy Targeting KK-LC-1, a cancer germline antigen that is expressed by certain cancers. This therapy is a type of treatment in which a participant …

  • 0 views
  • 27 Jun, 2022
  • 1 location
NeoAdjuvant Therapy With Immunoreagent (SHR-1316) for Resectable Oesophageal Squamous Cell carciNoma (NATION1907II)

The investigators will conduct a prospective, single-arm study to evaluate the safety and feasibility of neoadjuvant therapy with anti-PD-L1 antibody (SHR-1316, Hengrui Medicine) in patients with resectable esophageal squamous cell carcinoma (ESCC).

  • 0 views
  • 28 Jun, 2022
  • 1 location
NeoVax Plus Ipilimumab in Renal Cell Carcinoma

This research study is evaluating a new type of Kidney Cancer vaccine called "Personalized NeoAntigen Cancer Vaccine"as a possible treatment for Kidney Cancer. The following intervention will be involved in this study: Personalized Neoantigen Vaccine Poly-ICLC (Hiltonol) Ipilimumab

clear cell renal cell carcinoma
cancer
neutrophil count
ipilimumab
carcinoma
  • 0 views
  • 08 Apr, 2022
Ipilimumab With or Without Nivolumab in Relapsed/Refractory cHL

This study is looking at the effects of Ipilimumab when it is given alone or in combination with Nivolumab to patients with relapsed or refractory classic Hodgkin's lymphoma (cHL). The names of the study drugs involved in this study are: Ipilimumab Nivolumab

lymphoma
nivolumab
cell transplantation
measurable disease
  • 0 views
  • 30 Apr, 2022
  • 3 locations
Ultrasound in Diagnosing Patients With Skin Lesions

This trial studies the use of a novel non-invasive ultrasound technique in diagnosing patents with skin lesions. Diagnostic procedures, such as ultrasound, may be a less invasive way to check skin lesions for skin cancer and other skin disorders.

  • 0 views
  • 05 Jun, 2022
  • 1 location
A Single Dose of Pembrolizumab in HIV-Infected People

Background Human immunodeficiency virus (HIV) attacks the immune system. Some people with HIV have a low CD4+ T-cell count despite taking antiviral medicines that control HIV replication. These cells fight disease, so a low count makes it easier for people to become sick. Researchers want to see if a new …

progestin
leukapheresis
HIV Vaccine
drug test
white blood cell count
  • 215 views
  • 15 Jun, 2022
  • 1 location
Low Dose IL-2 for the Treatment of Crohn's Disease

The purpose of this study is to determine the safety and maximum effective dose (MED) of Interleukin-2 in subjects with moderate-to-severe crohn's disease.

mercaptopurine
corticosteroids
ileal disease
remission
ustekinumab
  • 0 views
  • 06 Jun, 2022
  • 3 locations
Safety and Efficacy of Repeat Administration of Ad/PNP and Fludarabine Phosphate in Patients With Local Head/Neck Cancer

Primary Objective: The primary objective of the study is to evaluate the safety of repeat administration of a dose level of Ad/PNP plus fludarabine phosphate (F-araAMP) which demonstrated anti-tumor activity in patients with advanced, locoregional head/neck cancer in a completed phase I study. Secondary Objective: The secondary objective is to …

  • 8 views
  • 27 Apr, 2022
  • 1 location
A Trial of Ipatasertib in Combination With Atezolizumab (IceCAP)

This is a single centre, proof-of-concept phase I trial of atezolizumab in combination with ipatasertib. There are two parts to this study, the dose escalation phase (Part A) and the dose expansion phase (Part B). Part A, will determine the maximum tolerated dose (MTD) and recommended Phase II dose (RP2D). …

serum bilirubin
AKT
cancer
neutrophil count
PTEN
  • 125 views
  • 22 Apr, 2022
  • 1 location
Protein Phosphatase 2A Inhibitor, in Recurrent Glioblastoma

Background The brain is separated from the rest of the blood stream by the blood-brain barrier. This is like a filter that protects the brain. But is also a challenge when medicines need to get into the brain. Researchers want to give the new drug LB100 to people before brain …

recurrent glioblastoma
renal function
astrocytoma
glioblastoma multiforme
brain tumor
  • 22 views
  • 17 Jun, 2022
  • 1 location